A suggested positive control is HepG2 cell lysate.
PA5-20653 can be used with blocking peptide PEP-0773.
ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
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Protein Aliases: brain specific protein 2; Zinc finger and BTB domain-containing protein 1
Gene Aliases: 9430077A12; AI256369; Bsg2; C430003J21Rik; KIAA0997; ZBTB1; ZNF909