Recommended positive controls: NT2D1, IMR32.
Predicted reactivity: Chicken (83%), Rhesus Monkey (99%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DBIRD complex subunit ZNF326; dJ871E2.1 (novel protein (ortholog of mouse zinc finger protein Zan75)); Zinc finger protein 326; Zinc finger protein interacting with mRNPs and DBC1; ZNF-protein interacting with nuclear mRNPs and DBC1
Gene Aliases: dJ871E2.1; ZAN75; Zfp326; ZIRD; ZNF326
UniProt ID: (Human) Q5BKZ1
Entrez Gene ID: (Human) 284695
Molecular Function: scaffold/adaptor protein