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Agrisera
ZCP1/Zinc Chaperone Protein Polyclonal Antibody
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FIGURE: 1 / 1
ZCP1/Zinc Chaperone Protein Antibody (AS14-2770) in WB
Chlamydomonas reinhardtii whole-cell extracts corresponding to 10 µL 1 x 10 7 cells/mL per well (except dilutions as indicated) were separated on a 12% SDS-PAGE gel and blotted to nitrocellulose for 90 min. at 1.5 m A cm-2. The membrane was blocked with 1% bovine calf serum in PBS-T overnight at 4 deg C. Blot was incubated in the primary antibody at a dilution of 1:1,000 for 2 hr at RT with agitation. The a... View More
Product Details
AS14-2770
Product Specifications
Species Reactivity
Algae
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant, full length ZCP1 protein of Chlamydomonas reinhardtii.
Conjugate
Form
Lyophilized
Storage buffer
whole serum
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Chlamydomonas reinhardtii
Target Information
ZCP1 (zona pellucida glycoprotein 1; ZP1) encodes a secreted, extracellular matrix glycoprotein that is synthesized by growing oocytes and incorporated into the zona pellucida surrounding the oocyte and early embryo. The gene produces multiple transcripts and a protein characterized by an N-terminal signal peptide for secretion and a conserved zona pellucida (ZP) domain (approximately 270 amino acids with conserved cysteines forming intramolecular disulfide bonds) that supports polymerization/assembly with other ZP proteins; in the assembled matrix, ZP1 functions primarily as a structural cross-linker that stabilizes and reinforces the fibrillar scaffold built largely from ZP2-ZP3, thereby maintaining zona pellucida integrity required for normal fertilization and preimplantation development. Experimental and clinical genetics evidence links loss-of-function or damaging variants in ZP1 to defective or absent zona pellucida, oocyte maturation defects, and female infertility, consistent with its essential role in constructing a functional oocyte coat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COG0523; ZNG1
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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