Product References
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Antioxidants & redox signaling
Liu YT,Zhang H,Duan SB,Wang JW,Chen H,Zhan M,Zhang W,Li AM,Liu Y,Yang Y,Yang S
Mon Jan 01 00:00:00 EST 2024
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Neoplasma
Li GH,Liu X,Feng LJ,Zhang L
Sun Aug 20 00:00:00 EDT 2023
Huc-MSCs-derived exosomes attenuate neuropathic pain by inhibiting activation of the TLR2/MyD88/NF-κB signaling pathway in the spinal microglia by targeting Rsad2.
International immunopharmacology
Gao X,Gao LF,Zhang YN,Kong XQ,Jia S,Meng CY
Sun Jan 01 00:00:00 EST 2023
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
European journal of pharmacology
Wei P,Lin D,Zhang M,Luo C,Wu X,Deng B,Cui K,Chen Z
Thu Jan 05 00:00:00 EST 2023
Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo.
International immunopharmacology
Cai T,Ye H,Jiang H,Lin C,Lou C,Wang W,Yan Z,Xue X,Pan X,Lin J
Wed Feb 01 00:00:00 EST 2023
Proximal tubular Bmal1 protects against chronic kidney injury and renal fibrosis by maintaining of cellular metabolic homeostasis.
Biochimica et biophysica acta. Molecular basis of disease
Liu C,Li S,Ji S,Zhang J,Zheng F,Guan Y,Yang G,Chen L
Sun Jan 01 00:00:00 EST 2023
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
Biochemical pharmacology
Chen Z,Sun X,Li X,Liu N
Wed Feb 01 00:00:00 EST 2023
Ferroptosis is involved in PM2.5-induced acute nasal epithelial injury via AMPK-mediated autophagy.
International immunopharmacology
Gu W,Hou T,Zhou H,Zhu L,Zhu W,Wang Y
Wed Feb 01 00:00:00 EST 2023
Mutation-Driven S100A8 Overexpression Confers Aberrant Phenotypes in Type 1 CALR-Mutated MPN.
International journal of molecular sciences
Wang YH,Chen YJ,Lai YH,Wang MC,Chen YY,Wu YY,Yang YR,Tsou HY,Li CP,Hsu CC,Huang CE,Chen CC
Sun May 14 00:00:00 EDT 2023
Zika virus replication on endothelial cells and invasion into the central nervous system by inhibiting interferon β translation.
Virology
Wang K,Zou S,Chen H,Higazy D,Gao X,Zhang Y,Cao S,Cui M
Mon May 01 00:00:00 EDT 2023
RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation.
Cell death discovery
Zhu K,Gao T,Wang Z,Zhang L,Tan K,Lv Z
Mon May 08 00:00:00 EDT 2023
The PRMT5 inhibitor C9 mitigates hypoxia-induced carboplatin resistance in lung cancer by inducing autophagy.
Cell biology international
Fan J,Li H,Ruan Q,Zhu X,Jing P,Gu Z
Sun Oct 01 00:00:00 EDT 2023
Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
ACS chemical biology
Hill SE,Beaulieu-Abdelahad D,Lemus A,Webster JM,Ospina SR,Darling AL,Martin MD,Patel S,Bridenstine L,Swonger R,Paul S,Blackburn R,Calcul L,Dickey CA,Leahy JW,Blair LJ
Fri May 19 00:00:00 EDT 2023
Progressive degeneration of the retina in Loxl3 mutant mouse model of Stickler syndrome.
Developmental biology
Liu Z,Mo F,Dong X,Chen G,Gao J,Zhang J
Wed Mar 01 00:00:00 EST 2023
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
International journal of molecular sciences
Chen H,Tu M,Liu S,Wen Y,Chen L
Wed Jan 25 00:00:00 EST 2023
Garlic-derived exosomes regulate PFKFB3 expression to relieve liver dysfunction in high-fat diet-fed mice via macrophage-hepatocyte crosstalk.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Li W,Bian Y,Jiang X,Zhu F,Yin F,Yin L,Song X,Guo H,Liu J
Sat Apr 01 00:00:00 EDT 2023
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Materials today. Bio
Xu X,Zhang H,Li Y,Liu F,Jing Z,Ren M,Chen T,Fu Y,Wu Y,Ji P,Yang S
Thu Jun 01 00:00:00 EDT 2023
Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.
Journal of dairy science
Chen H,Qi X,Guan K,Wang R,Li Q,Ma Y
Sat Apr 01 00:00:00 EDT 2023
ARHGAP44 expression is associated with the metastasis of osteosarcoma and is a promising prognostic biomarker.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Hu S,Wang W
Thu Jun 01 00:00:00 EDT 2023
Tumor-derived endomucin promotes colorectal cancer proliferation and metastasis.
Cancer medicine
Huang Q,Li XM,Sun JP,Zhou Y
Wed Feb 01 00:00:00 EST 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Journal of ethnopharmacology
Zhu Y,Han Y,Wang W,Liang G,Qi J
Sat Jul 15 00:00:00 EDT 2023
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
International immunopharmacology
Peng X,Li Y,Zhao W,Yang S,Huang J,Chen Y,Wang Y,Gong Z,Chen X,Yu C,Cai S,Zhao H
Sat Apr 01 00:00:00 EDT 2023
Ubiquitin ligase MARCH8 promotes the malignant progression of hepatocellular carcinoma through PTEN ubiquitination and degradation.
Molecular carcinogenesis
Xu Y,Zhang D,Ji J,Zhang L
Sat Jul 01 00:00:00 EDT 2023
Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury.
Frontiers in physiology
Dai Q,Zhang H,Tang S,Wu X,Wang J,Yi B,Liu J,Li Z,Liao Q,Li A,Liu Y,Zhang W
Tue Mar 14 00:00:00 EDT 2023
The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis.
The Journal of biological chemistry
Hironaka T,Takizawa N,Yamauchi Y,Horii Y,Nakaya M
Wed Mar 01 00:00:00 EST 2023
Impact of age on the rotenone-induced sporadic Parkinson's disease model using Drosophila melanogaster.
Neuroscience letters
Li W,Pan X,Li M,Ling L,Zhang M,Liu Z,Zhang K,Guo J,Wang H
Sun May 14 00:00:00 EDT 2023
Toosendanin-induced apoptosis of CMT-U27 is mediated through the mitochondrial apoptotic pathway.
Veterinary and comparative oncology
Yang Y,Mei C,Xian H,Zhang X,Li J,Liang ZX,Zhi Y,Ma Y,Wang HJ
Thu Jun 01 00:00:00 EDT 2023
Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma.
Phytotherapy research : PTR
Zhu XF,Sun ZL,Ma J,Hu B,Yu MC,Liu XJ,Yang P,Xu Y,Ju D,Mu Q
Wed Feb 01 00:00:00 EST 2023
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
Biochemical and biophysical research communications
Zeng S,Tao M,Yuan L,Zhang L,Luo X
Sun Apr 23 00:00:00 EDT 2023
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Translational research : the journal of laboratory and clinical medicine
Lu Y,Tang K,Wang S,Tian Z,Fan Y,Li B,Wang M,Zhao J,Xie J
Sat Jul 01 00:00:00 EDT 2023
Metabolomic and transcriptomic studies of improvements in myocardial infarction due to Pycr1 deletion.
Journal of cellular and molecular medicine
Xue Z,Pan Y,Kong X,Zhang J,Wu D,Zhou B
Sun Jan 01 00:00:00 EST 2023
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
International journal of impotence research
Yao L,Cong R,Zhou X,Zhou X,Ji C,Wei X,Meng X,Song N
Wed Mar 15 00:00:00 EDT 2023
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Molecular medicine reports
Liu MH,Lin XL,Xiao LL
Sat Jul 01 00:00:00 EDT 2023
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Immunopharmacology and immunotoxicology
Wang X,Yang J,Wang W,Li Y,Yang Y
Sun Oct 01 00:00:00 EDT 2023
The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway.
Chinese medicine
Wan G,Chen Z,Lei L,Geng X,Zhang Y,Yang C,Cao W,Pan Z
Fri Feb 24 00:00:00 EST 2023
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Nature communications
Wu Y,Tang L,Huang H,Yu Q,Hu B,Wang G,Ge F,Yin T,Li S,Yu X
Fri Mar 10 00:00:00 EST 2023
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Brain sciences
Zhang ZH,Zhou XM,Zhang X
Thu May 18 00:00:00 EDT 2023
The involvement of let-7 in hCG-induced progesterone synthesis via regulating p27Kip1 and p21Cip1 expression.
Molecular and cellular endocrinology
Chen J,Liu K,Liu W,Yeung WS
Tue Aug 01 00:00:00 EDT 2023
NADPH-dependent ROS accumulation contributes to the impaired osteogenic differentiation of periodontal ligament stem cells under high glucose conditions.
Frontiers in endocrinology
Zhang YL,An Y,Sun LJ,Qu HL,Li X,He XT,Wu RX,Chen FM,Tian BM,Yin Y
Mon Jun 26 00:00:00 EDT 2023
IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye.
Investigative ophthalmology & visual science
Yang X,Zuo X,Zeng H,Liao K,He D,Wang B,Yuan J
Wed Mar 01 00:00:00 EST 2023
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
The Prostate
Chang T,Lian Z,Ma S,Liang Z,Ma X,Wen X,Wang Y,Liu R
Sat Apr 01 00:00:00 EDT 2023
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
Biological & pharmaceutical bulletin
Zhou H,Xu L,Shi Y,Gu S,Wu N,Liu F,Huang Y,Qian Z,Xue W,Wang X,Chen F
Thu Jan 05 00:00:00 EST 2023
Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1.
Respiratory research
Yang Z,Li P,Yuan Q,Wang X,Ma HH,Zhuan B
Fri Mar 24 00:00:00 EDT 2023
Cytotoxic Steroidal Saponins Containing a Rare Fructosyl from the Rhizomes of Paris polyphylla var. latifolia.
International journal of molecular sciences
Li TY,Du Y,Wang MC,Liu K,Liu Y,Cao Y,Wang YY,Chen WW,Qian XY,Qiu PC,Tang HF,Lu YY
Wed Apr 12 00:00:00 EDT 2023
Methylation-mediated silencing of EDN3 promotes cervical cancer proliferation, migration and invasion.
Frontiers in oncology
Zhu P,Li X,Liu Y,Xiong J,Yuan D,Chen Y,Luo L,Huang J,Wang B,Nie Q,Wang S,Dang L,Li S,Shu Y,Zhang W,Zhou H,Fan L,Li Q
Sun Feb 26 00:00:00 EST 2023
Ginsenoside Compound K Ameliorates Osteoarthritis by Inhibiting the Chondrocyte Endoplasmic Reticulum Stress-Mediated IRE1α-TXNIP-NLRP3 Axis and Pyroptosis.
Journal of agricultural and food chemistry
Tian Y,Feng X,Zhou Z,Qin S,Chen S,Zhao J,Hou J,Liu D
Wed Jan 25 00:00:00 EST 2023
Identification of MAP Kinase Kinase 3 as a protein target of myricetin in non-small cell lung cancer cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gu L,Li Z,Zhang X,Chen M,Zhang X
Mon May 01 00:00:00 EDT 2023
High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1-AMPK-ACC Pathway.
Cancers
Zhang M,Cui J,Chen H,Wang Y,Kuai X,Sun S,Tang Q,Zong F,Chen Q,Wu J,Wu S
Sun Apr 23 00:00:00 EDT 2023
The Protective Role of Scorias spongiosa Polysaccharide-Based Microcapsules on Intestinal Barrier Integrity in DSS-Induced Colitis in Mice.
Foods (Basel, Switzerland)
Xu Y,Feng H,Zhang Z,Zhang Q,Tang J,Zhou J,Wang Y,Peng W
Fri Feb 03 00:00:00 EST 2023
Histone mRNA polyadenylation-mediated inflammation underlies various virus infections and cancers.
Journal of medical virology
Guo M,Zhu J,Hu Z,Wang Q,Songyang Z,Xiong Y
Thu Jun 01 00:00:00 EDT 2023
Protective Mechanism of Ethyl Gallate against Intestinal Ischemia-Reperfusion Injury in Mice by in Vivo and in Vitro Studies Based on Transcriptomics.
Chemistry & biodiversity
Fan S,Feng X,Li K,Li B,Diao Y
Sun Jan 01 00:00:00 EST 2023
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Bioactive materials
Sun H,Xu J,Wang Y,Shen S,Xu X,Zhang L,Jiang Q
Thu Jun 01 00:00:00 EDT 2023
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Theriogenology
Xi H,Hu Z,Han S,Liu X,Wang L,Hu J
Sun Jan 01 00:00:00 EST 2023
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Current issues in molecular biology
Huang YK,Chang KC,Li CY,Lieu AS,Lin CL
Thu Apr 13 00:00:00 EDT 2023
Involvement of Galectin-3 in neurocognitive impairment in obstructive sleep apnea via regulating inflammation and oxidative stress through NLRP3.
Sleep medicine
Zong D,Liu X,Shen C,Liu T,Ouyang R
Sun Jan 01 00:00:00 EST 2023
miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation.
Redox biology
Wang X,Yang J,Li H,Mu H,Zeng L,Cai S,Su P,Li H,Zhang L,Xiang W
Thu Jun 01 00:00:00 EDT 2023
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Cell death & disease
Zheng G,Su Y,Wei L,Yao Y,Wang Y,Luo X,Wang X,Ruan XZ,Li D,Chen Y
Thu Apr 06 00:00:00 EDT 2023
Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.
International journal of molecular sciences
Yuan Y,Zhu Y,Li Y,Li X,Jiao R,Bai W
Tue Feb 07 00:00:00 EST 2023
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Cell death discovery
Tang S,Wu X,Dai Q,Li Z,Yang S,Liu Y,Yi B,Wang J,Liao Q,Zhang W,Zhang H
Fri May 12 00:00:00 EDT 2023
Lyn attenuates sepsis-associated acute kidney injury by inhibition of phospho-STAT3 and apoptosis.
Biochemical pharmacology
Li N,Lin G,Zhang H,Sun J,Gui M,Liu Y,Li W,Zhan Z,Li Y,Pan S,Liu J,Tang J
Mon May 01 00:00:00 EDT 2023
Platycodin D suppresses proliferation, migration, and invasion of human glioblastoma cells through regulation of Skp2.
European journal of pharmacology
Li H,Ouyang J,Liu R
Mon Jun 05 00:00:00 EDT 2023
Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.
Materials today. Bio
Gui X,Zhang H,Zhang R,Li Q,Zhu W,Nie Z,Zhao J,Cui X,Hao W,Wen X,Shen W,Song H
Sat Apr 01 00:00:00 EDT 2023
HIV-1 Infection Promotes Cholesterol Aggregation by Inducing miR-33b-5p to Suppress ABCA1 Expression.
AIDS research and human retroviruses
You Q,Qiao J,Peng Q,Li W,Li J,Hu S,Shu Z,Sun B
Fri Sep 01 00:00:00 EDT 2023
The Bcr-Abl inhibitor DCC-2036 inhibits necroptosis and ameliorates osteoarthritis by targeting RIPK1 and RIPK3 kinases.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Piao L,Wu D,Rui C,Yang Y,Liu S,Liu J,Jin Z,Zhang H,Feng X,Bai L
Mon May 01 00:00:00 EDT 2023
Comparative analysis of two new zebrafish models: The cyp1a low-expression line and cyp1a knockout line under PAHs exposure.
Gene
Xie S,Feng Y,Zhou A,Lu Z
Thu Jun 15 00:00:00 EDT 2023
SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma.
iScience
Li W,Xu N,Meng X,Yuan H,Yu T,Miao Q,Yang H,Hai B,Xiao W,Zhang X
Fri Jan 20 00:00:00 EST 2023
Effects of lactate on metabolism and differentiation of CD4+T cells.
Molecular immunology
Zhang YT,Xing ML,Fang HH,Li WD,Wu L,Chen ZP
Wed Feb 01 00:00:00 EST 2023
Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair.
Reproductive sciences (Thousand Oaks, Calif.)
Huang X,Liao J,Feng F,Chen S,Liao E,Li D,Dai X,Dong J,Shao Y
Thu Jun 01 00:00:00 EDT 2023
iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation.
EMBO molecular medicine
Tristán-Noguero A,Fernández-Carasa I,Calatayud C,Bermejo-Casadesús C,Pons-Espinal M,Colini Baldeschi A,Campa L,Artigas F,Bortolozzi A,Domingo-Jiménez R,Ibáñez S,Pineda M,Artuch R,Raya Á,García-Cazorla À,Consiglio A
Wed Mar 08 00:00:00 EST 2023
A Recombinant Parathyroid Hormone-Related Peptide Locally Applied in Osteoporotic Bone Defect.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang Y,Hu Y,Lan S,Chen Z,Zhang Y,Guo X,Cai L,Li J
Tue Aug 01 00:00:00 EDT 2023
Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy.
Molecules (Basel, Switzerland)
Shang J,Lin N,Peng R,Jiang N,Wu B,Xing B,Lin S,Xu X,Lu H
Tue Jan 17 00:00:00 EST 2023
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Han Y,Zheng Y,You J,Han Y,Lu X,Wang X,Shi C,Zhu W
Sun Oct 01 00:00:00 EDT 2023
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
Biomedical and environmental sciences : BES
Wen SY,Liu YT,Wei BY,Ma JQ,Chen YY
Mon Mar 20 00:00:00 EDT 2023
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
Journal of thoracic disease
Wang Y,Li C,Wu Z,Dai Y,Liu L,Chen L
Fri Mar 31 00:00:00 EDT 2023
Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance.
Journal of advanced research
Hu HF,Gao GB,He X,Li YY,Li YJ,Li B,Pan Y,Wang Y,He QY
Fri Sep 01 00:00:00 EDT 2023
Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
Journal of translational medicine
Yang K,Qiu T,Zhou J,Gong X,Zhang X,Lan Y,Zhang Z,Ji Y
Mon Feb 06 00:00:00 EST 2023
PM2.5 induces autophagy-dependent ferroptosis by endoplasmic reticulum stress in SH-SY5Y cells.
Journal of applied toxicology : JAT
Guo CC,Xu ZM,Lyu Y,Li XH,Li ZF,He H,Tian FJ,Zheng JP
Sat Jul 01 00:00:00 EDT 2023
The molecular mechanism of miR-96-5p in the pathogenesis and treatment of polycystic ovary syndrome.
Translational research : the journal of laboratory and clinical medicine
Liu Y,Zhang S,Chen L,Huang X,Wang M,Ponikwicka-Tyszko D,Rahman NA,Wolczynski S,Yao B,Li X
Thu Jun 01 00:00:00 EDT 2023
Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.
Journal of physiology and biochemistry
Li S,Ni Y,Li C,Xiang Q,Zhao Y,Xu H,Huang W,Wang Y,Wang Y,Zhan J,Liu Y
Wed Feb 01 00:00:00 EST 2023
Submersion and hypoxia inhibit alveolar epithelial Na+ transport through ERK/NF-κB signaling pathway.
Respiratory research
Zhou W,Hou Y,Yu T,Wang T,Ding Y,Nie H
Mon Apr 24 00:00:00 EDT 2023
Cuproptosis is involved in copper-induced hepatotoxicity in chickens.
The Science of the total environment
Zhong G,Li L,Li Y,Ma F,Liao J,Li Y,Zhang H,Pan J,Hu L,Tang Z
Sat Mar 25 00:00:00 EDT 2023
Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5.
Brain, behavior, and immunity
Wang X,Lin C,Jin S,Wang Y,Peng Y,Wang X
Sat Jul 01 00:00:00 EDT 2023
The role of selenoprotein M in nickel-induced pyroptosis in mice spleen tissue via oxidative stress.
Environmental science and pollution research international
Ma W,Liu Y,Xu L,Gai X,Sun Y,Qiao S,Liu P,Liu Q,Zhang Z
Wed Mar 01 00:00:00 EST 2023
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Journal of ethnopharmacology
Wu L,Fan Z,Gu L,Liu J,Cui Z,Yu B,Kou J,Li F
Tue May 23 00:00:00 EDT 2023
Effects of heat shock protein 90 on complement activation in myocardial ischemia/reperfusion injury after pioglitazone preconditioning.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Wang D,He S,Zhong G,Meng J,Bi Q,Tu R
Fri Dec 01 00:00:00 EST 2023
Integrated Machine Learning and Bioinformatic Analyses Constructed a Network Between Mitochondrial Dysfunction and Immune Microenvironment of Periodontitis.
Inflammation
Chen H,Peng L,Wang Z,He Y,Zhang X
Sun Oct 01 00:00:00 EDT 2023
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zou T,Xie F,Liang P,Chen J,Wang Z,Du M,You J
Sun Jan 01 00:00:00 EST 2023
A novel autophagy-related gene signature associated with prognosis and immune microenvironment in ovarian cancer.
Journal of ovarian research
Yang J,Wang C,Zhang Y,Cheng S,Wu M,Gu S,Xu S,Wu Y,Wang Y
Sat Apr 29 00:00:00 EDT 2023
Bach1 modulates AKT3 transcription to participate in hyperglycaemia-mediated EndMT in vascular endothelial cells.
