This target displays homology in the following species: Cow: 93%; Dog: 93%; Horse: 93%; Human: 93%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants encoding the same protein.
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Protein Aliases: Zinc fingers and homeoboxes protein 1
Gene Aliases: Zhx1
UniProt ID: (Mouse) P70121
Entrez Gene ID: (Mouse) 22770