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Proteintech
ZRANB1 Polyclonal Antibody
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Product Details
27050-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZRANB1 fusion protein Ag25789
Conjugate
Form
Liquid
Concentration
600 µg/mL
Amount
90 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: MSERGIKWAC EYCTYENWPS AIKCTMCRAQ RPSGTIITED PFKSGSSDVG RDWDPSSTEG GSSPLICPDS SARPRVKSSY SMENANKWSC HMCTYLNWPR
Target Information
ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp762P2216; hTrabid; TRAF-binding domain-containing protein; TRAF-binding protein; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; unnamed protein product; Zinc finger Ran-binding domain-containing protein 1; zinc finger, RAN-binding domain containing 1
Gene Aliases: 9330160G10Rik; D7Wsu87e; Gm1956; TRABID; ZRANB1
UniProt ID: (Human) Q9UGI0, (Mouse) Q7M760
Entrez Gene ID: (Human) 54764, (Mouse) 360216
autophagosome assembly
proteolysis
cytoskeleton organization
Wnt signaling pathway
cell migration
protein deubiquitination
regulation of cell morphogenesis
positive regulation of Wnt signaling pathway
protein K29-linked deubiquitination
phosphatidylinositol phosphorylation
protein K63-linked deubiquitination
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
protein K33-linked deubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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