Clinical and experimental pharmacology & physiology
Meng Z,Shen W,Yu L,Tong F,He H,Hu Y,Wu W,Liu J
Thu Jun 01 00:00:00 EDT 2023
GPR35 antagonist CID-2745687 attenuates anchorage-independent cell growth by inhibiting YAP/TAZ activity in colorectal cancer cells.
Frontiers in pharmacology
Otkur W,Liu X,Chen H,Li S,Ling T,Lin H,Yang R,Xia T,Qi H,Piao HL
Sun Apr 30 00:00:00 EDT 2023
Nicaraven protects against endotoxemia-induced inflammation and organ injury through modulation of AMPK/Sirt1 signaling in macrophages.
European journal of pharmacology
Zha D,Yang Y,Huang X,Wang Z,Lin H,Yang L,Xu L,Wu Y,Huang H,Wang Y,Xin Z,Wu X,Xiao YF,Li TS,Deng KY,Xin HB,Qian Y
Fri May 05 00:00:00 EDT 2023
Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer.
Research (Washington, D.C.)
Li Y,Cen Y,Tu M,Xiang Z,Tang S,Lu W,Zhang H,Xu J
Mon Mar 20 00:00:00 EDT 2023
Degradation of Perineuronal Nets in the Cerebellar Interpositus Nucleus Ameliorated Social Deficits in Shank3-deficient Mice.
Neuroscience
Liu P,Zhao Y,Xiong W,Pan Y,Zhu M,Zhu X
Fri Feb 10 00:00:00 EST 2023
Atf4 regulates angiogenic differences between alveolar bone and long bone macrophages by regulating M1 polarization, based on single-cell RNA sequencing, RNA-seq and ATAC-seq analysis.
Journal of translational medicine
Gu L,Wang Z,Gu H,Wang H,Liu L,Zhang WB
Tue Mar 14 00:00:00 EDT 2023
GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis.
Experimental hematology & oncology
Guo W,Gong Q,Zong X,Wu D,Li Y,Xiao H,Song J,Zhang S,Fu S,Feng Z,Zhuang L
Tue Jan 31 00:00:00 EST 2023
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Acta biomaterialia
Zhang T,Wang Y,Li R,Xin J,Zheng Z,Zhang X,Xiao C,Zhang S
Wed Mar 01 00:00:00 EST 2023
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
Archives of oral biology
Lin X,Ding JM,Zheng XZ,Chen JG
Wed Mar 01 00:00:00 EST 2023
Peripheral BDNF Regulates Somatosensory-Sympathetic Coupling in Brachial Plexus Avulsion-Induced Neuropathic Pain.
Neuroscience bulletin
Xian H,Guo H,Liu YY,Zhang JL,Hu WC,Yu MJ,Zhao R,Xie RG,Zhang H,Cong R
Fri Dec 01 00:00:00 EST 2023
HSF4 promotes tumor progression of colorectal cancer by transactivating c-MET.
Molecular and cellular biochemistry
Zhang W,Zhang X,Cheng P,Yue K,Tang M,Li Y,Guo Q,Zhang Y
Mon May 01 00:00:00 EDT 2023
Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
The Journal of biological chemistry
Shang Q,Pan C,Zhang X,Yang T,Hu T,Zheng L,Cao S,Feng C,Hu X,Chai X,Wang J,Fang Q
Sun Jan 01 00:00:00 EST 2023
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Journal of virology
Cheng M,Kanyema MM,Sun Y,Zhao W,Lu Y,Wang J,Li X,Shi C,Wang J,Wang N,Yang W,Jiang Y,Huang H,Yang G,Zeng Y,Wang C,Cao X
Tue Feb 28 00:00:00 EST 2023
An early-onset SLE patient with a novel paternal inherited BACH2 mutation.
Journal of clinical immunology
Zhou L,Sun G,Chen R,Chen J,Fang S,Xu Q,Tang W,Dai R,Zhang Z,An Y,Tang X,Zhao X
Tue Aug 01 00:00:00 EDT 2023
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Tissue & cell
Cui Z,Qin R,Feng J,Liu Y,Zhou X,Qin X,Li Y,Zhang Z,He X
Tue Aug 01 00:00:00 EDT 2023
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang Y,Qin X,Yang Y,Li J,Li X,Zou X,Huang Z,Huang S
Sat Jul 01 00:00:00 EDT 2023
Effects of long-term resveratrol treatment in hypothalamic astrocyte cultures from aged rats.
Molecular and cellular biochemistry
Sovrani V,Bobermin LD,Santos CL,Brondani M,Gonçalves CA,Leipnitz G,Quincozes-Santos A
Thu Jun 01 00:00:00 EDT 2023
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Behavioural brain research
Tong T,Chen Y,Hao C,Shen J,Chen W,Cheng W,Yan S,Li J,Li Y,Gulizhaerkezi T,Zeng J,Meng X
Sat Aug 05 00:00:00 EDT 2023
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Artificial organs
Wei S,Cheng X,Li J,Zhai K,Huang J,Wang S,Li Y,Liu D
Sat Jul 01 00:00:00 EDT 2023
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Cai Z,Shen Z,Zhao J,Zhang H,Guo Z,Xia Q,Liang H,Liu J,Tan L,Sheng H,Zhu S
Thu Jun 01 00:00:00 EDT 2023
Microglial NLRP3 inflammasome activation mediates diabetes-induced depression-like behavior via triggering neuroinflammation.
Progress in neuro-psychopharmacology & biological psychiatry
Su WJ,Li JM,Zhang T,Cao ZY,Hu T,Zhong SY,Xu ZY,Gong H,Jiang CL
Wed Aug 30 00:00:00 EDT 2023
Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.
Cell death & disease
Li Y,Wang W,Hou X,Huang W,Zhang P,He Y,Wang B,Duan Q,Mao F,Guo D
Fri Jan 13 00:00:00 EST 2023
E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis.
Clinical epigenetics
Li J,Wang J,Wang Y,Zhao X,Su T
Tue Jan 31 00:00:00 EST 2023
Staphylococci planktonic and biofilm environments differentially affect osteoclast formation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Seebach E,Kraus FV,Elschner T,Kubatzky KF
Sat Jul 01 00:00:00 EDT 2023
TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.
Journal of virology
Li XQ,Zeng L,Liang DG,Qi YL,Yang GY,Zhong K,Chu BB,Wang J
Thu Jun 29 00:00:00 EDT 2023
Acupuncture exerts preventive effects in rats of chronic unpredictable mild stress: The involvement of inflammation in amygdala and brain-spleen axis.
Biochemical and biophysical research communications
Chen W,Chen Y,Cheng W,Li P,Shen J,Tong T,Lai L,Yan S,Huang Z,Li J,Huang S,Meng X
Sun Feb 26 00:00:00 EST 2023
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Biology
Ma Z,Liu Z,Li X,Zhang H,Han D,Xiong W,Zhou H,Yang X,Zeng Q,Ren H,Xu D
Tue Apr 11 00:00:00 EDT 2023
A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis.
Cancer cell international
Hao R,Zhang L,Si Y,Zhang P,Wang Y,Li B,Hu J,Qi Y
Sat Mar 25 00:00:00 EDT 2023
Promotion of intestinal epithelial cell apoptosis by enterotoxigenic Escherichia coli via PKA-mediated inhibition of mTORC1 activation.
Microbes and infection
Zheng Y,Wang G,Li R,Geng H,Lei X,Chen L,Wu S,Yao J,Deng L
Thu Jun 01 00:00:00 EDT 2023
Puerarin protects against sepsis-associated encephalopathy by inhibiting NLRP3/Caspase-1/GSDMD pyroptosis pathway and reducing blood-brain barrier damage.
European journal of pharmacology
Zhou S,Li Y,Hong Y,Zhong Z,Zhao M
Sat Apr 15 00:00:00 EDT 2023
Targeting lncRNA DDIT4-AS1 Sensitizes Triple Negative Breast Cancer to Chemotherapy via Suppressing of Autophagy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jiang T,Zhu J,Jiang S,Chen Z,Xu P,Gong R,Zhong C,Cheng Y,Sun X,Yi W,Yang J,Zhou W,Cheng Y
Thu Jun 01 00:00:00 EDT 2023
LncRNA SLC25A21-AS1 increases the chemosensitivity and inhibits the progression of ovarian cancer by upregulating the expression of KCNK4.
Functional & integrative genomics
Huang K,Chen X,Geng Z,Xiong X,Cong Y,Pan X,Liu S,Ge L,Xu J,Jia X
Thu Mar 30 00:00:00 EDT 2023
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
Journal of cancer research and clinical oncology
Li Y,Fang Z,Ge S,Li J,Qu L,Shi X,Zhang W,Sun Y,Ren S,Wang L
Tue Aug 01 00:00:00 EDT 2023
The NLRP3 inflammasome recognizes alpha-2 and alpha-7.3 giardins and decreases the pathogenicity of Giardia duodenalis in mice.
Parasites & vectors
Zhao P,Li J,Li X,Dong J,Wang X,Zhang N,Li S,Sun M,Zhang X,Wang Z,Liang M,Li Y,Cao L,Gong P
Fri Mar 03 00:00:00 EST 2023
APEX1 predicts poor prognosis of gallbladder cancer and affects biological properties of CD133+ GBC-SD cells via upregulating Jagged1.
Journal of Cancer
Wu Z,Liu Z,Sun Y,Yuan Y,Zou Q,Wen Y,Luo J,Liu R
Thu Jun 08 00:00:00 EDT 2023
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
International journal of oncology
Miao Y,Wang X,Lai Y,Huang Y,Yin H,Meng X,Liu H,Hou R,Lin W,Zhang X,Zhang X,Chai BC,Zhang F,Guo L,Yang S
Sat Jul 01 00:00:00 EDT 2023
Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction.
Neuromodulation : journal of the International Neuromodulation Society
He Y,Sun Z,Jiang J,Yin X,Han J,Zhang Y,Zheng L
Sun Jan 01 00:00:00 EST 2023
The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets.
Journal of natural products
Ren Y,Kaweesa EN,Tian L,Wu S,Sydara K,Xayvue M,Moore CE,Soejarto DD,Cheng X,Yu J,Burdette JE,Kinghorn AD
Fri Jun 23 00:00:00 EDT 2023
Long non-coding RNA LINC00707, a prognostic marker, regulates cell proliferation, apoptosis, and EMT in esophageal squamous cell carcinoma.
American journal of translational research
Gao N,Jiang G,Gao Z,Cui M,Li J,Liu H,Fan T
Fri May 19 00:00:00 EDT 2023
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Cell death & disease
Wang G,Qin S,Chen L,Geng H,Zheng Y,Xia C,Yao J,Deng L
Tue Apr 25 00:00:00 EDT 2023
A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations.
Frontiers in aging neuroscience
Allen SP,Al Sultan A,Kabucho Kibirige E,Tonkiss E,Hamer KJ,Castelli LM,Lin YH,Roscoe S,Stefanidis N,Mead RJ,Highley JR,Cooper-Knock J,Hautbergue GM,Heath PR,Kirby J,Shaw PJ
Wed May 31 00:00:00 EDT 2023
Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia.
Acta pharmaceutica Sinica. B
Feng Y,Han Y,Hu A,Qu Y,Hu Y,Wu H,Wang X,He L
Wed Feb 01 00:00:00 EST 2023
E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways.
International journal of molecular sciences
Huang TT,Chen CM,Lin SS,Lan YW,Cheng HC,Choo KB,Wang CC,Huang TH,Chong KY
Wed May 31 00:00:00 EDT 2023
Resveratrol and Dulaglutide ameliorate adiposity and liver dysfunction in rats with diet-induced metabolic syndrome: Role of SIRT-1 / adipokines / PPARγ and IGF-1.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences
Shamardl HAMA,Ibrahim NA,Merzeban DH,Elamir AM,Golam RM,Elsayed AM
Thu Jun 01 00:00:00 EDT 2023
25-hydroxycholesterol inhibits human papillomavirus infection in cervical epithelial cells by perturbing cytoskeletal remodeling.
Journal of medical virology
Li B,Hua C,Tian P,Sha Y,Zhang L,Wang Q,Lu L,Jiang S,Sui L
Thu Jun 01 00:00:00 EDT 2023
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Mediators of inflammation
Liu Z,Fan Z,Wang R,Li X,Chen H,Wang J
Wed Mar 15 00:00:00 EDT 2023
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Journal of ethnopharmacology
Zhang X,Zhao L,Xiang S,Sun Y,Wang P,Chen JJ,Teo BS,Xie Z,Zhang Z,Xu J
Wed May 10 00:00:00 EDT 2023
Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling.
BMC cancer
Gao J,Hu J,Yu F,Wang C,Sheng D,Liu W,Hu A,Yu K,Xiao X,Kuang Y,Zacksenhaus E,Gajendran B,Ben-David Y
Tue Apr 04 00:00:00 EDT 2023
CXCL11 negatively regulated by MED19 favours antitumour immune infiltration in breast cancer.
Cytokine
Zhang X,Wu J,Hu C,Zheng X,Guo Z,Li L
Wed Feb 01 00:00:00 EST 2023
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
Molecular biology reports
Zhang L,Zhou T,Ji Q,He L,Lan Y,Ding L,Li L,Wang Z
Wed Mar 01 00:00:00 EST 2023
Hypoxia Inhibits Cell Cycle Progression and Cell Proliferation in Brain Microvascular Endothelial Cells via the miR-212-3p/MCM2 Axis.
International journal of molecular sciences
Shi Q,Li S,Lyu Q,Zhang S,Bai Y,Ma J
Wed Feb 01 00:00:00 EST 2023
VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4.
Cancer gene therapy
Shi X,Zhao P,Zhao G
Wed Feb 01 00:00:00 EST 2023
Exogenous H2S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions.
International journal of molecular sciences
Liu N,Li M,Liu S,Kang J,Chen L,Huang J,Wang Y,Chen H,Zhang W
Sat Jan 14 00:00:00 EST 2023
Citrus peel ameliorates mucus barrier damage in HFD-fed mice.
The Journal of nutritional biochemistry
Han P,Yu Y,Zhang L,Ruan Z
Wed Feb 01 00:00:00 EST 2023
m6A reader HNRNPA2B1 destabilization of ATG4B regulates autophagic activity, proliferation and olaparib sensitivity in breast cancer.
Experimental cell research
Zheng R,Yu Y,Lv L,Zhang Y,Deng H,Li J,Zhang B
Wed Mar 01 00:00:00 EST 2023
BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway.
International journal of oncology
Shan F,Shen S,Wang X,Chen G
Sat Apr 01 00:00:00 EDT 2023
NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia-reperfusion injury.
Chemico-biological interactions
Lu J,Wang M,Chen Y,Song H,Wen D,Tu J,Guo Y,Liu Z
Thu Jan 05 00:00:00 EST 2023
Turnip crinkle virus-encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection.
Molecular plant pathology
Liu L,Wang H,Fu Y,Tang W,Zhao P,Ren Y,Liu Z,Wu K,Zhang X
Wed Feb 01 00:00:00 EST 2023
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
Translational research : the journal of laboratory and clinical medicine
An X,Wu W,Yang L,Dong J,Liu B,Guo J,Chen J,Guo B,Cao W,Jiang Q
Fri Sep 01 00:00:00 EDT 2023
Downregulation of lncRNA SLC7A11-AS1 decreased the NRF2/SLC7A11 expression and inhibited the progression of colorectal cancer cells.
PeerJ
Wang T,Liang S,Li Y,Wang X,Wang H,Guo J,Li M
Fri Apr 21 00:00:00 EDT 2023
Low dose TGF-β1 can improve vohwinkel syndrome by promoting the proliferation of keratinocytes.
Acta histochemica
Ling X,Dong S,Zhang L
Wed Feb 01 00:00:00 EST 2023
FUNDC1 modulates mitochondrial defects and pancreatic β-cell dysfunction under lipotoxicity.
Biochemical and biophysical research communications
Tong B,Zhang Z,Li X,Liu J,Wang H,Song L,Feng J,Dai Z,Xu Y
Sun Sep 10 00:00:00 EDT 2023
Montelukast Inhibits Lung Cancer Cell Migration by Suppressing Cysteinyl Leukotriene Receptor 1 Expression In vitro.
Current pharmaceutical biotechnology
Chen Y,Zhang J,Wei S
Thu Jun 01 00:00:00 EDT 2023
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang Q,Ren J,Wang F,Li M,Pan M,Zhang H,Qu F
Sun Jan 01 00:00:00 EST 2023
Mesenchymal stem cells ameliorate cisplatin-induced acute kidney injury via let-7b-5p.
Cell and tissue research
Wang SY,Xu Y,Hong Q,Chen XM,Cai GY
Mon May 01 00:00:00 EDT 2023
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling.
The Journal of biological chemistry
Iwano T,Sobajima T,Takeda S,Harada A,Yoshimura SI
Wed Mar 01 00:00:00 EST 2023
Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats.
Journal of ethnopharmacology
Guo C,Zhou X,Wang X,Wang H,Liu J,Wang J,Lin X,Lei S,Yang Y,Liu K,Long H,Zhou D
Wed Jun 28 00:00:00 EDT 2023
Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer.
Frontiers in oncology
Chen J,Liu Z,Wu Z,Li W,Tan X
Wed May 31 00:00:00 EDT 2023
Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu D,Liang CH,Huang B,Zhuang X,Cui W,Yang L,Yang Y,Zhang Y,Fu X,Zhang X,Du L,Gu W,Wang X,Yin C,Chai R,Chu B
Wed Feb 01 00:00:00 EST 2023
Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps.
Molecular immunology
Tang B,Tu J,Zhang M,Zhang Z,Yu J,Shen L,Luo Q,Ye J
Sat Jul 01 00:00:00 EDT 2023
AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
Experimental neurology
Wang C,Chang Y,Zhu J,Wu Y,Jiang X,Zheng S,Li G,Ma R
Mon May 01 00:00:00 EDT 2023
Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression.
PLoS genetics
Qin S,Wang G,Chen L,Geng H,Zheng Y,Xia C,Wu S,Yao J,Deng L
Wed Feb 01 00:00:00 EST 2023
Jiang-Tang-San-Huang pill alleviates type 2 diabetes mellitus through modulating the gut microbiota and bile acids metabolism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tawulie D,Jin L,Shang X,Li Y,Sun L,Xie H,Zhao J,Liao J,Zhu Z,Cui H,Wen W
Mon May 01 00:00:00 EDT 2023
Shoutai Wan regulates glycolysis imbalance at the maternal-fetal interface in threatened abortion mice.
Journal of ethnopharmacology
Zhang L,Wang S,Ma Y,Song Y,Li D,Liang X,Hao Y,Jiang M,Lv J,Du H
Thu Aug 10 00:00:00 EDT 2023
Mechanism of the HIF-1α/VEGF/VEGFR-2 pathway in the proliferation and apoptosis of human haemangioma endothelial cells.
International journal of experimental pathology
Zhang W,Sun L,Gao H,Wang S
Sun Oct 01 00:00:00 EDT 2023
Effect of botanical drugs in improving symptoms of hypertensive nephropathy: Analysis of real-world data, retrospective cohort, network, and experimental assessment.
Frontiers in pharmacology
Huan JM,Ma XT,Li SY,Hu DQ,Chen HY,Wang YM,Su XY,Su WG,Wang YF
Tue Apr 25 00:00:00 EDT 2023
Comprehensive Genomic Profiling Identifies FAT1 as a Negative Regulator of EMT, CTCs, and Metastasis of Hepatocellular Carcinoma.
Journal of hepatocellular carcinoma
Huang ZL,Zhang PB,Zhang JT,Li F,Li TT,Huang XY
Wed Mar 15 00:00:00 EDT 2023
Pomegranate Peel Extract Sensitizes Hepatocellular Carcinoma Cells to Ionizing Radiation, Induces Apoptosis and Inhibits MAPK, JAK/STAT3, β-Catenin/NOTCH, and SOCS3 Signaling.
Integrative cancer therapies
Elbakry MMM,ElBakary NM,Hagag SA,Hemida EHA
Tue Jan 31 00:00:00 EST 2023
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Journal of orthopaedic translation
Wang P,Yang C,Lu J,Ren Y,Goltzman D,Miao D
Mon May 01 00:00:00 EDT 2023
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
Environmental toxicology
Li T,Liu X,Long X,Li Y,Xiang J,Lv Y,Zhao X,Shi S,Chen W
Sun Oct 01 00:00:00 EDT 2023
O-GlcNAcylation enhances Reticulon 2 protein stability and its promotive effects on gastric cancer progression.
Cellular signalling
Wang G,Xu Z,Sun J,Liu B,Ruan Y,Gu J,Song S
Tue Aug 01 00:00:00 EDT 2023
Circular RNA circ-TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR-452-5p/DAG1 axis.
Molecular oncology
Xu R,Ding P,Zhao X,Li Z,Liu F,Gu L,Zheng Y,Sang M,Meng L
Sat Jul 01 00:00:00 EDT 2023
TRIM7 inhibits encephalomyocarditis virus replication by activating interferon-β signaling pathway.
