A suggested positive control is human brain tissue lysate.
PA5-20769 can be used with blocking peptide PEP-0883.
Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.
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Protein Aliases: Myocardial ischemic preconditioning up-regulated protein 1; myocardial ischemic preconditioning upregulated 1; myocardial ischemic preconditioning upregulated 1 ortholog; Zinc finger protein 667
Gene Aliases: A830025F02Rik; Mip1; MIPU1; Zfp667; ZNF667