The MW of this protein is 51 kDa, and this antibody specifically recognizes the 51 kDa protein.
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
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Protein Aliases: Zinc finger protein 259; Zinc finger protein ZPR1
Gene Aliases: ZNF259; ZPR1
UniProt ID: (Human) O75312
Entrez Gene ID: (Human) 8882