Veterinary microbiology
Li M,Yan J,Zhu H,Guo C,Jiang X,Gao Y,Liu X,Jiang P,Bai J
Thu Jun 01 00:00:00 EDT 2023
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-[Formula: see text]B Pathways.
The American journal of Chinese medicine
Li Q,Li Z,Liu C,Xu M,Li T,Wang Y,Feng J,Yin X,Du X,Lu C
Mon Jun 19 00:00:00 EDT 2023
The Effect of an Essential Oil Blend on Growth Performance, Intestinal Health, and Microbiota in Early-Weaned Piglets.
Nutrients
Shao Y,Peng Q,Wu Y,Peng C,Wang S,Zou L,Qi M,Peng C,Liu H,Li R,Xiong X,Yin Y
Sat Jan 14 00:00:00 EST 2023
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Journal of ethnopharmacology
Duan J,Li Z,Liu E,Long H,Chen L,Yang S
Wed Nov 15 00:00:00 EST 2023
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
European journal of nutrition
Wang Y,Chen X,Baker JS,Davison GW,Xu S,Zhou Y,Bao X
Sat Apr 01 00:00:00 EDT 2023
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
International immunopharmacology
Huang B,Hu G,Zong X,Yang S,He D,Gao X,Liu D
Wed Feb 01 00:00:00 EST 2023
cPKCγ Inhibits Caspase-9-Initiated Neuronal Apoptosis in an Ischemia Reperfusion Model In Vitro Through p38 MAPK-p90RSK-Bad Pathway.
Neurochemical research
Wei HP,Peng ZF,Shao KM,Zhang PH,Chen L,Hu JA,Chai H,Liu JM
Wed Feb 01 00:00:00 EST 2023
Folate inhibits lipid deposition via the autophagy pathway in chicken hepatocytes.
Poultry science
Du ZQ,Pang YQ,Zhang Y,Wang L,Zhang R,Li H,Yang CX
Wed Feb 01 00:00:00 EST 2023
Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma.
Journal of oncology
Pan ST,Ye FF,Huang G,Qiu JX
Fri Feb 24 00:00:00 EST 2023
NMR-Based Metabolic Profiling of the Effects of α-Ketoglutarate Supplementation on Energy-Deficient C2C12 Myotubes.
Molecules (Basel, Switzerland)
Li Y,Zhang S,Huang C,Lin D
Sun Apr 30 00:00:00 EDT 2023
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Human cell
Zhang F,Zou H,Li X,Liu J,Xie Y,Chen M,Yu J,Wu X,Guo B
Mon May 01 00:00:00 EDT 2023
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication via Inflammation and Fibrosis Inhibition in Mice.
Chemical & pharmaceutical bulletin
Ning X,Ni Y,Cao J,Zhang H
Tue Apr 04 00:00:00 EDT 2023
Lysosome-related exosome secretion mediated by miR-26b / Rab31 pathway was associated with the proliferation and migration of MCF-7 cells treated with BPA.
Ecotoxicology and environmental safety
Chen Y,Hu Z,Tang M,Huang F,Xiong Y,Ouyang D,He J,He S,Xian H,Hu D
Wed Mar 01 00:00:00 EST 2023
Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats.
BMC neuroscience
Zhou J,Zhang C,Fang X,Zhang N,Zhang X,Zhu Z
Sat Jan 28 00:00:00 EST 2023
Hydrogen peroxide and iron ions can modulate lipid peroxidation, apoptosis, and the cell cycle, but do not have a significant effect on DNA double-strand break.
Biochemical and biophysical research communications
Yang H,Tai F,Wang T,Zheng X,Ge C,Qin Y,Fu H
Sun Apr 09 00:00:00 EDT 2023
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
International immunopharmacology
Zhang M,Xiong Y,Tu J,Tang B,Zhang Z,Yu J,Shen L,Luo Q,Ye J
Mon May 01 00:00:00 EDT 2023
PPARα Inhibits Astrocyte Inflammation Activation by Restoring Autophagic Flux after Transient Brain Ischemia.
Biomedicines
Luo D,Ye W,Chen L,Yuan X,Zhang Y,Chen C,Jin X,Zhou Y
Tue Mar 21 00:00:00 EDT 2023
Colocalization of Chikungunya Virus with Its Receptor MXRA8 during Cell Attachment, Internalization, and Membrane Fusion.
Journal of virology
Feng F,Bouma EM,Hu G,Zhu Y,Yu Y,Smit JM,Diamond MS,Zhang R
Wed May 31 00:00:00 EDT 2023
Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer.
Cancers
Huang Z,Zhu S,Han Z,Li C,Liang J,Wang Y,Zhang S,Zhang J
Wed Jan 25 00:00:00 EST 2023
ABCG2 plays a central role in the dysregulation of 25-hydrovitamin D in Crohn's disease.
The Journal of nutritional biochemistry
Peng J,Song X,Zhu F,Zhang C,Xia J,Zou D,Liu J,Yin F,Yin L,Guo H,Liu J
Tue Aug 01 00:00:00 EDT 2023
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Hu Y,Yan Z,He Y,Li Y,Li M,Li Y,Zhang D,Zhao Y,Ommati MM,Wang J,Huo M,Wang J
Sat Apr 01 00:00:00 EDT 2023
Effect of arsenic stress on the intestinal structural integrity and intestinal flora abundance of Cyprinus carpio.
Frontiers in microbiology
Shi X,Xu W,Che X,Cui J,Shang X,Teng X,Jia Z
Sun May 14 00:00:00 EDT 2023
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Journal of agricultural and food chemistry
Liu J,Fu L,Yin F,Yin L,Song X,Guo H,Liu J
Wed Jun 14 00:00:00 EDT 2023
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Journal of ethnopharmacology
Wu S,Tian C,Tu Z,Guo J,Xu F,Qin W,Chang H,Wang Z,Hu T,Sun X,Ning H,Li Y,Gou W,Hou W
Sat Jul 15 00:00:00 EDT 2023
Ribosomal protein L32 enhances hepatocellular carcinoma progression.
Cancer medicine
Hou G,Lu Z,Jiang J,Yang X
Mon May 01 00:00:00 EDT 2023
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Neurochemical research
Shen M,Zheng Y,Li G,Chen Y,Huang L,Wu J,Hong C
Wed Feb 01 00:00:00 EST 2023
LEM Domain Containing 1 Acts as a Novel Oncogene and Therapeutic Target for Triple-Negative Breast Cancer.
Cancers
Li X,Jiang S,Jiang T,Sun X,Guan Y,Fan S,Cheng Y
Fri May 26 00:00:00 EDT 2023
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cellular signalling
Qiu D,Song S,Chen N,Bian Y,Yuan C,Zhang W,Duan H,Shi Y
Tue Aug 01 00:00:00 EDT 2023
Endothelial progenitor cell-derived exosomes inhibit pulmonary artery smooth muscle cell in vitro proliferation and resistance to apoptosis by modulating the Mitofusin-2 and Ras-Raf-ERK1/2 signaling pathway.
European journal of pharmacology
Liu P,Gao S,Li Z,Pan S,Luo G,Ji Z
Thu Jun 15 00:00:00 EDT 2023
DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway.
Veterinary research
Xia X,Cheng A,Wang M,Ou X,Sun D,Zhang S,Mao S,Yang Q,Tian B,Wu Y,Huang J,Gao Q,Jia R,Chen S,Liu M,Zhao XX,Zhu D,Yu Y,Zhang L
Thu Jan 26 00:00:00 EST 2023
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Drug delivery and translational research
Xiang X,Chen J,Jiang T,Yan C,Kang Y,Zhang M,Xiang K,Guo J,Jiang G,Wang C,Yang X,Chen Z
Fri Sep 01 00:00:00 EDT 2023
KLF2 is a clinical diagnostic and treatment biomarker of breast cancer.
Frontiers in cell and developmental biology
Li YZ,Xie J,Wang RQ,Gao XQ,Liu PJ,Liu J
Tue May 02 00:00:00 EDT 2023
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
International urology and nephrology
Wang Z,Yang Z,Qu C,Li J,Wang X
Tue Aug 01 00:00:00 EDT 2023
The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation.
Frontiers in molecular biosciences
Che H,Shao Z,Ding J,Gao H,Liu X,Chen H,Cai S,Ge J,Wang C,Wu J,Hao Y
Tue Apr 04 00:00:00 EDT 2023
Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R.
Neurochemical research
Zhou WM,Lei ZY,Shi YQ,Gong CY,Kai Z,Wei N,Wang LN,Zhang CJ,Zhang HH
Sun Oct 01 00:00:00 EDT 2023
Prognosis, immune microenvironment, and personalized treatment prediction in Rho GTPase-activating protein 4-mutant cervical cancer: Computer strategies for precision oncology.
Life sciences
Lu X,Ying Y,Zhang W,Zhang J,Li R,Wang W
Wed Feb 15 00:00:00 EST 2023
A novel circular RNA circNLRP3 alleviated ricin toxin-induced TNF-α production through sponging miR-221-5p.
Toxicon : official journal of the International Society on Toxinology
Chen W,Chang Y,Sun C,Xu M,Dong M,Zhao N,Wang Y,Zhang J,Xu N,Liu W
Wed Mar 01 00:00:00 EST 2023
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
European journal of pharmacology
Qiao N,An Z,Fu Z,Chen X,Tong Q,Zhang Y,Ren H
Thu Jun 15 00:00:00 EDT 2023
Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism.
mSphere
Mastrodomenico V,LoMascolo NJ,Firpo MR,Villanueva Guzman MDM,Zaporowski A,Mounce BC
Thu Jun 22 00:00:00 EDT 2023
Exercise induced meteorin-like protects chondrocytes against inflammation and pyroptosis in osteoarthritis by inhibiting PI3K/Akt/NF-κB and NLRP3/caspase-1/GSDMD signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu J,Jia S,Yang Y,Piao L,Wang Z,Jin Z,Bai L
Wed Feb 01 00:00:00 EST 2023
The Role of LincRNA-EPS/Sirt1/Autophagy Pathway in the Neuroprotection Process by Hydrogen against OGD/R-Induced Hippocampal HT22 Cells Injury.
Journal of personalized medicine
Li YH,Zhang S,Tang L,Feng J,Jia J,Chen Y,Liu L,Zhou J
Mon Apr 03 00:00:00 EDT 2023
Karyopherin Subunit Alpha 1 Enhances the Malignant Behaviors of Colon Cancer Cells via Promoting Nuclear Factor-κB p65 Nuclear Translocation.
Digestive diseases and sciences
Zhao L,Wu D,Qu Q,Li Z,Yin H
Sat Jul 01 00:00:00 EDT 2023
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages.
International journal of molecular medicine
Han Z,Ma J,Han Y,Yuan G,Jiao R,Meng A
Sat Apr 01 00:00:00 EDT 2023
PM2.5 mediates mouse testis Sertoli TM4 cell damage by reducing cellular NAD.
Toxicology mechanisms and methods
Xu P,Ren T,Yang Y
Sun Oct 01 00:00:00 EDT 2023
Repetitive transcranial magnetic stimulation alleviates glial activation through suppressing HMGB1/TLR4 pathway in a rat model of Parkinson's disease.
Molecular biology reports
Han C,Zhang X,Dou K,Yao W,Yao M,Wan Q,Xie A
Tue Aug 01 00:00:00 EDT 2023
IL-33/ST2 mediating systemic inflammation and neuroinflammation through NF-kB participated in the neurocognitive impairment in obstructive sleep apnea.
International immunopharmacology
Shen C,Liu X,Liu T,Ou Y,Ouyang R
Wed Feb 01 00:00:00 EST 2023
Disruption of COMMD1 accelerates diabetic atherosclerosis by promoting glycolysis.
Diabetes & vascular disease research
Zhang L,Li L,Li Y,Jiang H,Sun Z,Zang G,Qian Y,Shao C,Wang Z
Thu Feb 23 00:00:00 EST 2023
Anti-glycation and anti-inflammatory activities of anthocyanins from purple vegetables.
Food & function
Gao Q,Ma R,Shi L,Wang S,Liang Y,Zhang Z
Tue Feb 21 00:00:00 EST 2023
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Cell proliferation
Xia C,Wang G,Chen L,Geng H,Yao J,Bai Z,Deng L
Wed Mar 01 00:00:00 EST 2023
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Ye Z,Xian W,Ling GU,Zihang LI,Jingtian Z,Wenkai W,Liang Z,Mei X
Thu Jun 01 00:00:00 EDT 2023
Bacillus Calmette-Guérin-induced interleukin-10 inhibits S100A8/A9 production and hinders development of T helper type 1 memory in mice.
European journal of immunology
Wang Y,Sun Y,Zheng Y,Yang Y,He L,Qu P,Zhou F,Xu X,Bai X,Chen X,Yuan Y,Liu M,Pan Q
Sat Apr 01 00:00:00 EDT 2023
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Environmental toxicology
Li L,Jin RJ,Ji L
Wed May 10 00:00:00 EDT 2023
Evaluation of Brown Micro-Algae Synergies With Low Dose γ-Radiation Against Chronic Hepatitis Induced by D-Galactosamine in Rats.
Dose-response : a publication of International Hormesis Society
Elsaman S,Elsonbaty SM,Moawed FSM,Hegazy MGA
Fri Apr 21 00:00:00 EDT 2023
Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome†.
Biology of reproduction
Liu S,Yao Q,Li X,Wu H,Sun C,Bai W,Kang J
Tue Apr 11 00:00:00 EDT 2023
CD166-specific CAR-T cells potently target colorectal cancer cells.
Translational oncology
He S,Li S,Guo J,Zeng X,Liang D,Zhu Y,Li Y,Yang D,Zhao X
Sun Jan 01 00:00:00 EST 2023
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Chinese journal of natural medicines
Teng L,Shen Y,Qu Y,Yang L,Yang Y,Jian X,Fan S,Zhang L,Fu Q
Wed Feb 01 00:00:00 EST 2023
Alpha-kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway.
Biological research
Cui X,Li Y,Yuan S,Huang Y,Chen X,Han Y,Liu Z,Li Z,Xiao Y,Wang Y,Sun L,Liu H,Zhu X
Thu Feb 02 00:00:00 EST 2023
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Molecular and cellular probes
Pang H,Lei D,Huang J,Guo Y,Fan C
Wed Feb 01 00:00:00 EST 2023
PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats.
Journal of pharmaceutical analysis
Zhao Y,Wang Y,Wu Y,Tao C,Xu R,Chen Y,Qian L,Xu T,Lian X
Wed Feb 01 00:00:00 EST 2023
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Cellular & molecular biology letters
Adzraku SY,Wang G,Cao C,Bao Y,Wang Y,Smith AO,Du Y,Wang H,Li Y,Xu K,Qiao J,Ju W,Zeng L
Mon Jan 16 00:00:00 EST 2023
BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer.
Cell death and differentiation
Sun G,Wei Y,Zhou B,Wang M,Luan R,Bai Y,Li H,Wang S,Zheng D,Wang C,Wang S,Zeng K,Liu S,Lin L,He M,Zhang Q,Zhao Y
Mon May 01 00:00:00 EDT 2023
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
International journal of biological macromolecules
Liu X,Li H,Wang T,Yang T,Yang X,Guo K,Hu L,Ming J
Sat Jul 15 00:00:00 EDT 2023
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Cellular signalling
Wu Y,Jiang Y,Guo JQ,Yang ZW,Carvalho A,Qian LL,Ji JJ,Ji ZJ,Ma GS,Yao YY
Thu Jun 01 00:00:00 EDT 2023
Remote Ischemic Conditioning Relieves Necrotizing Enterocolitis Through Regulation of Redox and Inflammation.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhang Y,Liu Q,Gao K,Tian B,Zhu H,Liu J,Hu Y,Ye C,Guo C
Mon May 01 00:00:00 EDT 2023
Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells.
Journal of nanobiotechnology
Yu H,Teng Y,Ge J,Yang M,Xie H,Wu T,Yan Q,Jia M,Zhu Q,Shen Y,Zhang L,Zou J
Tue Mar 21 00:00:00 EDT 2023
Possible mechanisms associated with immune escape and apoptosis on anti-hepatocellular carcinoma effect of Mu Ji Fang granules.
World journal of gastrointestinal oncology
Zhang YB,Bao YR,Wang S,Li TJ,Tai H,Leng JP,Yang XX,Wang BC,Meng XS
Wed Mar 15 00:00:00 EDT 2023
DDX3X Is Hijacked by Snakehead Vesiculovirus Phosphoprotein To Facilitate Virus Replication via Stabilization of the Phosphoprotein.
Journal of virology
Bei C,Zhang C,Wu H,Feng H,Zhang YA,Tu J
Tue Feb 28 00:00:00 EST 2023
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang C,Lu T,Liu M,Yuan X,Li D,Zhang J,Zhou L,Xu M
Wed Mar 01 00:00:00 EST 2023
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Food & function
Zhao S,Hu S,Sun K,Luo L,Zeng L
Mon Mar 06 00:00:00 EST 2023
Curcumin Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Neutrophil Extracellular Traps Formation.
Journal of investigative surgery : the official journal of the Academy of Surgical Research
Zhu C,Shi S,Jiang P,Huang X,Zhao J,Jin Y,Shen Y,Zhou X,Liu H,Cai J
Fri Dec 01 00:00:00 EST 2023
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
International journal of molecular sciences
Li H,Jing Y,Qu X,Yang J,Pan P,Liu X,Gao H,Pei X,Zhang C,Yang Y
Wed Feb 01 00:00:00 EST 2023
S-Doped carbonized polymer dots inhibit early myocardial fibrosis by regulating mitochondrial function.
Biomaterials science
Wang Y,Yang M,Zhang J,Ren J,Liu N,Liu B,Lu L,Yang B
Tue Jan 31 00:00:00 EST 2023
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Biogerontology
Zhang Y,Peng X,Xue M,Liu J,Shang G,Jiang M,Chen D,Liu B,Wang Y,Jia X,Xu J,Zhang F,Hu Y
Sun Oct 01 00:00:00 EDT 2023
LINC00346 regulates NLRP1-mediated pyroptosis and autophagy via binding to microRNA-637 in vascular endothelium injury.
Cellular signalling
Ge JY,Yan XJ,Yang J,Jin H,Sun ZK,Guo JL,Zhu Y,Wang FF
Fri Sep 01 00:00:00 EDT 2023
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Ecotoxicology and environmental safety
Guo C,Lyu Y,Xia S,Ren X,Li Z,Tian F,Zheng J
Sun Jan 01 00:00:00 EST 2023
Dietary alpha-ketoglutarate enhances intestinal immunity by Th17/Treg immune response in piglets after lipopolysaccharide challenge.
Journal of animal science
Liu GM,Lu JJ,Sun WX,Jia G,Zhao H,Chen XL,Tian G,Cai JY,Zhang RN,Wang J
Tue Jan 03 00:00:00 EST 2023
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
Journal of the American Chemical Society
Morihiro K,Osumi H,Morita S,Hattori T,Baba M,Harada N,Ohashi R,Okamoto A
Wed Jan 11 00:00:00 EST 2023
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen C,Sun S,Zhao J,Wu Q,He W,Sun W
Sun Jan 01 00:00:00 EST 2023
Transcriptomic and functional analyses reveal the molecular mechanisms underlying Fe-mediated tobacco resistance to potato virus Y infection.
Frontiers in plant science
Xu C,Guo H,Li R,Lan X,Zhang Y,Xie Q,Zhu D,Mu Q,Wang Z,An M,Xia Z,Wu Y
Tue Apr 18 00:00:00 EDT 2023
CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.
Biochemical pharmacology
Mo X,Shen X,Mo X,Yu F,Tan W,Deng Z,He J,Luo Z,Chen Z,Yang J
Wed Mar 01 00:00:00 EST 2023
Neuroprotective effect of a Keap1-Nrf2 Protein-Protein Inter-action inhibitor on cerebral Ischemia/Reperfusion injury.
Bioorganic chemistry
Qi Z,Tong Y,Luo H,Chen M,Zhou N,Chen L
Wed Mar 01 00:00:00 EST 2023
Hsa_circ_0003596 enhances the development of cell renal clear cell carcinoma through the miR-502-5p/IGF1/PI3K/AKT axis.
The journal of gene medicine
Fang K,Liang S,Liu D,Yi Q,Li Y,Zhu R
Fri Dec 01 00:00:00 EST 2023
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Journal of ethnopharmacology
Li XC,Wang S,Yang XX,Li TJ,Gu JX,Zhao L,Bao YR,Meng XS
Mon Jun 12 00:00:00 EDT 2023
CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer.
Asian journal of andrology
Wang YZ,Qian YC,Yang WJ,Ye LH,Guo GD,Lv W,Huan MX,Feng XY,Wang K,Yang Z,Gao Y,Li L,Chen YL
Tue Mar 07 00:00:00 EST 2023
Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage via the FOXO3a-KEAP1-NRF2 pathway.
European journal of pharmacology
Wu J,Wang S,Zhao W,Li M,Li S
Sun Feb 05 00:00:00 EST 2023
Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway.
