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Invitrogen
ZP4 Polyclonal Antibody
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FIGURE: 1 / 6
ZP4 Antibody (PA5-101974) in IHC (P)
Immunohistochemistry analysis of ZP4 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ZP4 polyclonal antibody (Product # PA5-101974) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-101974
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ZP4(Accession Q12836), corresponding to amino acid residues A231-L281.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ZP4.
Target Information
The mammalian zona pellucida is composed of four major glycoproteins, ZP1, ZP2, ZP3 and ZP4, which may act as sperm receptors. Two forms of porcine ZP4 peptides exist: one consisting of 128 amino acid residues and the other of 133 amino acid residues. These two peptides are identical, except the larger form contains an additional five amino acid sequence at its carboxy-terminal end. Both peptides have two potential N-linked glycosylation sites. The smaller peptide shares 39.1% identity with the amino-terminal region of mouse ZP2 polypeptide. Based on results from animal studies, ZP4 antigen is a promising candidate for the development of a contraceptive vaccine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: unnamed protein product; zona pellucida 4; zona pellucida B glycoprotein; zona pellucida protein B
Gene Aliases: ZBP; Zp-4; ZP1; ZP1B; ZPB; ZPB2
UniProt ID: (Human) Q12836
Entrez Gene ID: (Human) 57829, (Rat) 282833
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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