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Proteintech
ZWINT Polyclonal Antibody
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Product Details
12282-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ZWINT Fusion Protein Ag2933 (1-277 aa encoded by BC020979)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEAAETEAE AAALEVLAEV AGILEPVGLQ EEAELPAKIL VEFVVDSQKK DKLLCSQLQV ADFLQNILAQ EDTAKGLDPL ASEDTSRQKA IAAKEQWKEL KATYREHVEA IKIGLTKALT QMEEAQRKRT QLREAFEQLQ AKKQMAMEKR RAVQNQWQLQ QEKHLQHLAE VSAEVRERKT GTQQELDGVF QKLGNLKQQA EQERDKLQRY QTFLQLLYTL QGKLLFPEAE AEAENLPDDK PQQPTRPQEQ STGDTMGRDP GVSFKAVGLQ PAGDVNLP (1-277 aa encoded by BC020979)
Target Information
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: human ZW10 interacting protein-1; Outer kinetochore KNL1 complex subunit ZWINT; SNAP25 interacting protein of 30 kDa; unnamed protein product; ZW10 interactor; ZW10 interactor, kinetochore protein; ZW10-interacting protein 1; Zwint-1
Gene Aliases: HZwint-1; KNTC2AP; SIP30; ZWINT; ZWINT1
UniProt ID: (Human) O95229
Entrez Gene ID: (Human) 11130
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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