Ecotoxicology and environmental safety
Xu J,Wang XL,Zeng HF,Han ZY
Mon May 01 00:00:00 EDT 2023
Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway.
Cell death & disease
Lan T,Li Y,Wang Y,Wang ZC,Mu CY,Tao AB,Gong JL,Zhou Y,Xu H,Li SB,Gu B,Ma P,Luo L
Thu Jan 19 00:00:00 EST 2023
Sufentanil combined with parecoxib sodium inhibits proliferation and metastasis of HER2-positive breast cancer cells and regulates epithelial-mesenchymal transition.
Clinical & experimental metastasis
Xu S,Li X,Li W,Ma N,Ma H,Cui J,You X,Chen X
Sat Apr 01 00:00:00 EDT 2023
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Ecotoxicology and environmental safety
Liu X,Xi H,Han S,Zhang H,Hu J
Wed Mar 01 00:00:00 EST 2023
The role of 14-3-3 in the progression of vascular inflammation induced by lipopolysaccharide.
International immunopharmacology
Tan H,Li J,Jia C,Huang H,Li L,Liao B,Long Y,Nie Y,Yu F
Thu Jun 01 00:00:00 EDT 2023
A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
Journal of ethnopharmacology
Lin F,Zhang G,Yang X,Wang M,Wang R,Wan M,Wang J,Wu B,Yan T,Jia Y
Wed Mar 01 00:00:00 EST 2023
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Veterinary research
Feng L,Luo G,Li Y,Zhang C,Liu Y,Liu Y,Chen H,He D,Zhu Y,Gan L
Tue Mar 14 00:00:00 EDT 2023
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Cell death and differentiation
Chen G,Tang Q,Yu S,Shen Y,Sun J,Peng J,Yin Y,Feng G,Lu X,Mei G,Zhang Y,Wan Q,Zhang L,Chen L
Thu Jun 01 00:00:00 EDT 2023
Mitophagy associated self-degradation of phosphorylated MAP4 guarantees the migration and proliferation responses of keratinocytes to hypoxia.
Cell death discovery
Feng Y,Li L,Zhang Q,He Y,Huang Y,Zhang J,Zhang D,Huang Y,Lei X,Hu J,Luo G
Wed May 17 00:00:00 EDT 2023
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Frontiers in pharmacology
Liu X,Peng X,Cen S,Yang C,Ma Z,Shi X
Tue Mar 14 00:00:00 EDT 2023
ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis.
Biology direct
Wang T,Li T,Niu X,Hu L,Cheng J,Guo D,Ren H,Zhao R,Ji Z,Liu P,Li Y,Guo Y
Mon Feb 27 00:00:00 EST 2023
Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β.
European journal of medicinal chemistry
Xie Y,Chen C,Lin S,Yu X,Ye S,Chen X,Ouyang N,Xiong W,Li C,Xu C,Song G,Wu H
Wed Feb 15 00:00:00 EST 2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
Brain research
Liu M,Cao W,Qin X,Tong J,Wu X,Cheng Y
Wed Feb 15 00:00:00 EST 2023
Neuroprotective effect of histamine H3 receptor blockade on methamphetamine-induced cognitive impairment in mice.
Pharmacology, biochemistry, and behavior
Luo H,Li X,Fan R,Ruan Y,Qian L,Shen Y,Si Z,Li L,Liu Y
Sun Jan 01 00:00:00 EST 2023
Daucosterol Alleviates Alcohol-Induced Hepatic Injury and Inflammation through P38/NF-κB/NLRP3 Inflammasome Pathway.
Nutrients
Zhang F,Wang M,Zha Y,Zhou J,Han J,Zhang S
Sun Jan 01 00:00:00 EST 2023
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells.
Tissue engineering and regenerative medicine
Zhang Y,Wang P,Jin MX,Zhou YQ,Ye L,Zhu XJ,Li HF,Zhou M,Li Y,Li S,Liang KY,Wang Y,Gao Y,Pan MX,Zhou SQ,Peng Q
Thu Jun 01 00:00:00 EDT 2023
A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/JAK2/STAT3 signaling pathway in lung adenocarcinoma.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Liang Q,Gong M,Zou JH,Luo MY,Jiang LL,Wang C,Shen NX,Zhang MC,Xu L,Lei HM,Zhang KR,Zhang R,Zhuang G,Zhu L,Chen HZ,Zhou L,Shen Y
Mon May 01 00:00:00 EDT 2023
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Molecular neurobiology
Chen Y,Huang J,Liu J,Zhu H,Li X,Wen J,Tian M,Ren J,Zhou L,Yang Q
Tue Aug 01 00:00:00 EDT 2023
NFYAv1 is a Tumor-Promoting Transcript Associated with Poor Prognosis of Hepatocellular Carcinoma.
Medical science monitor : international medical journal of experimental and clinical research
Li Z,You C,Huang J,Zhang M
Sat Jan 21 00:00:00 EST 2023
Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env+ cells invivo.
Virologica Sinica
Pan H,Yang X,Wang J,Liang H,Jiang Z,Zhao L,Wang Y,Liang Z,Shen X,Lin Q,Liang Y,Yang J,Lu P,Zhu Y,Li M,Wang P,Xu J,Lu H,Zhu H
Sat Apr 01 00:00:00 EDT 2023
Expression of group II metabotropic glutamate receptors in rat superior cervical ganglion.
Autonomic neuroscience : basic & clinical
Wei X,Zhao C,Jia X,Zhao B,Liu Y
Sun Jan 01 00:00:00 EST 2023
LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.
Journal of ovarian research
Dey G,Bharti R,Braley C,Alluri R,Esakov E,Crean-Tate K,McCrae K,Joehlin-Price A,Rose PG,Lathia J,Gong Z,Reizes O
Tue Jun 27 00:00:00 EDT 2023
Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus.
Neuroscience bulletin
Yan Y,Zhu M,Cao X,Xu G,Shen W,Li F,Zhang J,Luo L,Zhang X,Zhang D,Liu T
Mon May 01 00:00:00 EDT 2023
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Stem cells and development
Li T,Tang Q,Xu J,Ye X,Chen K,Zhong J,Zhu J,Lu S,Zhu T
Fri Sep 01 00:00:00 EDT 2023
S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling.
Molecular medicine reports
Bai Y,Guo N,Xu Z,Chen Y,Zhang W,Chen Q,Bi Z
Wed Feb 01 00:00:00 EST 2023
ANXA10 is a prognostic biomarker and suppressor of hepatocellular carcinoma: a bioinformatics analysis and experimental validation.
Scientific reports
Zhang C,Peng L,Gu H,Wang J,Wang Y,Xu Z
Sat Jan 28 00:00:00 EST 2023
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology
Dong C,Song C,He Z,Song Q,Song T,Liu J,Xiong Y,Su X,Zhou J,Yang S,Liao W
Sat Apr 01 00:00:00 EDT 2023
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
Journal of ethnopharmacology
Niu C,Hu XL,Yuan ZW,Xiao Y,Ji P,Wei YM,Hua YL
Tue Jan 10 00:00:00 EST 2023
Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress.
Scientific reports
Pei Z,Ji J,Gao Y,Wang H,Wu Y,Yang J,Yang Q,Zhang L
Mon Jun 05 00:00:00 EDT 2023
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
Cancer research
Zhao M,Li Y,Lu C,Ding F,Xu M,Ge X,Li M,Wang Z,Yin J,Zhang J,Wang X,Ge Z,Xiao H,Xiao Y,Liu H,Liu W,Cao Y,Wang Q,You Y,Wang X,Yang K,Shi Z,Qian X
Tue Apr 04 00:00:00 EDT 2023
Decreased AGGF1 facilitates the progression of placenta accreta spectrum via mediating the P53 signaling pathway under the regulation of miR-1296-5p.
Reproductive biology
Wang R,Zhao J,Liu C,Li S,Liu W,Cao Q
Wed Mar 01 00:00:00 EST 2023
Preventive effect of salmon sperm DNA on acute carbon tetrachloride-induced liver injury in mice through Nrf2/ARE and mitochondrial apoptosis pathway.
Food science & nutrition
Huang X,Chu X,Tian Y,Xue Y,Zhang L,Li J,Hou H,Dong P,Wang J
Wed Feb 01 00:00:00 EST 2023
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Annals of translational medicine
Zhang N,Wang F,Zhu L,Chang R,Mok SRS,Peixoto RD,Tang W,Chen Z
Sun Jan 15 00:00:00 EST 2023
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia.
Cell death & disease
Guo Q,Fan Y,Wang Q,Li B,Qiu W,Qi Y,Pan Z,Zhang S,Zhao S,Yang K,Xu H,Li M,Gao Z,Xu J,Wang H,Wang S,Tang Q,Qiu J,Guo X,Deng L,Zhang P,Zhao R,Xue H,Wang C,Li G
Tue Feb 21 00:00:00 EST 2023
Activation of PPARγ prevents ferroptosis-induced damage through Nrf2/Gpx4 signaling pathway in rat hippocampus following epilepsy.
Neuroreport
Wang MJ,Liu X,Chi S,Wang FY,Zhang L,Yao MY,Liu T,Gao J
Wed Apr 05 00:00:00 EDT 2023
Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition.
BMC cancer
Amos A,Jiang N,Zong D,Gu J,Zhou J,Yin L,He X,Xu Y,Wu L
Fri Feb 03 00:00:00 EST 2023
Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Facilitates Injured Endometrial Restoring in Early Repair Period through miR-202-3p Mediating Formation of ECM.
Stem cell reviews and reports
Wang S,Liu T,Nan N,Lu C,Liang M,Wang S,Wang H,He B,Chen X,Xu X,Zheng Y
Tue Aug 01 00:00:00 EDT 2023
Adjuvant therapy with Huatan Sanjie Granules improves the prognosis of patients with primary liver cancer: a cohort study and the investigation of its mechanism of action based on network pharmacology.
Frontiers in pharmacology
Yuan J,Abdurahman A,Cui N,Hao T,Zou J,Liu L,Wu Y
Mon Jun 19 00:00:00 EDT 2023
Decreasing GDF15 Promotes Inflammatory Signals and Neutrophil Infiltration in Psoriasis Models.
The Journal of investigative dermatology
Zhang J,He L,Wang Z,Shao S,Qiao P,Zhang J,Zhang K,Li C,Zhang Y,Wang G,Li M
Wed Mar 01 00:00:00 EST 2023
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
iScience
Wu H,Wu Z,Qiu Y,Zhao F,Liao M,Zhong Z,Chen J,Zeng Y,Liu R
Fri Jun 16 00:00:00 EDT 2023
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Biomedicines
Zhang Y,Fu J,Han Y,Feng D,Yue S,Zhou Y,Luo Z
Wed Apr 26 00:00:00 EDT 2023
MC1R Peptide Agonist Self-Assembles into a Hydrogel That Promotes Skin Pigmentation for Treating Vitiligo.
ACS nano
Zhu C,Li T,Wang Z,Li Z,Wei J,Han H,Yuan D,Cai M,Shi J
Tue May 09 00:00:00 EDT 2023
VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation.
Research square
Shin Y,Kim S,Liang G,Ulmer TS,An W
Wed Jul 12 00:00:00 EDT 2023
Polystyrene Microplastics Induce Oxidative Stress in Mouse Hepatocytes in Relation to Their Size.
International journal of molecular sciences
Zou H,Qu H,Bian Y,Sun J,Wang T,Ma Y,Yuan Y,Gu J,Bian J,Liu Z
Mon Apr 17 00:00:00 EDT 2023
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Naunyn-Schmiedeberg's archives of pharmacology
Wei Y,Sun L,Liu C,Li L
Thu Jun 01 00:00:00 EDT 2023
Glycoside combinations of Buyang Huanwu decoction ameliorate atherosclerosis via STAT3, HIF-1, and VEGF.
Naunyn-Schmiedeberg's archives of pharmacology
Yan F,Ding H,Sun Z,Liu J,Li J,Zhou D,Zhang W
Thu Jun 01 00:00:00 EDT 2023
Scutellarin Alleviates Ischemic Brain Injury in the Acute Phase by Affecting the Activity of Neurotransmitters in Neurons.
Molecules (Basel, Switzerland)
Wang C,Liu Y,Liu X,Zhang Y,Yan X,Deng X,Shi J
Tue Apr 04 00:00:00 EDT 2023
Huntingtin-associated protein 1 is a potential tumor suppressor for gastric cancer.
Molecular biology reports
Qu YM,Chen A,Zhao X,Wang Z,Guo D,Shao SL,Tao YY,Li QJ,Wang MY,Ma WS
Wed Feb 01 00:00:00 EST 2023
Epitranscriptic regulation of HRAS by N6-methyladenosine drives tumor progression.
Proceedings of the National Academy of Sciences of the United States of America
Pan Y,Gu Y,Liu T,Zhang Q,Yang F,Duan L,Cheng S,Zhu X,Xi Y,Chang X,Ye Q,Gao S
Tue Apr 04 00:00:00 EDT 2023
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4.
Reproductive sciences (Thousand Oaks, Calif.)
Liu W,Cheng L,Du Y,Liu X,Ma J,Yan L
Sun Oct 01 00:00:00 EDT 2023
Metabolic genes, a potential predictor of prognosis and immunogenicity of clear cell renal cell carcinoma.
American journal of cancer research
Ji CJ,Wei XY,Yao LY,Wang YC,Cong R,Song NH
Sun May 14 00:00:00 EDT 2023
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Animals : an open access journal from MDPI
Li Y,Zhang G,Wen F,Xian M,Guo S,Zhang X,Feng X,Hu Z,Hu J
Sun Apr 23 00:00:00 EDT 2023
Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.
Molecular biology reports
Zou X,Liu C,Huang Z,Xiang S,Li K,Yuan Y,Hao Y,Zhou F
Sat Jul 01 00:00:00 EDT 2023
SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway.
iScience
Wang D,Li Y,Xu C,Wang H,Huang X,Jin X,Ren S,Gao J,Tong J,Liu J,Zhou J,Shi L
Fri Jun 16 00:00:00 EDT 2023
Acupuncture regulates the apoptosis of ovarian granulosa cells in polycystic ovarian syndrome-related abnormal follicular development through LncMEG3-mediated inhibition of miR-21-3p.
Biological research
Chen X,He H,Long B,Wei B,Yang P,Huang X,Wang Q,Lin J,Tang H
Mon Jun 12 00:00:00 EDT 2023
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Frontiers in bioengineering and biotechnology
Zhu Y,Wang T,Bao MJ,Qu XH,Li ZM
Tue May 23 00:00:00 EDT 2023
Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis.
Food & function
Yang Q,He Y,Tian L,Zhang Z,Qiu L,Tao X,Wei H
Tue Feb 21 00:00:00 EST 2023
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Chemico-biological interactions
Qian X,Zhu L,Xu M,Liu H,Yu X,Shao Q,Qin J
Fri Sep 01 00:00:00 EDT 2023
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
Biochemical and biophysical research communications
Zhu Q,Luo Y,Wen Y,Wang D,Li J,Fan Z
Sun Mar 05 00:00:00 EST 2023
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Clinical and experimental pharmacology & physiology
Wu H,Wu L,Xiao L,Gu Y,Liu H,Zhang L,Zhang M,Qi L
Sat Apr 01 00:00:00 EDT 2023
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Experimental cell research
He W,Tong G,Fan H,Zhen C,Zeng L,Xue L,Chen J,Sun Z,He P
Wed Feb 15 00:00:00 EST 2023
Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody.
Developmental dynamics : an official publication of the American Association of Anatomists
Rovira M,Miserocchi M,Montanari A,Hammou L,Chomette L,Pozo J,Imbault V,Bisteau X,Wittamer V
Wed Mar 01 00:00:00 EST 2023
NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling.
BMC cancer
Ma S,Chen Y,Quan P,Zhang J,Han S,Wang G,Qi R,Zhang X,Wang F,Yuan J,Yang X,Jia W,Qin W
Tue Mar 28 00:00:00 EDT 2023
Silencing of OGDHL promotes liver cancer metastasis by enhancing hypoxia inducible factor 1 α protein stability.
Cancer science
Dai W,Li Y,Sun W,Ji M,Bao R,Chen J,Xu S,Dai Y,Chen Y,Liu W,Ge C,Sun W,Mo W,Guo C,Xu X
Sat Apr 01 00:00:00 EDT 2023
Afatinib combined with anti-PD1 enhances immunotherapy of hepatocellular carcinoma via ERBB2/STAT3/PD-L1 signaling.
Frontiers in oncology
Yu C,Zhang X,Wang M,Xu G,Zhao S,Feng Y,Pan C,Yang W,Zhou J,Shang L,Ma Y
Mon Jun 19 00:00:00 EDT 2023
P4HA1 activates HMGCS1 to promote nasopharyngeal carcinoma ferroptosis resistance and progression.
Cellular signalling
Zhou R,Qiu L,Zhou L,Geng R,Yang S,Wu J
Mon May 01 00:00:00 EDT 2023
Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway.
Journal of inflammation research
Ma J,Han Z,Jiao R,Yuan G,Ma C,Yan X,Meng A
Tue Mar 21 00:00:00 EDT 2023
Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu H,Yan S,Jin M,Wei Y,Zhao L,Cheng J,Ding L,Feng H
Mon May 01 00:00:00 EDT 2023
Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone-derived IGF-1 secretion.
Cell proliferation
Yang Y,Yuan K,Liu Y,Wang Q,Lin Y,Yang S,Huang K,Kan T,Zhang Y,Xu M,Yu Z,Fan Q,Wang Y,Li H,Tang T
Sun Oct 01 00:00:00 EDT 2023
Construction and Rescue of a DNA-Launched DENV2 Infectious Clone.
Viruses
Holliday M,Corliss L,Lennemann NJ
Wed Jan 18 00:00:00 EST 2023
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
Bioorganic chemistry
Zhang RL,Lei BX,Wu GY,Wang YY,Huang QH
Sat Apr 01 00:00:00 EDT 2023
The histone H2B ubiquitination regulator Wac is essential for plasma cell differentiation.
FEBS letters
Li Y,Ruan GX,Chen W,Huang H,Zhang R,Wang J,Ouyang Y,Zhu Z,Meng L,Wang R,Huo J,Xu S,Ou X
Sat Jul 01 00:00:00 EDT 2023
Nervonic acid improves liver inflammation in a mouse model of Parkinson's disease by inhibiting proinflammatory signaling pathways and regulating metabolic pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang X,Liang T,Mao Y,Li Z,Li X,Zhu X,Cao F,Zhang J
Tue Aug 01 00:00:00 EDT 2023
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Nature cell biology
Ji Y,Luo Y,Wu Y,Sun Y,Zhao L,Xue Z,Sun M,Wei X,He Z,Wu SA,Lin LL,Lu Y,Chang L,Chen F,Chen S,Qian W,Xu X,Chen S,Pan D,Zhou Z,Xia S,Hu CA,Liang T,Qi L
Mon May 01 00:00:00 EDT 2023
Preoperative Pain Facilitates Postoperative Cognitive Dysfunction via Periaqueductal Gray Matter-Dorsal Raphe Circuit.
Neuroscience
Deng H,Wu Y,Gao P,Kong D,Pan C,Xu S,Tang D,Jiao Y,Wen D,Yu W
Tue Aug 01 00:00:00 EDT 2023
SATB1 regulates 3D genome architecture in T cells by constraining chromatin interactions surrounding CTCF-binding sites.
Cell reports
Wang B,Ji L,Bian Q
Tue Apr 25 00:00:00 EDT 2023
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis.
Pathology, research and practice
Sun W,Lei X,Lu Q,Wu Q,Ma Q,Huang D,Zhang Y
Wed Mar 01 00:00:00 EST 2023
The mechanism of monobutyl phthalate -induced ferroptosis via TNF/IL6/STAT3 signal pathway in TM-3 cells.
The Journal of toxicological sciences
Guo X,Hao Y,Ma H,Li H,Li L,Yan F,Huang J,Li L
Tue May 02 00:00:00 EDT 2023
BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
Journal of assisted reproduction and genetics
Liu F,Li M
Wed Mar 01 00:00:00 EST 2023
Targeting hexokinase 1 alleviates NLRP3-mediated inflammation in apical periodontitis: A laboratory investigation.
International endodontic journal
Qian Y,Chen D,Zhu Y,Wu J,Wang Y,Yang W
Thu Jun 01 00:00:00 EDT 2023
Irisin attenuates fine particulate matter induced acute lung injury by regulating Nod2/NF-κB signaling pathway.
Immunobiology
Jiao R,Han Z,Ma J,Wu S,Wang Z,Zhou G,Liu X,Li J,Yan X,Meng A
Mon May 01 00:00:00 EDT 2023
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Neurochemical research
Huang Y,Liu Z,Wang X,Li Y,Liu L,Li B
Fri Sep 01 00:00:00 EDT 2023
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Inflammopharmacology
Xia J,Li J,Deng M,Yin F,Liu J,Wang J
Tue Aug 01 00:00:00 EDT 2023
Ring domains are essential for GATOR2-dependent mTORC1 activation.
