PA5-29094 targets FOG2/ZFPM2 in WB applications and shows reactivity with Human, Rat and mouse samples.
The PA5-29094 immunogen is recombinant fragment corresponding to a region within amino acids 280 and 564 of Human FOG2/ZFPM2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DIH3; FOG-2; FOG2; Friend of GATA 2; Friend of GATA protein 2; friend of GATA-1 2; friend of GATA-2; Friend of GATA2; hFOG-2; mFOG-2; modulator of; transcription factor GATA4; transcription factor GATA4, modulator of; Zinc finger protein 89B; Zinc finger protein multitype 2; Zinc finger protein ZFPM2; zinc finger protein, multitype 2; ZNF89B
Gene Aliases: B330005D23Rik; DIH3; FOG-2; FOG2; hFOG-2; SRXY9; ZC2HC11B; ZFPM2; ZNF89B