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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 556 and 939 of Human ZO-1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
PA5-28869 targets ZO-1 in IF and WB applications and shows reactivity with Human samples.
The PA5-28869 immunogen is recombinant fragment corresponding to a region within amino acids 556 and 939 of Human ZO-1.
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice.
PA5-28869 was used in immunocytochemistry to determine if administration of resveratrol is beneficial for treating cystic fibrosis
|Dhooghe B,Bouckaert C,Capron A,Wallemacq P,Leal T,Noel S||Biology open (4:929)||2015|
tight junction protein ZO-1; ZO-1; zona occludens 1; zona occludens protein 1; zonula occludens 1 protein; zonula occludens protein 1
TJP1; ZO-1; ZO1