Molecular cell
Jiang C,Dai X,He S,Zhou H,Fang L,Guo J,Liu S,Zhang T,Pan W,Yu H,Fu T,Li D,Inuzuka H,Wang P,Xiao J,Wei W
Thu Jan 05 00:00:00 EST 2023
Protective effects of pentoxifylline against chlorine-induced acute lung injury in rats.
BMC pharmacology & toxicology
Liu MM,Liu JZ,Zhao CQ,Guo P,Wang Z,Wu H,Yu W,Liu R,Hai CX,Zhang XD
Mon Feb 27 00:00:00 EST 2023
The RNA-binding protein hnRNP F is required for the germinal center B cell response.
Nature communications
Huang H,Li Y,Zhang G,Ruan GX,Zhu Z,Chen W,Zou J,Zhang R,Wang J,Ouyang Y,Xu S,Ou X
Thu Mar 30 00:00:00 EDT 2023
Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.
Experimental cell research
Qiu R,Zhao S,Lu C,Xu Z,Shu E,Weng Q,Chen W,Fang S,Chen W,Zheng L,Zhao Z,Yang Y,Ji J
Sat Apr 01 00:00:00 EDT 2023
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Journal of translational medicine
Zhang M,Hong X,Ma N,Wei Z,Ci X,Zhang S
Tue Jul 04 00:00:00 EDT 2023
TREM2 Inhibits Tau Hyperphosphorylation and Neuronal Apoptosis via the PI3K/Akt/GSK-3β Signaling Pathway In vivo and In vitro.
Molecular neurobiology
Peng X,Guo H,Zhang X,Yang Z,Ruganzu JB,Yang Z,Wu X,Bi W,Ji S,Yang W
Mon May 01 00:00:00 EDT 2023
Mesenchymal stem cell-derived extracellular vesicles carrying miR-99b-3p restrain microglial activation and neuropathic pain by stimulating autophagy.
International immunopharmacology
Gao X,Gao LF,Kong XQ,Zhang YN,Jia S,Meng CY
Wed Feb 01 00:00:00 EST 2023
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang J,Zhang L,Wang T,Zhang J,Li M,Jin X,Tan X,Wang G,Zhao F,Jin Y
Thu Jun 01 00:00:00 EDT 2023
Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis.
Cell death & disease
Liu H,Yin H,Wang Z,Yuan Q,Xu F,Chen Y,Li C
Sat Feb 11 00:00:00 EST 2023
Supplemental Clostridium butyricum modulates lipid metabolism by reshaping the gut microbiota composition and bile acid profile in IUGR suckling piglets.
Journal of animal science and biotechnology
Zhang X,Yun Y,Lai Z,Ji S,Yu G,Xie Z,Zhang H,Zhong X,Wang T,Zhang L
Mon Mar 13 00:00:00 EDT 2023
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Molecular and cellular biochemistry
Gao J,Zhou J,Zhang M,Zhang Y,Zeng Y,Li S,Xu K,Yao R
Fri May 19 00:00:00 EDT 2023
Mitochondria-Targeted Nanosystem Enhances Radio-Radiodynamic-Chemodynamic Therapy on Triple Negative Breast Cancer.
ACS applied materials & interfaces
Li J,You Z,Zhai S,Zhao J,Lu K
Wed May 10 00:00:00 EDT 2023
Sphingosine-1-Phosphate Receptor 4 Attenuates Neutrophilic Airway Inflammation in Experimental Asthma via Repressing Proinflammatory Macrophage Activation.
International journal of biological sciences
Wang S,Tian Z,Lu Y,Huang Z,Fan Y,Li B,Zheng H,Wu X,Wang M,Zhao J,Xie J
Mon Apr 17 00:00:00 EDT 2023
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Journal of gastrointestinal oncology
Yang H,Pu L,Li R,Zhu R
Sat Apr 29 00:00:00 EDT 2023
Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice.
Neural plasticity
Wei W,Lin Z,Xu P,Lv X,Lin L,Li Y,Zhou Y,Lu T,Xue X
Mon Apr 03 00:00:00 EDT 2023
Danlou tablet inhibits high-glucose-induced cardiomyocyte apoptosis via the miR-34a-SIRT1 axis.
Heliyon
Chen R,Chen H,Yang Z,Zhu L,Bei Y,Chen W,Qiu Y
Wed Mar 01 00:00:00 EST 2023
Knockdown of Brg1 reduced mucus secretion in HDM stimulated airway inflammation.
Molecular immunology
Xu M,Hu J,Yang L,Gen G,Fu Z,Luo Z,Zou W
Sun Jan 01 00:00:00 EST 2023
Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway.
Asian journal of andrology
Liang HY,Peng F,Pan MJ,Liao SL,Wei C,Wei GY,Xie X,Xue KY,Chen MK,Yang JK,Guo WB,Liu CD,Zhou QZ
Fri Jul 21 00:00:00 EDT 2023
The antiviral activity of tripartite motif protein 38 in hepatitis B virus replication and gene expression and its association with treatment responses during PEG-IFN-α antiviral therapy.
Virology
Luo H,Hu X,Li Y,Lei D,Tan G,Zeng Y,Qin B
Wed Feb 01 00:00:00 EST 2023
Fluvoxamine alleviates bleomycin-induced lung fibrosis via regulating the cGAS-STING pathway.
Pharmacological research
Xie X,Wu X,Zhao D,Liu Y,Du Q,Li Y,Xu Y,Li Y,Qiu Y,Yang Y
Sun Jan 01 00:00:00 EST 2023
Macrophage migration inhibitory factor facilitates astrocytic production of the CCL2 chemokine following spinal cord injury.
Neural regeneration research
Zhang H,Hu YM,Wang YJ,Zhou Y,Zhu ZJ,Chen MH,Wang YJ,Xu H,Wang YH
Tue Aug 01 00:00:00 EDT 2023
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Analytical cellular pathology (Amsterdam)
Liu PL,Diao JY,Wang Q,Liu H,Zhang Y,Liang JQ,Zhang F,Liang XJ,Zhao HM
Fri May 19 00:00:00 EDT 2023
Transcytosable Peptide-Paclitaxel Prodrug Nanoparticle for Targeted Treatment of Triple-Negative Breast Cancer.
International journal of molecular sciences
Wang L,Zhao C,Lu L,Jiang H,Wang F,Zhang X
Tue Feb 28 00:00:00 EST 2023
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Microbiology spectrum
Wu Y,Dong Z,Jiang X,Qu L,Zhou W,Sun X,Hou J,Xu H,Cheng M
Thu Jun 15 00:00:00 EDT 2023
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway.
European journal of pharmacology
Chen S,Sun S,Feng Y,Li X,Yin G,Liang P,Yu W,Meng D,Zhang X,Liu H,Zhang F
Sat Aug 05 00:00:00 EDT 2023
Comprehensive analysis of lncRNA-mRNA co-expression networks in HPV-driven cervical cancer reveals the pivotal function of LINC00511-PGK1 in tumorigenesis.
Computers in biology and medicine
Xin X,Jia-Yin Y,Jun-Yang H,Rui W,Xiong-Ri K,Long-Rui D,Liu J,Jue-Yu Z
Thu Jun 01 00:00:00 EDT 2023
Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT.
Cancer gene therapy
Zheng Y,Jia H,Wang P,Liu L,Chen Z,Xing X,Wang J,Tan X,Wang C
Sun Jan 01 00:00:00 EST 2023
Anti-Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics-integrated experimental study.
Phytotherapy research : PTR
Li H,Wang C,Jin Y,Cai Y,Yao J,Meng Q,Wu J,Wang H,Sun H,Liu M
Sun Jan 01 00:00:00 EST 2023
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Phytotherapy research : PTR
Gu L,Wang F,Wang Y,Sun D,Sun Y,Tian T,Meng Q,Yin L,Xu L,Lu X,Peng J,Lin Y,Sun P
Tue Aug 01 00:00:00 EDT 2023
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Biochemical and biophysical research communications
Fan J,Liu M,Li X,Gao S,Wang Y,Li A,Chen L,Zhou D,Chen H,Xu Z,Wu Z,Wu K
Sun Apr 02 00:00:00 EDT 2023
Two Resveratrol Oligomers Inhibit Cathepsin L Activity to Suppress SARS-CoV-2 Entry.
Journal of agricultural and food chemistry
Wang C,Ye X,Ding C,Zhou M,Li W,Wang Y,You Q,Zong S,Peng Q,Duanmu D,Chen H,Sun B,Qiao J
Wed Apr 12 00:00:00 EDT 2023
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain.
Cell proliferation
Wang Y,Su L,Wang W,Zhao J,Wang Y,Li S,Liu Y,Chai R,Li X,Teng Z,Liu C,Hu B,Ji F,Jiao J
Mon May 01 00:00:00 EDT 2023
Study on the pharmacological mechanisms of sodium-glucose co-transporter 2 inhibitors in obesity-related atrial fibrillation based on network pharmacology and experimental verification.
Annals of translational medicine
Zhao Q,Wang P,Zhao M,Hong J,Zhang N,Lin K,Li Y
Fri Apr 28 00:00:00 EDT 2023
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Molecular pharmaceutics
Cheng B,Chu X,Liu R,Ma X,Wang M,Zhang J,Jiao P,Gao Q,Ma W,Zhang Y,Zhao C,Zhou D,Xiao S
Mon Jan 02 00:00:00 EST 2023
PbO nanoparticles increase the expression of ICAM-1 and VCAM-1 by increasing reactive oxygen species production in choroid plexus.
Environmental science and pollution research international
Wang W,Li S,Wang X,Wang J,Zhang Y
Wed Mar 01 00:00:00 EST 2023
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
Biochemical and biophysical research communications
Zhang X,Zhang X,Yang G,Wan L,Yin F,Li H,Yin D
Sun Aug 20 00:00:00 EDT 2023
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia.
Journal of cardiovascular translational research
Zou X,Liao Y,Liu Z,Xu X,Sun W,Qin H,Wang H,Liu J,Jing T
Wed Feb 01 00:00:00 EST 2023
Title: Bioinformatic Identification of Genes Involved in Diabetic Nephropathy Fibrosis and their Clinical Relevance.
Biochemical genetics
Bai Y,Ma L,Deng D,Tian D,Liu W,Diao Z
Tue Aug 01 00:00:00 EDT 2023
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
Molecular therapy : the journal of the American Society of Gene Therapy
Wang Y,Chen YY,Gao GB,Zheng YH,Yu NN,Ouyang L,Gao X,Li N,Wen SY,Huang S,Zhao Q,Liu L,Cao M,Zhang S,Zhang J,He QY
Wed Jul 05 00:00:00 EDT 2023
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S-glutathionylation of optic atrophy 1.
Free radical biology & medicine
Zhu H,Yan C,Yao P,Li P,Li Y,Yang H
Tue Aug 01 00:00:00 EDT 2023
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Heliyon
Wang Y,Yang X,Cao Y,Li X,Xu R,Yan J,Guo Z,Sun S,Sun X,Wu Y
Wed Mar 01 00:00:00 EST 2023
YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2.
Genome biology
Wang X,Fan W,Li N,Ma Y,Yao M,Wang G,He S,Li W,Tan J,Lu Q,Hou S
Fri Apr 21 00:00:00 EDT 2023
mTOR/ULK1 signaling axis mediated ultrashort wave regulation of autophagy to alleviate diabetic kidney disease.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Yan Y,Yu S,Fan Y
Wed Nov 01 00:00:00 EDT 2023
Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy.
Pharmaceutical biology
Ma M,Wei N,Yang J,Ding T,Song A,Chen L,Zheng S,Jin H
Fri Dec 01 00:00:00 EST 2023
Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression.
Molecular nutrition & food research
Wang G,Chen L,Qin S,Geng H,Xia C,Zheng Y,Lei X,Zhang J,Wu S,Yao J,Deng L
Wed Mar 01 00:00:00 EST 2023
Farnesoid X Receptor (FXR) Regulates mTORC1 Signaling and Autophagy by Inhibiting SESN2 Expression.
Molecular nutrition & food research
Wang G,Chen L,Qin S,Geng H,Xia C,Zheng Y,Lei X,Zhang J,Wu S,Yao J,Deng L
Wed Mar 01 00:00:00 EST 2023
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Neurochemical research
Li B,Lu Y,Wang R,Xu T,Lei X,Jin H,Gao X,Xie Y,Liu X,Zeng J
Wed Feb 01 00:00:00 EST 2023
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Experimental and therapeutic medicine
Qian X,Xiong S,Chen Q,Zhang J,Xie J
Sat Apr 01 00:00:00 EDT 2023
Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin‑1 receptor.
Oncology reports
Zheng Y,Sang M,Liu F,Gu L,Li J,Wu Y,Shan B
Sat Jul 01 00:00:00 EDT 2023
Selenium supplementation enhanced the expression of selenoproteins in hippocampus and played a neuroprotective role in LPS-induced neuroinflammation.
International journal of biological macromolecules
Liang X,Xue Z,Zheng Y,Li S,Zhou L,Cao L,Zou Y
Sat Apr 15 00:00:00 EDT 2023
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Nature communications
Xu X,Chang CW,Li M,Omabe K,Le N,Chen YH,Liang F,Liu Y
Sat Mar 04 00:00:00 EST 2023
LncRNA UCA1 promoted cisplatin resistance in lung adenocarcinoma with HO1 targets NRF2/HO1 pathway.
Journal of cancer research and clinical oncology
Shi W,Ling L,Li C,Wu R,Zhang M,Shao F,Wang Y
Wed Mar 01 00:00:00 EST 2023
Role of SESTRIN2/AMPK/ULK1 pathway activation and lysosomes dysfunction in NaAsO2-induced liver injury under oxidative stress.
Ecotoxicology and environmental safety
Bi D,Zheng D,Shi M,Hu Q,Wang H,Zhi H,Lou D,Zhang A,Hu Y
Sat Apr 01 00:00:00 EDT 2023
4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.
Molecular medicine (Cambridge, Mass.)
Xu L,Cai J,Li C,Yang M,Duan T,Zhao Q,Xi Y,Sun L,He L,Tang C,Sun L
Mon Apr 24 00:00:00 EDT 2023
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ma D,Wang Z,He Z,Wang Z,Chen Q,Qin F,Zeng M,Chen J
Sun Jan 01 00:00:00 EST 2023
Dose-Dependent Effects in Plasma Oncotherapy: Critical In Vivo Immune Responses Missed by In Vitro Studies.
Biomolecules
He Y,Gong F,Jin T,Liu Q,Fang H,Chen Y,Wang G,Chu PK,Wu Z,Ostrikov KK
Fri Apr 21 00:00:00 EDT 2023
SlMYB99-mediated auxin and abscisic acid antagonistically regulate ascorbic acids biosynthesis in tomato.
The New phytologist
Xu X,Huang B,Fang X,Zhang Q,Qi T,Gong M,Zheng X,Wu M,Jian Y,Deng J,Cheng Y,Li Z,Deng W
Tue Aug 01 00:00:00 EDT 2023
The main e-cigarette component vegetable glycerin enhances neutrophil migration and fibrosis in endotoxin-induced lung injury via p38 MAPK activation.
Respiratory research
Su VY,Chen WC,Yu WK,Wu HH,Chen H,Yang KY
Tue Jan 10 00:00:00 EST 2023
The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway.
The British journal of nutrition
Zhu X,Liu J,Cai M,Bao L,Pan Y,Wu P,Chu W,Zhang J
Mon Aug 28 00:00:00 EDT 2023
The circadian rhythm gene Bmal1 ameliorates acute deoxynivalenol-induced liver damage.
Archives of toxicology
Yang LN,Xu S,Tang M,Zhou X,Liao Y,Nüssler AK,Liu L,Yang W
Wed Mar 01 00:00:00 EST 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
1α,25(OH)2D3 Promotes the Autophagy of Porcine Ovarian Granulosa Cells as a Protective Mechanism against ROS through the BNIP3/PINK1 Pathway.
International journal of molecular sciences
Wang S,Yao Q,Zhao F,Cui W,Price CA,Wang Y,Lv J,Tang H,Jiang Z
Wed Feb 22 00:00:00 EST 2023
Sirt3-dependent regulation of mitochondrial oxidative stress and apoptosis contributes to the dysfunction of pancreatic islets after severe burns.
Free radical biology & medicine
Liu X,Xie X,Li D,Liu Z,Zhang B,Zang Y,Yuan H,Shen C
Wed Mar 01 00:00:00 EST 2023
Role of FLCN Phosphorylation in Insulin-Mediated mTORC1 Activation and Tumorigenesis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang G,Chen L,Lei X,Qin S,Geng H,Zheng Y,Xia C,Yao J,Meng T,Deng L
Thu Jun 01 00:00:00 EDT 2023
Role of FLCN Phosphorylation in Insulin-Mediated mTORC1 Activation and Tumorigenesis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang G,Chen L,Lei X,Qin S,Geng H,Zheng Y,Xia C,Yao J,Meng T,Deng L
Thu Jun 01 00:00:00 EDT 2023
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Food & function
Wei R,Su Z,Mackenzie GG
Mon Mar 20 00:00:00 EDT 2023
Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).
Cancers
Li X,Huang J,Wu Q,Du Q,Wang Y,Huang Y,Cai X,Geller DA,Yan Y
Mon Jan 30 00:00:00 EST 2023
Microcystin‑leucine arginine promotes colorectal cancer cell proliferation by activating the PI3K/Akt/Wnt/β‑catenin pathway.
Oncology reports
Tang Y,Yi X,Zhang X,Liu B,Lu Y,Pan Z,Yu T,Feng W
Sun Jan 01 00:00:00 EST 2023
PLD2 deletion alleviates disruption of tight junctions in sepsis-induced ALI by regulating PA/STAT3 phosphorylation pathway.
International immunopharmacology
Qian T,Qi B,Fei Y,Li J,Luo L,Lv B,Song Y,Sheng S,Xiao W,Huang X,Wang X
Sun Jan 01 00:00:00 EST 2023
Application of neural network-based image analysis to detect sister chromatid cohesion defects.
Scientific reports
Ikemoto D,Taniguchi T,Hirota K,Nishikawa K,Okubo K,Abe T
Mon Feb 06 00:00:00 EST 2023
An in vivo and in vitro model on the protective effect of cilnidipine on contrast-induced nephropathy via regulation of apoptosis and CaMKⅡ/mPTP pathway.
Journal of biochemical and molecular toxicology
Liu K,Hu C,Yin W,Zhou L,Gu X,Zuo X
Sun Jan 01 00:00:00 EST 2023
Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation.
International immunopharmacology
Zhang X,Huang S,Zhuang Z,Han X,Xie M,Yu S,Hua M,Liang Z,Meng C,Yin L,Zhuang X,Chen S
Mon May 01 00:00:00 EDT 2023
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Experimental cell research
Liu B,Qu X,Wang J,Xu L,Zhang L,Xu B,Su J,Bian X
Sat Apr 01 00:00:00 EDT 2023
miR-656-3p inhibits melanomas in vitro and in vivo by inducing senescence via inhibiting LMNB2.
Journal of cancer research and clinical oncology
Sun J,Lui K,Pang Q,Xu M,Zhao H,Shao J,Yu Y,Chu X,Liang Y,Xu J,Shen Z
Fri Sep 01 00:00:00 EDT 2023
DNA damage-inducible transcript 3 deficiency promotes bone resorption in murine periodontitis models.
Journal of periodontal research
Luo Y,Yang B,Dong W,Yu W,Jia M,Wang J
Tue Aug 01 00:00:00 EDT 2023
Dysfunction of inhibitory interneurons contributes to synaptic plasticity via GABABR-pNR2B signaling in a chronic migraine rat model.
Frontiers in molecular neuroscience
Zeng X,Niu Y,Qin G,Zhang D,Chen L
Mon Jun 19 00:00:00 EDT 2023
Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway.
Cell death & disease
Hao J,Chen Q,Feng Y,Jiang Q,Sun H,Deng B,Huang X,Guan J,Chen Q,Liu X,Wang Y,Cao P,Feng F,Li X
Thu Apr 06 00:00:00 EDT 2023
Autophagy ameliorates Pseudomonas aeruginosa-infected diabetic wounds by regulating the toll-like receptor 4/myeloid differentiation factor 88 pathway.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Ji X,Jin P,Yu P,Wang P
Fri May 26 00:00:00 EDT 2023
Anti-inflammatory labdane diterpenoids from the aerial parts of Leonurus japonicus.
Phytochemistry
Wei QH,Cao XX,Xu DF,Wang ST,Zhang JS,Zhang H
Thu Jun 01 00:00:00 EDT 2023
Critical role of caveolin-1 in intestinal ischemia reperfusion by inhibiting protein kinase C βII.
Free radical biology & medicine
Chen Z,Wang Z,Liu D,Zhao X,Ning S,Liu X,Wang G,Zhang F,Luo F,Yao J,Tian X
Sun Jan 01 00:00:00 EST 2023
Tartary buckwheat flavonoids alleviates high-fat diet induced kidney fibrosis in mice by inhibiting MAPK and TGF-β1/Smad signaling pathway.
