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Product Details
12680-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 3 publications 3 publications |
Immunocytochemistry (ICC/IF) |
Assay-dependent | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ZFYVE27 Fusion Protein Ag3369 (217-411 aa encoded by BC030621) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.31 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: VEFFRVVSE YRASLQQRMN PKQEEHAFES PPPPDVGGKD GLMDSTPALT PTEDLTPGSV EEAEEAEPDE EFKDAIEETH LVVLEDDEGA PCPAEDELAL QDNGFLSKNE VLRSKVSRLT ERLRKRYPTN NFGNCTGCSA TFSVLKKRRS CSNCGNSFCS RCCSFKVPKS SMGATAPEAQ RETVFVCASC NQTLSK (217-411 aa encoded by BC030621)
Target Information
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protrudin; RP11-459F3.2; Spastic paraplegia 33 protein; zinc finger FYVE domain containing 27; Zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27
Gene Aliases: 2210011N02Rik; 9530077C24Rik; AI426636; AI593546; AI835681; PROTRUDIN; SPG33; ZFYVE27
UniProt ID: (Human) Q5T4F4, (Rat) Q6P7B7, (Mouse) Q3TXX3
Entrez Gene ID: (Human) 118813, (Rat) 309376, (Mouse) 319740
Molecular Function:
membrane traffic protein
membrane trafficking regulatory protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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