Immunogen sequence: LRSDIFEEVL NYMYTAKISV KKEDVNLMMS SGQILGIRFL DKLCSQKRDV SSPDENNGQS KSKYCLKINR PIGDAADTQD DDVEEIGDQD DSP
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene. Transcriptional repressor of MYC and thymidine kinase promoters.
Protein Aliases: ZF5; Zfp-161; ZFP161 zinc finger protein; Zinc finger and BTB domain-containing protein 14; Zinc finger protein 161 homolog; Zinc finger protein 478; Zinc finger protein 5 homolog; zinc finger protein homologous to Zfp161 in mouse
Gene Aliases: ZBTB14; ZF5; ZFP-161; ZFP-5; ZFP161; ZNF478
UniProt ID: (Human) O43829
Entrez Gene ID: (Human) 7541
Molecular Function: C2H2 zinc finger transcription factor