Chemico-biological interactions
Liu S,Fu S,Jin Y,Geng R,Li Y,Zhang Y,Liu J,Guo W
Sat Jul 01 00:00:00 EDT 2023
Rapamycin inhibits corneal inflammatory response and neovascularization in a mouse model of corneal alkali burn.
Experimental eye research
Li J,Han J,Shi Y,Liu M
Tue Aug 01 00:00:00 EDT 2023
TGF-β Signaling Activation Confers Anlotinib Resistance in Gastric Cancer.
Pharmaceutical research
Chen J,Hai Y,Hu Q,Chen C,Jiang X,Gao Y
Wed Mar 01 00:00:00 EST 2023
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Molecular cancer
Xing F,Gao H,Chen G,Sun L,Sun J,Qiao X,Xue J,Liu C
Tue Jan 10 00:00:00 EST 2023
Silencing SOX11 Alleviates Allergic Rhinitis by Inhibiting Epithelial-Derived Cytokines.
Balkan medical journal
Jiang L,Wang C,Zhao R,Cao J,Liu Y,Tian L,Liu M
Mon Jan 23 00:00:00 EST 2023
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Biochemical pharmacology
Ren Y,Zhu X,Fu K,Zhang H,Zhao W,Lin Y,Fang Q,Wang J,Chen Y,Guo D
Sun Jan 01 00:00:00 EST 2023
Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells.
FEBS open bio
Hu J,Tan X,Wei X,Hu W,Gao L,Cao X,Yang H,Jiang Z,Li N,Teng L,Liu M
Wed Mar 01 00:00:00 EST 2023
Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice.
Journal of ethnopharmacology
Yao J,Liu J,He Y,Liu L,Xu Z,Lin X,Liu N,Kai G
Fri Sep 15 00:00:00 EDT 2023
ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T-Cell Metabolism.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tan X,Qi C,Zhao X,Sun L,Wu M,Sun W,Gu L,Wang F,Feng H,Huang X,Xie B,Shi Z,Xie P,Wu M,Zhang Y,Chen G
Thu Jun 01 00:00:00 EDT 2023
2-Undecanone alleviates asthma by inhibiting NF-κB pathway.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Song G,Yu S,Zhang Y,Sun M,Zhang B,Peng M
Wed Feb 01 00:00:00 EST 2023
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Life (Basel, Switzerland)
Cafournet C,Zanin S,Guimier A,Hully M,Assouline Z,Barcia G,de Lonlay P,Steffann J,Munnich A,Bonnefont JP,Rötig A,Ruzzenente B,Metodiev MD
Sat Feb 04 00:00:00 EST 2023
RNF123 Mediates Ubiquitination and Degradation of SOCS1 To Regulate Type I Interferon Production during Duck Tembusu Virus Infection.
Journal of virology
Huang S,Cui M,Huang J,Wu Z,Cheng A,Wang M,Zhu D,Chen S,Liu M,Zhao X,Wu Y,Yang Q,Zhang S,Ou X,Mao S,Gao Q,Tian B,Sun D,Yin Z,Jing B,Jia R
Thu Apr 27 00:00:00 EDT 2023
A new acid isolated from V. negundo L. inhibits NLRP3 inflammasome activation and protects against inflammatory diseases.
Frontiers in immunology
Di Q,Zhao X,Lin J,Li X,Li X,Tang H,Zhang R,Xiao W,Chen W
Tue May 09 00:00:00 EDT 2023
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Translational oncology
Ye Z,Xia Y,Li L,Li B,Chen W,Han S,Zhou X,Chen L,Yu W,Ruan Y,Cheng F
Sun Jan 01 00:00:00 EST 2023
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
Oncology reports
Houri A,Mukudai Y,Abe Y,Watanabe M,Nara M,Miyamoto S,Kurihara M,Shimane T,Shirota T
Mon May 01 00:00:00 EDT 2023
The m6A Reader YTHDF1 Promotes Lung Carcinoma Progression via Regulating Ferritin Mediate Ferroptosis in an m6A-Dependent Manner.
Pharmaceuticals (Basel, Switzerland)
Diao H,Tan H,Hu Y,Wang R,Cai P,Huang B,Shao X,Yan M,Yin C,Zhang Y
Wed Jan 25 00:00:00 EST 2023
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Stem cell research & therapy
Wan W,Miao Y,Niu Y,Zhu K,Ma Y,Pan M,Ma B,Wei Q
Mon Mar 20 00:00:00 EDT 2023
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Biochemical pharmacology
Huang P,Zhao H,Pan X,Li J,Pan W,Dai H,Wang J,Xia C,Liu F
Sat Jul 01 00:00:00 EDT 2023
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Environmental pollution (Barking, Essex : 1987)
Zhou G,Wang J,Ren L,Liu J,Li X,Zhang Y,Sang Y,Gao L,Li Y,Sun Z,Zhou X
Wed Feb 01 00:00:00 EST 2023
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Neuroscience letters
Ouyang S,Wang X,Chen Y,Deng L,Yang X,Hu S,Wu S
Thu Mar 16 00:00:00 EDT 2023
Analysis of Promoter Methylation of the Bovine FOXO1 Gene and Its Effect on Proliferation and Differentiation of Myoblasts.
Animals : an open access journal from MDPI
Shi P,Ruan Y,Liu W,Sun J,Xu J,Xu H
Mon Jan 16 00:00:00 EST 2023
Deciphering the molecular mechanism of the THBS1 gene in the TNF signaling axis in glioma stem cells.
Cellular signalling
Chen L,Fang W,Chen W,Wei Y,Ding J,Li J,Lin J,Wu Q
Thu Jun 01 00:00:00 EDT 2023
Research Note: Duck plague virus pUL48 is a late protein that plays an important role in viral replication.
Poultry science
Zhou T,Wang M,Ruan P,Fan D,Cheng A,Zhang W,Tian B,Yang Q,Wu Y,Zhang S,Ou X,Mao S,Huang J,Gao Q,Sun D,Zhao X,Chen S,Liu M,Zhu D,Jia R
Wed Feb 01 00:00:00 EST 2023
JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
Free radical biology & medicine
Sun K,Hou L,Guo Z,Wang G,Guo J,Xu J,Zhang X,Guo F
Mon May 01 00:00:00 EDT 2023
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
Cancer science
Fang Y,Xu Y,Liao W,Ji T,Yu L,Li L,Pan M,Yang D
Sun Jan 01 00:00:00 EST 2023
Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury.
Bioactive materials
Han D,Wang F,Qiao Z,Wang B,Zhang Y,Jiang Q,Liu M,Zhuang Y,An Q,Bai Y,Shangguan J,Zhang J,Liang G,Shen D
Mon May 01 00:00:00 EDT 2023
SERPINF1 Mediates Tumor Progression and Stemness in Glioma.
Genes
Song L,Huo X,Li X,Xu X,Zheng Y,Li D,Zhang J,Wang K,Wang L,Wu Z
Sat Feb 25 00:00:00 EST 2023
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Acta pharmacologica Sinica
Liang JP,He YM,Cui YL,Sun YN,He GS,Zhu ZG,Mao XL
Sat Jul 01 00:00:00 EDT 2023
CENPH overexpression promotes the progression, cisplatin resistance, and poor prognosis of lung adenocarcinoma via the AKT and ERK/P38 pathways.
American journal of cancer research
Li Q,Huang X,Li QY,Tang Y,Liang LB,Luo Q,Gong M,Song YX,Guo Q,Chen C
Mon Jun 12 00:00:00 EDT 2023
Porous composite hydrogels with improved MSC survival for robust epithelial sealing around implants and M2 macrophage polarization.
Acta biomaterialia
Li Y,Zhang J,Wang C,Jiang Z,Lai K,Wang Y,Yang G
Wed Feb 01 00:00:00 EST 2023
Ketogenic diet alleviates renal interstitial fibrosis in UUO mice by regulating macrophage proliferation.
The Journal of nutritional biochemistry
Hu X,Qiu Y,Cao R,Xu C,Lu C,Wang Z,Yang J
Tue Aug 01 00:00:00 EDT 2023
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Cancer science
Wang R,Yu W,Zhu T,Lin F,Hua C,Ru L,Guo P,Wan X,Xue G,Guo Z,Han S,Lv K,Zhang G,Ge H,Guo W,Xu L,Deng W
Thu Jun 01 00:00:00 EDT 2023
Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury.
Frontiers in molecular neuroscience
Han J,Hua Z,Yang WJ,Wang S,Yan F,Wang JN,Sun T
Tue Mar 07 00:00:00 EST 2023
Sp1 promotes tumour progression by remodelling the mitochondrial network in cervical cancer.
Journal of translational medicine
Xu X,Wang X,Chen Q,Zheng A,Li D,Meng Z,Li X,Cai H,Li W,Huang S,Wang F
Sat May 06 00:00:00 EDT 2023
Construction and Characterization of Immortalized Fibroblast Cell Line from Bactrian Camel.
Life (Basel, Switzerland)
Yan M,Yong F,Ji W,Zhang L,Zhao S,Gao Y
Wed Jun 07 00:00:00 EDT 2023
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Small (Weinheim an der Bergstrasse, Germany)
Sun J,Ju F,Jin J,Wang HL,Li ZJ,Sun YC,Chen QZ,Yang QQ,Tan J,Zhou YL
Tue Aug 01 00:00:00 EDT 2023
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
ACS nano
Zhao C,Liu Z,Chang CC,Chen YC,Zhang Q,Zhang XD,Andreou C,Pang J,Liu ZX,Wang DY,Kircher MF,Yang J
Tue Mar 14 00:00:00 EDT 2023
The role of CNPY2 in endothelial injury and inflammation during the progress of atherosclerosis.
Journal of molecular histology
Huang H,Tang N,Li Y,Huo Q,Chen Q,Meng Q
Thu Jun 01 00:00:00 EDT 2023
ML390 inhibits enterovirus 71 replication by targeting de novo pyrimidine biosynthesis pathway.
Antiviral research
Yang Q,Wu C,Zhu G,Ren F,Lin B,Huang R,Hu X,Zhao D,Peng K,Wu Y,Wang Q,Huang C,Zhang D
Sun Jan 01 00:00:00 EST 2023
Lactoferrin Relieves Deoxynivalenol-Induced Oxidative Stress and Inflammatory Response by Modulating the Nrf2/MAPK Pathways in the Liver.
Journal of agricultural and food chemistry
Hu P,Liu Y,Li S,Zhao Y,Gu H,Zong Q,Ahmed AA,Bao W,Liu HY,Cai D
Wed May 31 00:00:00 EDT 2023
Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus by Disrupting Virus Entry.
Pathogens (Basel, Switzerland)
Zhang C,Chen H,Sun L,Zhao P,Qi C,Yang Y,Si A,Qian Y,Jung YS
Mon Jun 19 00:00:00 EDT 2023
MiR-124 Reduced Neuroinflammation after Traumatic Brain Injury by Inhibiting TRAF6.
Neuroimmunomodulation
Yang Y,Ye Y,Fan K,Luo J,Yang Y,Ma Y
Tue Dec 26 00:00:00 EST 2023
PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways.
Inflammation
Huang L,Li Y,Cheng Z,Lv Z,Luo S,Xia Y
Wed Feb 01 00:00:00 EST 2023
Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice.
Brain and behavior
Xu M,Wang X,Wang L,Wang S,Deng J,Wang Y,Li Y,Pan S,Liao A,Tao Y,Tan S
Sat Jul 01 00:00:00 EDT 2023
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
Life sciences
Ma F,Li H,Huo H,Han Q,Liao J,Zhang H,Li Y,Pan J,Hu L,Guo J,Tang Z
Sun Jan 15 00:00:00 EST 2023
Hydrogen sulfide alleviates beryllium sulfate-induced ferroptosis and ferritinophagy in 16HBE cells.
Journal of applied toxicology : JAT
Liu X,Li G,Chen S,Jin H,Liu X,Zhang L,Zhang Z
Tue Aug 01 00:00:00 EDT 2023
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Materials today. Bio
Dai Z,Xia C,Zhao T,Wang H,Tian H,Xu O,Zhu X,Zhang J,Chen P
Wed Feb 01 00:00:00 EST 2023
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
Clinical, cosmetic and investigational dermatology
Ma W,Zhang X,Zhuang L
Tue Jul 04 00:00:00 EDT 2023
Significance of UGT1A6, UGT1A9, and UGT2B7 genetic variants and their mRNA expression in the clinical outcome of renal cell carcinoma.
Molecular and cellular biochemistry
Matsumoto J,Nishimoto A,Watari S,Ueki H,Shiromizu S,Iwata N,Takeda T,Ushio S,Kajizono M,Fujiyoshi M,Koyama T,Araki M,Wada K,Zamami Y,Nasu Y,Ariyoshi N
Tue Aug 01 00:00:00 EDT 2023
RRP Regulates Autophagy through the AMPK Pathway to Alleviate the Effect of Cell Senescence on Atherosclerosis.
Oxidative medicine and cellular longevity
Liu D,Song Y,Song T,Lin L,Zhang L,Yang Q,Niu X,Liang D,Yin J,Yang W,Zhang D
Fri Feb 10 00:00:00 EST 2023
Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivation.
Redox biology
Kong Y,Wu M,Wan X,Sun M,Zhang Y,Wu Z,Li C,Liang X,Gao L,Ma C,Yue X
Sat Jul 01 00:00:00 EDT 2023
Sea Cucumber Hydrolysate Alleviates Immunosuppression and Gut Microbiota Imbalance Induced by Cyclophosphamide in Balb/c Mice through the NF-κB Pathway.
Foods (Basel, Switzerland)
Mao J,Li S,Fu R,Wang Y,Meng J,Jin Y,Wu T,Zhang M
Mon Apr 10 00:00:00 EDT 2023
Profilin1 Promotes Renal Tubular Epithelial Cell Apoptosis in Diabetic Nephropathy Through the Hedgehog Signaling Pathway.
Diabetes, metabolic syndrome and obesity : targets and therapy
Mai L,He G,Chen J,Zhu J,Chen S,Yang H,Zhang M,Hou X,Ke M,Li X
Mon Jun 19 00:00:00 EDT 2023
TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress.
International journal of medical sciences
Yuan H,Li W,Lou N,Yu T,Meng X,Xiao W,Zhang X
Tue Jan 10 00:00:00 EST 2023
Enhanced autophagy reversed aflatoxin B1-induced decrease in lactate secretion of dairy goat Sertoli cells.
Ecotoxicology and environmental safety
Han S,Zhang H,Liu X,Wen F,Li B,Bie Z,Qiu H,Hu J
Sat Jul 01 00:00:00 EDT 2023
KRT17 Promotes T-lymphocyte Infiltration Through the YTHDF2-CXCL10 Axis in Colorectal Cancer.
Cancer immunology research
Liang W,Liu H,Zeng Z,Liang Z,Xie H,Li W,Xiong L,Liu Z,Chen M,Jie H,Zheng X,Huang L,Kang L
Wed Jul 05 00:00:00 EDT 2023
Multimodal rehabilitation promotes axonal sprouting and functional recovery in a murine model of spinal cord injury (SCI).
Neuroscience letters
Wang Y,Luo H,Liu Y,Yang C,Yin Y,Tan B
Tue Jan 31 00:00:00 EST 2023
Inhibition of cGAS aggravated the host inflammatory response to Aspergillus fumigatus.
Experimental lung research
Peng M,Li X,Zhang X,Peng L
Sat Dec 16 00:00:00 EST 2023
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
BMC medicine
Wu T,Zhang X,Liu X,Cai X,Shen T,Pan D,Liang R,Ding R,Hu R,Dong J,Li F,Li J,Xie L,Wang C,Geng S,Yang Z,Xing L,Li Y
Thu Apr 27 00:00:00 EDT 2023
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
Cell death & disease
Zhang L,Fang Z,Cheng G,He M,Lin Y
Mon Feb 20 00:00:00 EST 2023
CENPF promotes the proliferation of renal cell carcinoma in vitro.
Translational andrology and urology
Zhang J,Wang Z,Liu Z,Chen Z,Jiang J,Ji Y,Zhang Y,Zhu H,Zheng B
Tue Feb 28 00:00:00 EST 2023
Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.
Molecular immunology
Jin J,Xu F,Zhang Y,Guan J,Fu J
Wed Mar 01 00:00:00 EST 2023
Exploring the effect of polyamines on NK cell function in colorectal cancer process based on glycolysis.
International immunopharmacology
He H,Song Z,Lin S,Wang Y,Wang G
Sat Apr 01 00:00:00 EDT 2023
NLRP3 activation in microglia contributes to learning and memory impairment induced by chronic lead exposure in mice.
Toxicological sciences : an official journal of the Society of Toxicology
Zhu J,Zhou F,Zhou Q,Xu Y,Li Y,Huang D,Chen L,Liu A,Zou F,Meng X
Tue Jan 31 00:00:00 EST 2023
Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells.
Toxicology
Wang L,Chen Q,Ma R,Zhang B,Yang P,Cao T,Jiao S,Chen H,Lin C,Cai H
Thu Jun 01 00:00:00 EDT 2023
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
Photodiagnosis and photodynamic therapy
Li Y,Wang D,Zhang Z,Wang Y,Zhang Z,Liang Z,Liu F,Chen L
Thu Jun 01 00:00:00 EDT 2023
Discovery of potent and selective PI3Kδ inhibitors bearing amino acid fragments.
Bioorganic chemistry
Lei H,Duan W,Zhang SQ,Feng Y,Ma M,Yuan B,Xin M
Fri Sep 01 00:00:00 EDT 2023
YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis.
Gut microbes
Li N,Xu X,Zhan Y,Fei X,Ouyang Y,Zheng P,Zhou Y,He C,Xie C,Hu Y,Hong J,Lu N,Ge Z,Zhu Y
Mon Mar 27 00:00:00 EDT 2023
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC.
Molecular therapy. Nucleic acids
Zhang X,Sun J,Zhang P,Wen T,Wang R,Liang L,Yang Z,Li J,Zhang J,Che B,Feng X,Liu X,Han H,Yan X
Tue Jun 13 00:00:00 EDT 2023
Caveolae-associated protein 3 promotes adipogenic differentiation of porcine preadipocytes by promoting extracellular signal-regulated kinase phosphorylation.
Animal science journal = Nihon chikusan Gakkaiho
Shi M,Yang S,Huang X,Wang S,Li W,Yun J,Lu C,Yang Y,Cai C,Gao P,Guo X,Li B,Cao G
Mon Mar 20 00:00:00 EDT 2023
Knock-down of PGM1 inhibits cell viability, glycolysis, and oxidative phosphorylation in glioma under low glucose condition via the Myc signaling pathway.
Biochemical and biophysical research communications
Liu S,Deng Y,Yu Y,Xia X
Sun May 14 00:00:00 EDT 2023
Persistent Müllerian duct syndrome in an assisted reproductive patient: a novel variant impairs the biosynthesis and secretion of anti-Müllerian hormone (AMH).
Asian journal of andrology
Du Q,Qiu C,Zhang L,Wang QY,Hong K,Liu XL
Fri Jul 21 00:00:00 EDT 2023
Ccdc25 regulates neurogenesis during the brain development.
Developmental neurobiology
Wang C,Qin J,Jiao J,Ji F
Mon May 22 00:00:00 EDT 2023
Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC.
Hepatology communications
Yu HQ,Li F,Xiong H,Fang L,Zhang J,Bie P,Xie CM
Sat Jul 01 00:00:00 EDT 2023
Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach.
Frontiers in molecular biosciences
Reivan Ortiz GG,Ciongradi CI,Chaitanya MVNL,Narayanan J,Mohany M,Al-Rejaie SS,Arias-Gonzáles JL,Sârbu I,Assefi M,Akram SV,Döğüş Y,Bahrami A,Akhavan-Sigari R
Tue Jun 20 00:00:00 EDT 2023
Intraoperative blood auto-transfusion restrained the malignancy of Liver Cancer via regulating functions of tumor cells and Kuffer cells.
Biotechnology & genetic engineering reviews
Yao N,Wu M,You L,Xu J,Liu T,Wang J,Li Z,Guo J,Sun Y
Thu May 18 00:00:00 EDT 2023
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Journal of ethnopharmacology
Zhang X,Wang S,Jin Y,Wang J,Wang R,Yang X,Zhang S,Yan T,Jia Y
Tue May 23 00:00:00 EDT 2023
Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation.
Marine drugs
Abdelwahed KS,Siddique AB,Ebrahim HY,Qusa MH,Mudhish EA,Rad AH,Zerfaoui M,Abd Elmageed ZY,El Sayed KA
Tue Mar 28 00:00:00 EDT 2023
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Toxicology
Liu M,Yu Z,Yang F,Zhao Z,Zhou M,Wang C,Zhang B,Liang G,Liu X,Shao J
Tue Aug 01 00:00:00 EDT 2023
Regulation of telomere silencing by the core histones-autophagy-Sir2 axis.
Life science alliance
Mei Q,Yu Q,Li X,Chen J,Yu X
Wed Mar 01 00:00:00 EST 2023
ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response.
Molecular medicine (Cambridge, Mass.)
