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Invitrogen
beta-2 Microglobulin/FCRN Polyclonal Antibody
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FIGURE: 1 / 2
beta-2 Microglobulin/FCRN Antibody (PA5-80367) in IHC (P)
Immunohistochemical staining of human FcRn ( beta-2 Microglobulin/FCRN Heterodimer) in human esophageal carcinoma with beta-2 Microglobulin/FCRN Polyclonal Antibody (Product # PA5-80367, 1:1,000, formalin-fixed paraffin embedded sections).
Product Details
PA5-80367
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human FCGRT & B2M Heterodimer Protein (1-297, 1-119).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human FCGRT & B2M Heterodimer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B2M; beta 2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; Beta-2-microglobulin; Fc fragment of IgG receptor and transporter; Fc fragment of IgG, receptor, transporter, alpha; FcRn; FcRn alpha chain; HDCMA22P; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig; neonatal fragment crystallizable Fc receptor FcRn; similar to Homo sapiens mRNA for beta 2-microglobulin with GenBank Accession Number AB021288; transmembrane alpha chain of the neonatal receptor; unnamed protein product
Gene Aliases: alpha-chain; AMYLD6; B2M; CDABP0092; FcgammaRn; FCGRT; FCRN; HDCMA22P; IMD43; MHC1D4
UniProt ID: (Human) P61769, (Human) P55899
Entrez Gene ID: (Human) 567, (Human) 2217
IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
immune response
T cell mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity
response to molecule of bacterial origin
immune system process
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
peptide antigen assembly with MHC class I protein complex
peptide antigen assembly with MHC class II protein complex
positive regulation of T cell cytokine production
regulation of membrane depolarization
iron ion transport
cellular iron ion homeostasis
sensory perception of smell
learning or memory
response to metal ion
negative regulation of neuron projection development
antibacterial humoral response
antigen processing and presentation of endogenous peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell differentiation in thymus
transferrin transport
regulation of iron ion transport
negative regulation of iron ion transport
protein refolding
innate immune response
regulation of erythrocyte differentiation
positive regulation of receptor-mediated endocytosis
negative regulation of receptor-mediated endocytosis
negative regulation of epithelial cell proliferation
negative regulation of neurogenesis
positive regulation of immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive regulation of T cell activation
protein homotetramerization
multicellular organismal iron ion homeostasis
antimicrobial humoral immune response mediated by antimicrobial peptide
cellular response to lipopolysaccharide
cellular response to iron ion
cellular response to iron(III) ion
cellular response to nicotine
amyloid fibril formation
positive regulation of cellular senescence
negative regulation of forebrain neuron differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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