This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: GGLDSLMGDEP EGIGGTNFVA PPTAAVPANL GAPIGSGL
Highest antigen sequence identity to the following orthologs - mouse 67%, rat 74%.
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adapter-related protein complex 1 subunit beta-1; Adapter-related protein complex 2 subunit beta; Adaptor protein complex AP-1 subunit beta-1; adaptor protein complex AP-1, beta 1 subunit; adaptor-related protein complex 1 beta 1 subunit; Adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; adaptor-related protein complex AP-1 beta 1 subunit; adaptor-related protein complex AP-1, beta 1 subunit; ADTB1; ADTB2; AP-1 complex subunit beta-1; AP105A; AP1B1; AP2B1; BAM22; Beta-1-adaptin; Beta-adaptin 1; beta-prime adaptin; beta-prime-adaptin; beta1-adaptin; CLAPB1; CLAPB2; Clathrin assembly protein complex 1 beta large chain; Golgi adaptor HA1/AP1 adaptin beta subunit; Mutant line 1660; plasma membrane adaptor HA2/AP2 adaptor beta subunit
Gene Aliases: ADTB1; AP105A; AP1B1; b2b1660Clo; BAM22; CLAPB2
Molecular Function: membrane traffic protein