Liu Y,Zhang L,Zhang S,Liu J,Li X,Yang K,Yang D,Liu Y,Sun L,Liu F,Xiao L
Mon Apr 24 00:00:00 EDT 2023
SOX9/NFIA promotes human ovarian cancer metastasis through the Wnt/β-catenin signaling pathway.
Pathology, research and practice
Lu R,Tang P,Zhang D,Lin S,Li H,Feng X,Sun M,Zhang H
Tue Aug 01 00:00:00 EDT 2023
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
International immunopharmacology
Wang P,Li T,Niu C,Sun S,Liu D
Wed Mar 01 00:00:00 EST 2023
Integrated analysis of cell-specific gene expression in peripheral blood using ISG15 as a marker of rejection in kidney transplantation.
Frontiers in immunology
Zhang Z,Qin Y,Wang Y,Li S,Hu X
Fri Mar 31 00:00:00 EDT 2023
A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways.
Journal of oncology
Duan SF,Zhang MM,Dong Q,Yang B,Liu W,Zhang X,Yu HL,Zhang SH,Khan NH,Wu DD,Zhang XJ,Cen J
Sat Mar 18 00:00:00 EDT 2023
ITGB1-mediated molecular landscape and cuproptosis phenotype induced the worse prognosis in diffuse gastric cancer.
Frontiers in oncology
Zhu X,Chen H,Li H,Ren H,Ye C,Xu K,Liu J,Du F,Zhang Z,Liu Y,Xie X,Wang M,Ma T,Chong W,Shang L,Li L
Tue Apr 04 00:00:00 EDT 2023
Plasma microRNA expression profiles associated with zinc exposure and type 2 diabetes mellitus: Exploring potential role of miR-144-3p in zinc-induced insulin resistance.
Environment international
Ye Z,Cheng M,Fan L,Ma J,Zhang Y,Gu P,Xie Y,You X,Zhou M,Wang B,Chen W
Wed Feb 01 00:00:00 EST 2023
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Nutrients
Guo TT,Zhang Z,Sun Y,Zhu RY,Wang FX,Ma LJ,Jiang L,Liu HD
Mon Feb 13 00:00:00 EST 2023
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Cell death & disease
Hong X,Ma N,Li D,Zhang M,Dong W,Huang J,Ci X,Zhang S
Fri Feb 10 00:00:00 EST 2023
Knockdown of CENPN Inhibits Glucose Metabolism and Induces G1 Arrest in Esophageal Cancer Cells by Regulating PI3K/AKT Signaling Pathway.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Xu S,Wei X
Tue Aug 01 00:00:00 EDT 2023
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208.
Cell death & disease
Han J,Chen X,Wang J,Liu B
Fri Feb 03 00:00:00 EST 2023
SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway.
BMC cancer
Shang K,Ma N,Che J,Li H,Hu J,Sun H,Cao B
Tue Apr 11 00:00:00 EDT 2023
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
Translational stroke research
Wang Z,Zhang S,Du J,Lachance BB,Chen S,Polster BM,Jia X
Sun Oct 01 00:00:00 EDT 2023
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression.
International immunopharmacology
Li Y,Shen B,Lv C,Zhu X,Naren Q,Xu D,Chen H,Wu F
Sun Jan 01 00:00:00 EST 2023
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Cell biology international
Zhong B,Zhu Q,Wang L,Wang F,Zheng Y,Lin S,Cheng X
Tue Aug 01 00:00:00 EDT 2023
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.
PLoS pathogens
Diao F,Jiang C,Sun Y,Gao Y,Bai J,Nauwynck H,Wang X,Yang Y,Jiang P,Liu X
Wed Mar 01 00:00:00 EST 2023
The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma.
Drug delivery
Xu H,Zhang Y,Li L,Ren Y,Qian F,Wang L,Ma H,Quan A,Liu H,Yu R
Fri Dec 01 00:00:00 EST 2023
18β-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-κB and HMGB1 Signalling Suppression in PIEC Cells.
Infection and drug resistance
Lu Q,Han W,Wen D,Guo P,Liu Y,Wu Z,Fu S,Ye C,Wang X,Qiu Y
Tue Jul 18 00:00:00 EDT 2023
Brown-fat-mediated tumour suppression by cold-altered global metabolism.
Nature
Seki T,Yang Y,Sun X,Lim S,Xie S,Guo Z,Xiong W,Kuroda M,Sakaue H,Hosaka K,Jing X,Yoshihara M,Qu L,Li X,Chen Y,Cao Y
Mon Aug 01 00:00:00 EDT 2022
A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism.
Nucleic acids research
Meng F,Jia Z,Zheng J,Ji Y,Wang J,Xiao Y,Fu Y,Wang M,Ling F,Guan MX
Fri Sep 09 00:00:00 EDT 2022
Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation.
Frontiers in nutrition
Li H,Xi Y,Liu H,Xin X
Tue Sep 13 00:00:00 EDT 2022
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Journal of ginseng research
Pan H,Yang L,Bai H,Luo J,Deng Y
Thu Sep 01 00:00:00 EDT 2022
G3BP2, a stress granule assembly factor, is dispensable for spermatogenesis in mice.
PeerJ
Yun D,Zhou L,Shi J,Li X,Wu X,Sun F
Sat Jan 21 00:00:00 EST 2023
Antidepressant effects of total alkaloids of Fibraurea recisa on improving corticosterone-induced apoptosis of HT-22 cells and chronic unpredictable mild stress-induced depressive-like behaviour in mice.
Pharmaceutical biology
He Z,Yu H,Wu H,Su L,Shi K,Zhao Y,Zong Y,Chen W,Du R
Thu Dec 01 00:00:00 EST 2022
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
Cancer cell international
Tong Q,Yi M,Kong P,Xu L,Huang W,Niu Y,Gan X,Zhan H,Tian R,Yan D
Tue Sep 06 00:00:00 EDT 2022
African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.
Viruses
Wang Q,Zhou L,Wang J,Su D,Li D,Du Y,Yang G,Zhang G,Chu B
Tue Feb 15 00:00:00 EST 2022
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
BioMed research international
Zou X,Li T,Mao Y,Zhu M,Chen X,Niu J,Dong T,Jiang J,Yang X
Wed Nov 23 00:00:00 EST 2022
SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.
Journal of cellular and molecular medicine
Chen S,Li QH,Chen X,Bao HJ,Wu W,Shen F,Lu BF,Jiang RQ,Zong ZH,Zhao Y
Sat Oct 01 00:00:00 EDT 2022
A New Long Noncoding RNA, MAHAT, Inhibits Replication of Porcine Reproductive and Respiratory Syndrome Virus by Recruiting DDX6 To Bind to ZNF34 and Promote an Innate Immune Response.
Journal of virology
Liu Y,Liu X,Bai J,Sun Y,Nauwynck H,Wang X,Yang Y,Jiang P
Wed Sep 28 00:00:00 EDT 2022
Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway.
Disease markers
Lei Y,Chan M,Liu H,Lyu W,Chen L,Zhong Y,Gan H,Wang M,Qi M,Guo Y,Liu J,Zhang E
Fri Jul 29 00:00:00 EDT 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 EDT 2022
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study.
Clinical proteomics
Zhou H,Gan X,He S,Wang Y,Zhang S,Chen J,Zhou Y,Hou C,Hua L,Zhang Q,Jia E
Thu Nov 03 00:00:00 EDT 2022
Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization.
Drug delivery
Bi QC,Tang JJ,Zhao J,Lv YF,Deng ZQ,Chen H,Xu YH,Xie CS,Liang QR,Luo RG,Tang Q
Thu Dec 01 00:00:00 EST 2022
Pterostilbene and Its Derivative 3'-Hydroxypterostilbene Ameliorated Nonalcoholic Fatty Liver Disease Through Synergistic Modulation of the Gut Microbiota and SIRT1/AMPK Signaling Pathway.
Journal of agricultural and food chemistry
Tsai HY,Shih YY,Yeh YT,Huang CH,Liao CA,Hu CY,Nagabhushanam K,Ho CT,Chen YK
Wed Apr 27 00:00:00 EDT 2022
Trans-anethole Ameliorates Intestinal Injury Through Activation of Nrf2 Signaling Pathway in Subclinical Necrotic Enteritis-Induced Broilers.
Frontiers in veterinary science
Yu C,Tong Y,Li Q,Wang T,Yang Z
Sat May 07 00:00:00 EDT 2022
Mulberry Leaf Flavonoids Inhibit Liver Inflammation in Type 2 Diabetes Rats by Regulating TLR4/MyD88/NF-κB Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Duan Y,Dai H,An Y,Cheng L,Shi L,Lv Y,Li H,Wang C,He C,Zhang H,Huang Y,Fu W,Meng Y,Zhao B
Tue Jul 19 00:00:00 EDT 2022
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway.
International journal of biological sciences
Wen H,Zhong Y,Yin Y,Qin K,Yang L,Li D,Yu W,Yang C,Deng Z,Hong K
Thu May 12 00:00:00 EDT 2022
A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator.
European journal of medicinal chemistry
Guo J,Cheng M,Liu P,Cao D,Luo J,Wan Y,Fang Y,Jin Y,Xie SS,Liu J
Tue Nov 15 00:00:00 EST 2022
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
CNS neuroscience & therapeutics
Yang QY,Li XW,Yang R,Qin TY,Long H,Zhang SB,Zhang F
Sat Oct 01 00:00:00 EDT 2022
Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway.
Parasites & vectors
Obed C,Wu M,Chen Y,An R,Cai H,Luo Q,Yu L,Wang J,Liu F,Shen J,Du J
Tue Aug 02 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Life sciences
Zhu M,Niu J,Jiang J,Dong T,Chen Y,Yang X,Liu P
Tue Mar 15 00:00:00 EDT 2022
Maternal Inflammation Exaggerates Offspring Susceptibility to Cerebral Ischemia-Reperfusion Injury via the COX-2/PGD2/DP2 Pathway Activation.
Oxidative medicine and cellular longevity
Li Y,Luo W,Zhang J,Luo Y,Han W,Wang H,Xia H,Chen Z,Yang Y,Chen Q,Li H,Yang L,Hu C,Huang H,Peng Z,Tan X,Li M,Yang J
Wed Apr 20 00:00:00 EDT 2022
Preliminary Evaluation of Artificial Intelligence-Based Anti-Hepatocellular Carcinoma Molecular Target Study in Hepatocellular Carcinoma Diagnosis Research.
BioMed research international
Wang Y,Wei C,Deng X,Gao S,Chen J
Wed Oct 05 00:00:00 EDT 2022
ASFV pD345L protein negatively regulates NF-κB signalling by inhibiting IKK kinase activity.
Veterinary research
Chen H,Wang Z,Gao X,Lv J,Hu Y,Jung YS,Zhu S,Wu X,Qian Y,Dai J
Sat Apr 23 00:00:00 EDT 2022
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Journal of translational medicine
Qiu D,Song S,Wang Y,Bian Y,Wu M,Wu H,Shi Y,Duan H
Fri Jan 28 00:00:00 EST 2022
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Clinics (Sao Paulo, Brazil)
Wang X,Fu Y,Xing Y
Mon Oct 31 00:00:00 EDT 2022
Liver fibrosis alters the molecular structures of hepatic glycogen.
Carbohydrate polymers
Wan Y,Hu Z,Liu Q,Wang L,Sullivan MA,Gilbert RG
Tue Feb 15 00:00:00 EST 2022
Organophosphate flame retardant TDCPP: A risk factor for renal cancer?
Chemosphere
Zhou X,Zhou X,Yao L,Zhang X,Cong R,Luan J,Zhang T,Song N
Sat Oct 01 00:00:00 EDT 2022
Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.
Andrology
Wang J,Song J,Song G,Feng Y,Pan J,Yang X,Xin Z,Hu P,Sun T,Liu K,Xu W,Wang T,Wang S,Liu J,Ruan Y
Fri Jul 01 00:00:00 EDT 2022
A single-beam of light priming the immune responses and boosting cancer photoimmunotherapy.
Journal of controlled release : official journal of the Controlled Release Society
Sun Y,Han R,Wang J,Qin Y,Ren Z,Feng X,Liu Q,Wang X
Sat Oct 01 00:00:00 EDT 2022
Deciphering the tumor microenvironment cell-infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC.
JCI insight
Chen H,Zhang T,Zhang Y,Wu H,Fang Z,Liu Y,Chen Y,Wang Z,Jia S,Ji X,Shang L,Du F,Liu J,Lu M,Chong W
Wed Jun 22 00:00:00 EDT 2022
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Frontiers in pharmacology
Qin K,Tang H,Ren Y,Yang D,Li Y,Huang W,Wu Y,Yin Z
Tue Aug 30 00:00:00 EDT 2022
DDX47 promotes cell proliferation and migration in lung adenocarcinoma.
Pathology, research and practice
Chen Y,Zeng L,Wang W,Yuan J,Sun R,Yang S
Wed Jun 01 00:00:00 EDT 2022
Immunity of two novel hepatitis C virus polyepitope vaccines.
Vaccine
Feng T,Li M,Zhang L,Li S,Yang Z,Kang L,Guo Y,Kong L,Wang T
Wed Oct 12 00:00:00 EDT 2022
Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development.
BMC medicine
Zhang D,Yang Y,Yang Y,Liu J,Zhu T,Huang H,Zhou C
Wed Jul 27 00:00:00 EDT 2022
U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells.
Bioengineered
Li Y,Chen S,Zhang X,Zhuo N
Fri Apr 01 00:00:00 EDT 2022
ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation.
Redox biology
Zhang J,Liu L,Zhang Y,Yuan Y,Miao Z,Lu K,Zhang X,Ni R,Zhang H,Zhao Y,Wang X
Thu Dec 01 00:00:00 EST 2022
Ghrelin ameliorates diabetes-associated behavioral deficits and NLRP3 inflammasome activation via autophagic flux enhancement.
Pharmacological research
Han W,Cui C,Zhang H,Guo Y,Xie D,Zhang W,Wang C,Yang M,Jiang P
Sun May 01 00:00:00 EDT 2022
PCV2 and PRV Coinfection Induces Endoplasmic Reticulum Stress via PERK-eIF2α-ATF4-CHOP and IRE1-XBP1-EDEM Pathways.
International journal of molecular sciences
Chen S,Li X,Zhang X,Niu G,Yang L,Ji W,Zhang L,Ren L
Tue Apr 19 00:00:00 EDT 2022
Salecan ameliorates liver injury by regulating gut microbiota and its metabolites.
Food & function
Li P,Liu Y,Zhao J,Pan W,He Y,Fu S,Liu Y,Xu YJ
Mon Nov 14 00:00:00 EST 2022
Decitabine attenuates ischemic stroke by reducing astrocytes proliferation in rats.
PloS one
Zhang Q,Li D,Zhao H,Zhang X
Thu Aug 04 00:00:00 EDT 2022
Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells.
Drug delivery
Wang Y,Ouyang Q,Chang X,Yang M,He J,Tian Y,Sheng J
Thu Dec 01 00:00:00 EST 2022
Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yi Y,Hao Z,Sun P,Fan K,Yin W,Guo J,Zheng X,Sun N,Li H
Thu Dec 01 00:00:00 EST 2022
Ibandronate promotes autophagy by inhibiting Rac1-mTOR signaling pathway in vitro and in vivo.
Cell death discovery
Han J,Yang J,Wang Q,Yin X,Sun Z,Huang C,Chen G,Zheng L,Jiang D
Sat Apr 09 00:00:00 EDT 2022
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
mBio
Shi X,Li X,Xu Z,Shen L,Ding Y,Chen S,Mao L,Liu W,Xu J
Tue Dec 20 00:00:00 EST 2022
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
mBio
Shi X,Li X,Xu Z,Shen L,Ding Y,Chen S,Mao L,Liu W,Xu J
Tue Dec 20 00:00:00 EST 2022
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
mBio
Shi X,Li X,Xu Z,Shen L,Ding Y,Chen S,Mao L,Liu W,Xu J
Tue Dec 20 00:00:00 EST 2022
ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins.
mBio
Shi X,Li X,Xu Z,Shen L,Ding Y,Chen S,Mao L,Liu W,Xu J
Tue Dec 20 00:00:00 EST 2022
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Oxidative medicine and cellular longevity
Jiang QY,Li JM,Jing MR,Zhang YX,Zhang QQ,Cai CB,Wang D,Qi HW,Li T,Li YZ,Ji XY,Wu DD
Fri Jul 08 00:00:00 EDT 2022
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Frontiers in pharmacology
Ge Y,Zhen F,Liu Z,Feng Z,Wang G,Zhang C,Wang X,Sun Y,Zheng X,Bai Y,Yao R
Wed Apr 13 00:00:00 EDT 2022
Substitution of SERCA2 Cys674 accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
British journal of pharmacology
Wang L,Yang Z,Wang S,Que Y,Shu X,Wu F,Liu G,Li S,Hu P,Chen H,Shi J,Tong X
Thu Sep 01 00:00:00 EDT 2022
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Cell death & disease
Song S,Shi C,Bian Y,Yang Z,Mu L,Wu H,Duan H,Shi Y
Sat Jul 30 00:00:00 EDT 2022
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Biochemical and biophysical research communications
Zheng L,Chen X,Yin Q,Gu J,Chen J,Chen M,Zhang Y,Dong M,Jiang H,Yin N,Chen H,Li X
Tue Dec 20 00:00:00 EST 2022
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Mediators of inflammation
Liu WZ,Ma ZJ,Kang JH,Lin AX,Wang ZH,Chen HW,Guo XD,He XG,Kang XW
Tue Aug 16 00:00:00 EDT 2022
Oroxin A ameliorates the oleic acid-induced A549 cell injury through the suppression of pyroptosis and degradation of alveolar surfactant.
Anais da Academia Brasileira de Ciencias
Huang J,Chen C,Xie J,Zhai K,Wei S,Cheng X,Zhang R
Thu Dec 15 00:00:00 EST 2022
Moxidectin induces autophagy arrest in colorectal cancer.
Medical oncology (Northwood, London, England)
Mao Y,Xie H,Shu D,Cheng L,Lan J,Pan K
Thu Sep 29 00:00:00 EDT 2022
Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis.
International journal of environmental research and public health
Xu X,Li Y,Niu Z,Xia J,Dai K,Wang C,Yao W,Guo Y,Deng X,He J,Deng M,Si H,Hao C
Wed Jun 01 00:00:00 EDT 2022
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
Cell death & disease
Li M,Zhao X,Yong H,Xu J,Qu P,Qiao S,Hou P,Li Z,Chu S,Zheng J,Bai J
Wed Feb 02 00:00:00 EST 2022
Bisphenol A impairs macrophages through inhibiting autophagy via AMPK/mTOR signaling pathway and inducing apoptosis.
Ecotoxicology and environmental safety
Wu M,Cong Y,Wang K,Yu H,Zhang X,Ma M,Duan Z,Pei X
Fri Apr 01 00:00:00 EDT 2022
Corilagin induces apoptosis and inhibits autophagy of HL‑60 cells by regulating miR‑451/HMGB1 axis.
Molecular medicine reports
Jia S,He D,Liang X,Cheng P,Liu J,Chen M,Wang C,Zhang H,Meng C
Sat Jan 01 00:00:00 EST 2022
Taurine protects R28 cells from hypoxia/re-oxygenation-induced damage via regulation of mitochondrial energy metabolism.
Amino acids
Lu W,Yang Y,Gao S,Wu J,Sun X
Thu Dec 01 00:00:00 EST 2022
Nicotinamide riboside promotes Mfn2-mediated mitochondrial fusion in diabetic hearts through the SIRT1-PGC1α-PPARα pathway.
Free radical biology & medicine
Hu L,Guo Y,Song L,Wen H,Sun N,Wang Y,Qi B,Liang Q,Geng J,Liu X,Fu F,Li Y
Fri Apr 01 00:00:00 EDT 2022
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
ACS omega
Lv C,Li S,Zhao J,Yang P,Yang C
Tue Apr 05 00:00:00 EDT 2022
Low expression of microRNA-125b enhances the expression of STAT3 and contributes to cholesteatoma growth.
Archives of medical science : AMS
Zang J,Yang B,Feng S,Jiang X
Sat Dec 03 00:00:00 EST 2022
The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells.
International journal of molecular sciences
Liu X,Shi Q,Choudhry N,Zhang T,Liu H,Zhang S,Zhang J,Yang D
Tue Oct 11 00:00:00 EDT 2022
HNRNPK/CLCN3 axis facilitates the progression of LUAD through CAF-tumor interaction.
International journal of biological sciences
Li Y,Yang Y,Ma Q,Cheng H,Wang H,Ma C,Li F,Zhao S,Li X,Qi Y,Gu Z
Tue Nov 29 00:00:00 EST 2022
HNRNPK/CLCN3 axis facilitates the progression of LUAD through CAF-tumor interaction.
International journal of biological sciences
Li Y,Yang Y,Ma Q,Cheng H,Wang H,Ma C,Li F,Zhao S,Li X,Qi Y,Gu Z
Tue Nov 29 00:00:00 EST 2022
Inhibition of APE1 Expression Enhances the Antitumor Activity of Olaparib in Triple-Negative Breast Cancer.
Evidence-based complementary and alternative medicine : eCAM
Jian D,Li XM,Dai N,Liang DD,Zhang G,Mao CY,Wang D,Song GB,Li MX,Luo H
Sat Jul 16 00:00:00 EDT 2022
Glycogen metabolism reprogramming promotes inflammation in coal dust-exposed lung.
Ecotoxicology and environmental safety
Wang W,Mu M,Zou Y,Deng S,Lu Y,Li Q,Li Z,Tao H,Wang Y,Tao X
Thu Sep 01 00:00:00 EDT 2022
Poldip2 knockdown protects against lipopolysaccharide-induced acute lung injury via Nox4/Nrf2/NF-κB signaling pathway.
Frontiers in pharmacology
Wang Y,Wang W,Zhou S,Wang Y,Cudjoe O,Cha Y,Wang C,Cao X,Liu W,Jin K
Tue Sep 20 00:00:00 EDT 2022
Ubiquitin-specific protease 47 regulates intestinal inflammation through deubiquitination of TRAF6 in epithelial cells.
Science China. Life sciences
Lei H,Yang L,Xu H,Wang Z,Li X,Liu M,Wu Y
Mon Aug 01 00:00:00 EDT 2022
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Journal of agricultural and food chemistry
Bai X,Liu X,Li S,An H,Kang X,Guo S
Wed Mar 30 00:00:00 EDT 2022
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Cell biology international
Zhou Z,Dong Y,Li N,Niu M,Wang S,Zhou Y,Sun Z,Chu P,Tang Z
Tue Nov 01 00:00:00 EDT 2022
Calycosin suppresses colorectal cancer progression by targeting ERβ, upregulating PTEN, and inhibiting PI3K/Akt signal pathway.
Cell biology international
Zhu L,Liu S,Liao YF,Sheng YM,He JC,Cai ZX,Man Q,Wu YY
Thu Sep 01 00:00:00 EDT 2022
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Cell death & disease
Hu Y,Xie Q,Wu X,Liu W,Li D,Li C,Zhao W,Chen L,Zheng Z,Li G,Guo J
Sat Oct 08 00:00:00 EDT 2022
Activation of the NLRP3 inflammasome by RAC1 mediates a new mechanism in diabetic nephropathy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ying C,Zhou Z,Dai J,Wang M,Xiang J,Sun D,Zhou X
Tue Feb 01 00:00:00 EST 2022
Dye-Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On-Demand Gas Therapy of Glioblastoma Guided by NIR-II Fluorescence Imaging.
Advanced healthcare materials
Liu Z,Yun B,Han Y,Jiang Z,Zhu H,Ren F,Li Z
Tue Feb 01 00:00:00 EST 2022
Essential role of MALAT1 in reducing traumatic brain injury.
Neural regeneration research
Wu N,Cheng CJ,Zhong JJ,He JC,Zhang ZS,Wang ZG,Sun XC,Liu H
Mon Aug 01 00:00:00 EDT 2022
Glucagon-like Peptide 1 Receptor Activation Inhibits Microglial Pyroptosis via Promoting Mitophagy to Alleviate Depression-like Behaviors in Diabetic Mice.
Nutrients
Yang F,Wang X,Qi J,Zhang K,Jiang Y,Feng B,Lv T,Yang L,Yang Q,Zhao M,Liu S,Ma X
Wed Dec 21 00:00:00 EST 2022
IL-22 Protects against Biliary Ischemia-Reperfusion Injury after Liver Transplantation via Activating STAT3 and Reducing Apoptosis and Oxidative Stress Levels In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Bai Y,Wu H,Zhang J,Zhang S,Zhang Z,Wang H,Zhang Y,Shen Z
Mon May 23 00:00:00 EDT 2022
Paeoniflorin-6'-o-benzene sulfonate ameliorates the progression of adjuvant-induced arthritis by inhibiting the interaction between Ahr and GRK2 of fibroblast-like synoviocytes.
International immunopharmacology
Zhang BJ,Wang YY,Jia CY,Li SS,Wang XW,Xu Y,Chen AY,Xu HP,Wang C,Yang ZY,Wei W,Chang Y
Fri Jul 01 00:00:00 EDT 2022
Weighted gene co-expression network indicates that the DYNLL2 is an important regulator of chicken breast muscle development and is regulated by miR-148a-3p.
BMC genomics
Li Y,Yuan P,Fan S,Zhai B,Jin W,Li D,Li H,Sun G,Han R,Liu X,Tian Y,Li G,Kang X
Mon Apr 04 00:00:00 EDT 2022
Genistein Alleviates Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus by Activating the Sirt1/Nrf2 Pathway in High Salt-Induced Hypertension.
Cardiovascular toxicology
Niu LG,Sun N,Liu KL,Su Q,Qi J,Fu LY,Xin GR,Kang YM
Tue Nov 01 00:00:00 EDT 2022
Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c-Myc G-Quadruplex Stabilizers to Suppress c-Myc Transcription and Myeloma Growth.
Molecular informatics
Zhang J,Wang T,Geng X,Liu L,Gao J
Sat Oct 01 00:00:00 EDT 2022
Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.
Cell reports
Zhang M,Su L,Wang W,Li C,Liang Q,Ji F,Jiao J
Tue Sep 13 00:00:00 EDT 2022
A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5.
Journal of experimental & clinical cancer research : CR
Song J,Zheng J,Liu X,Dong W,Yang C,Wang D,Ruan X,Zhao Y,Liu L,Wang P,Zhang M,Liu Y
Tue May 10 00:00:00 EDT 2022
Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.
Frontiers in molecular neuroscience
Kuang H,Liu T,Jiao C,Wang J,Wu S,Wu J,Peng S,Davidson AM,Zeng SX,Lu H,Mostany R
Fri Apr 29 00:00:00 EDT 2022
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis.
JCI insight
Yang M,Li S,Huang L,Zhao R,Dai E,Jiang X,He Y,Lu J,Peng L,Liu W,Zhang Z,Jiang D,Zhang Y,Jiang Z,Yang Y,Zhao P,Zhu X,Ding X,Yang Z
Fri Jul 22 00:00:00 EDT 2022
Myeloid peroxisome proliferator-activated receptor α deficiency accelerates liver regeneration via IL-6/STAT3 pathway after 2/3 partial hepatectomy in mice.
Hepatobiliary surgery and nutrition
Xie G,Song Y,Li N,Zhang Z,Wang X,Liu Y,Jiao S,Wei M,Yu B,Wang Y,Wang H,Qu A
Fri Apr 01 00:00:00 EDT 2022
Mettl14-Mediated m6A Modification Is Essential for Germinal Center B Cell Response.
Journal of immunology (Baltimore, Md. : 1950)
Huang H,Zhang G,Ruan GX,Li Y,Chen W,Zou J,Zhang R,Wang J,Ji SJ,Xu S,Ou X
Fri Apr 15 00:00:00 EDT 2022
TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
Cell death & disease
Yi L,Hu Y,Wu Z,Li Y,Kong M,Kang Z,Zuoyuan B,Yang Z
Mon Jul 11 00:00:00 EDT 2022
Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Extracellular Vesicles Promotes Hepatic Stellate Cell Activation, Liver Fibrosis and β-Catenin Signaling Pathway.
Frontiers in physiology
Wang T,Zhang C,Meng X,Zhu B,Wang S,Yuan W,Zhang S,Xu J,Zhang C
Fri Mar 04 00:00:00 EST 2022
Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Liu S,Jin Z,Xia R,Zheng Z,Zha Y,Wang Q,Wan X,Yang H,Cai J
Thu Mar 17 00:00:00 EDT 2022
The hsa-miR-214-3p/ATGL axis regulates aberrant lipolysis to promote acute myeloid leukemia progression via PPARα in vitro.
Biochemical and biophysical research communications
Li Y,Yuan S,Wu W,Zhou J,Zhang P,Li D,Zhang Y,Lou S
Sat Jun 11 00:00:00 EDT 2022
Alzheimer's risk factor FERMT2 promotes the progression of colorectal carcinoma via Wnt/β-catenin signaling pathway and contributes to the negative correlation between Alzheimer and cancer.
PloS one
Xia W,Gao Z,Jiang X,Jiang L,Qin Y,Zhang D,Tian P,Wang W,Zhang Q,Zhang R,Zhang N,Xu S
Wed Dec 21 00:00:00 EST 2022
Hydroxysafflor Yellow A Blocks HIF-1α Induction of NOX2 and Protects ZO-1 Protein in Cerebral Microvascular Endothelium.
Antioxidants (Basel, Switzerland)
Li Y,Liu XT,Zhang PL,Li YC,Sun MR,Wang YT,Wang SP,Yang H,Liu BL,Wang M,Gao W,Li P
Thu Apr 07 00:00:00 EDT 2022
The BDNF-TrkB signaling pathway in the rostral anterior cingulate cortex is involved in the development of pain aversion in rats with bone cancer via NR2B and ERK-CREB signaling.
Brain research bulletin
Li J,Wang X,Wang H,Wang R,Guo Y,Xu L,Zhang G,Wu J,Wang G
Fri Jul 01 00:00:00 EDT 2022
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Pharmaceutical biology
Bian Y,Xue M,Guo X,Jiang W,Zhao Y,Zhang Z,Wang X,Hu Y,Zhang Q,Dun W,Zhang L
Thu Dec 01 00:00:00 EST 2022
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
Frontiers in oncology
Wang X,Wang Y,Sun F,Xu Y,Zhang Z,Yang C,Zhang L,Lou G
Sun Jul 31 00:00:00 EDT 2022
Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood-Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations.
International journal of molecular sciences
Li P,Yang Y,Lin Z,Hong S,Jiang L,Zhou H,Yang L,Zhu L,Liu X,Liu L
Mon Jul 11 00:00:00 EDT 2022
Overexpression of heat shock protein 70 induces apoptosis of intestinal epithelial cells in heat-stressed pigs: A proteomics approach.
Journal of thermal biology
Yong Y,Li J,Yu T,Fang B,Liu X,Yu Z,Ma X,Gooneratne R,Abd El-Aty AM,Ju X
Mon Aug 01 00:00:00 EDT 2022
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
Frontiers in oncology
Li Y,Wang H,Wan J,Ma Q,Qi Y,Gu Z
Tue Jul 26 00:00:00 EDT 2022
Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang W,Su L,Wang Y,Li C,Ji F,Jiao J
Wed Jun 01 00:00:00 EDT 2022
HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.
Cell biology international
Liu S,Song L,Yao H,Zhang L
Tue Mar 01 00:00:00 EST 2022
HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.
Cell biology international
Liu S,Song L,Yao H,Zhang L
Tue Mar 01 00:00:00 EST 2022
High expression of Sam68 contributes to metastasis by regulating vimentin expression and a motile phenotype in oral squamous cell carcinoma.
Oncology reports
Komiyama T,Kuroshima T,Sugasawa T,Fujita SI,Ikami Y,Hirai H,Tsushima F,Michi Y,Kayamori K,Higashino F,Harada H
Sat Oct 01 00:00:00 EDT 2022
Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro.
Frontiers in endocrinology
Ma Y,Zhou Q,Zhao P,Lv X,Gong C,Gao J,Liu J
Tue Feb 14 00:00:00 EST 2023
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Cellular and molecular gastroenterology and hepatology
Huang X,Yao Y,Hou X,Wei L,Rao Y,Su Y,Zheng G,Ruan XZ,Li D,Chen Y
Mon Jun 20 00:00:00 EDT 2022
Upregulated LINC01088 facilitates malignant phenotypes and immune escape of colorectal cancer by regulating microRNAs/G3BP1/PD-L1 axis.
Journal of cancer research and clinical oncology
Li C,Pan B,Wang X,Liu X,Qin J,Gao T,Sun H,Pan Y,Wang S
Mon Aug 01 00:00:00 EDT 2022
Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy.
Pharmaceuticals (Basel, Switzerland)
Wang N,Li Y,He F,Liu S,Liu Y,Peng J,Liu J,Yu C,Wang S
Mon Aug 29 00:00:00 EDT 2022
Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease.
Frontiers in pharmacology
Wang X,Liu XQ,Jiang L,Huang YB,Zeng HX,Zhu QJ,Qi XM,Wu YG
Sat Sep 24 00:00:00 EDT 2022
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway.
Injury
Zhang Y,Zhu Q,Fang Q,Yin D,Duan Y,Xue G,Ma N,Cai Y,He M
Wed Jun 01 00:00:00 EDT 2022
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.
Cell death & disease
Li P,Lin Q,Sun S,Yang N,Xia Y,Cao S,Zhang W,Li Q,Guo H,Zhu M,Wang Y,Zheng Z,Li S
Wed Sep 21 00:00:00 EDT 2022
Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity.
Peptides
Cai R,Zhang X,Wang H,Cui T,Halmos G,Sha W,He J,Popovics P,Vidaurre I,Zhang C,Mirsaeidi M,Schally AV
Fri Apr 01 00:00:00 EDT 2022
Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
Drug design, development and therapy
Wang J,Zhang Y,Zhang M,Sun S,Zhong Y,Han L,Xu Y,Wan D,Zhang J,Zhu H
Mon Mar 28 00:00:00 EDT 2022
Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis.
Frontiers in pharmacology
Li W,Yang K,Li B,Wang Y,Liu J,Chen D,Diao Y
Wed Dec 21 00:00:00 EST 2022
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Gut pathogens
Siddiqui NZ,Rehman AU,Yousuf W,Khan AI,Farooqui NA,Zang S,Xin Y,Wang L
Sat Sep 17 00:00:00 EDT 2022
Alda-1, an Aldehyde Dehydrogenase 2 Agonist, Improves Cutaneous Wound Healing by Activating Epidermal Keratinocytes via Akt/GSK-3β/β-Catenin Pathway.
Aesthetic plastic surgery
Zhang SM,Yang Z,Qi FZ
Fri Apr 01 00:00:00 EDT 2022
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Biological research
Li X,Liu D,Chen H,Zeng B,Zhao Q,Zhang Y,Chen Y,Wang J,Xing HR
Sat Oct 01 00:00:00 EDT 2022
Involvement of Rab11 in osteoblastic differentiation: Its up-regulation during the differentiation and by tensile stress.
Biochemical and biophysical research communications
Thant L,Kakihara Y,Kaku M,Kitami M,Kitami K,Mizukoshi M,Maeda T,Saito I,Saeki M
Sat Oct 08 00:00:00 EDT 2022
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Neuroscience letters
Hu S,Shen P,Chen B,Tian SW,You Y
Sun Sep 25 00:00:00 EDT 2022
Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus.
The Journal of clinical investigation
Gao X,Song Y,Wu J,Lu S,Min X,Liu L,Hu L,Zheng M,Du P,Yu Y,Long H,Wu H,Jia S,Yu D,Lu Q,Zhao M
Mon May 02 00:00:00 EDT 2022
Effects of Dietary Indole-3-carboxaldehyde Supplementation on Growth Performance, Intestinal Epithelial Function, and Intestinal Microbial Composition in Weaned Piglets.
Frontiers in nutrition
Zhang R,Huang G,Ren Y,Wang H,Ye Y,Guo J,Wang M,Zhu W,Yu K
Sat Jul 16 00:00:00 EDT 2022
Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.
Journal of medicinal chemistry
Zhao HY,Wang HP,Mao YZ,Zhang H,Xin M,Xi XX,Lei H,Mao S,Li DH,Zhang SQ
Thu Mar 24 00:00:00 EDT 2022
Expression Profile and Localization of SARS-CoV-2 Nonstructural Replicase Proteins in Infected Cells.
Microbiology spectrum
Shi FS,Yu Y,Li YL,Cui L,Zhao Z,Wang M,Wang B,Zhang R,Huang YW
Wed Aug 31 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver
Wang B,Zhang H,Chen YF,Hu LQ,Tian YY,Tong HW,Wang G,Chen C,Yuan P
Tue Nov 01 00:00:00 EDT 2022
The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction.
Bioengineered
Shen S,Wang J,Zhao Q,Hu Q
Tue Mar 01 00:00:00 EST 2022
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
Journal of ethnopharmacology
Du X,Li C,Zhang S,Sun C,Zhang X,Chen C,Wang X,Cheng F,Wang Q
Thu Feb 10 00:00:00 EST 2022
Autophagy Mediates Escherichia Coli-Induced Cellular Inflammatory Injury by Regulating Calcium Mobilization, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress.
International journal of molecular sciences
Liu J,Qiu R,Liu R,Song P,Lin P,Chen H,Zhou D,Wang A,Jin Y
Wed Nov 16 00:00:00 EST 2022
DSF/Cu induces antitumor effect against diffuse large B-cell lymphoma through suppressing NF-κB/BCL6 pathways.
Cancer cell international
Zhu Y,Lei C,Jiang Q,Yu Q,Qiu L
Tue Jul 26 00:00:00 EDT 2022
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Bioengineered
Zhang J,Shang L,Jiang W,Wu W
Tue Mar 01 00:00:00 EST 2022
Anp32e promotes renal interstitial fibrosis by upregulating the expression of fibrosis-related proteins.
International journal of biological sciences
Wei J,Shan Y,Xiao Z,Wen L,Tao Y,Fang X,Luo H,Tang C,Li Y
Mon Oct 24 00:00:00 EDT 2022
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Translational andrology and urology
Zhang B,Zhu Z,Zhang X,Li F,Ding A
Sat Jan 01 00:00:00 EST 2022
Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations.
Zoological research
Ren ZL,Zhang HB,Li L,Yang ZL,Jiang L
Wed May 18 00:00:00 EDT 2022
Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia.
Journal of agricultural and food chemistry
Xu J,Liu J,Mi Y,Zhao T,Mu D,Meng Q,Wang F,Li N,Hou Y
Wed May 18 00:00:00 EDT 2022
Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway.
Cancer medicine
Xie ZQ,Li HX,Hou XJ,Huang MY,Zhu ZM,Wei LX,Tang CX
Tue Nov 01 00:00:00 EDT 2022
In vitro and in silico anti-osteoporosis activities and underlying mechanisms of a fructan, ABW90-1, from Achyranthes bidentate.
Carbohydrate polymers
Li T,Hou X,Huang Y,Wang C,Chen H,Yan C
Sat Jan 15 00:00:00 EST 2022
Eurycomanol alleviates hyperuricemia by promoting uric acid excretion and reducing purine synthesis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Bao R,Chen Q,Li Z,Wang D,Wu Y,Liu M,Zhang Y,Wang T
Tue Feb 01 00:00:00 EST 2022
Long noncoding RNA GAS5 inhibits proliferation and metastasis in papillary thyroid carcinoma through the IFN/STAT1 signaling pathway.
Pathology, research and practice
Xu Y,Lu J,Lou N,Lu W,Xu J,Jiang H,Ye G
Sun May 01 00:00:00 EDT 2022
Silencing of Rab23 by siRNA inhibits ultraviolet B-induced melanogenesis via downregulation of PKA/CREB/MITF.
Experimental dermatology
Wei X,Huang M,Yang Y,Liu Y,Chi S,Li C
Mon Aug 01 00:00:00 EDT 2022
The single-atom iron nanozyme mimicking peroxidase remodels energy metabolism and tumor immune landscape for synergistic chemodynamic therapy and photothermal therapy of triple-negative breast cancer.
Frontiers in bioengineering and biotechnology
Qian X,Shi R,Chen J,Wang Y,Han X,Sun Y,Ling C,Wang G,Xu AW,Pan Y
Sat Nov 19 00:00:00 EST 2022
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Experimental cell research
Lan B,Zhao H,He Y,Zhao Z,Wang N,Gao Y
Tue Nov 15 00:00:00 EST 2022
HMGB2 causes photoreceptor death via down-regulating Nrf2/HO-1 and up-regulating NF-κB/NLRP3 signaling pathways in light-induced retinal degeneration model.
Free radical biology & medicine
Zhang Y,Zhao Z,Zhao X,Xie H,Zhang C,Sun X,Zhang J
Tue Mar 01 00:00:00 EST 2022
RBMS2 Chemosensitizes Breast Cancer Cells to Doxorubicin by Regulating BMF Expression.
International journal of biological sciences
Xu F,Xia T,Xu QT,Zhang X,Huang YZ,Sun X,Shi L,Zhou XJ,Wei JF,Ding Q
Fri Apr 15 00:00:00 EDT 2022
Inhibitory Effects of Parachlorella Beijerinckii Extracts on the Formation of Advanced Glycation End Products and Glycative Stress-Induced Inflammation in an In Vitro Skin Dermis-Like Model.
Evidence-based complementary and alternative medicine : eCAM
Imai Y,Nakashima Y,Kanno T
Fri Nov 18 00:00:00 EST 2022
Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.
Frontiers in molecular biosciences
Song H,Chen S,Zhang T,Huang X,Zhang Q,Li C,Chen C,Chen S,Liu D,Wang J,Tu Y,Wu Y,Liu Y
Sat Mar 19 00:00:00 EDT 2022
The Effects of Hedgehog Signaling Pathway on the Proliferation and Apoptosis of Melanoma Cells.
Journal of oncology
Peng ZP,Huang SF,Li JJ,Tang XK,Wang XY,Li HM
Sat Apr 30 00:00:00 EDT 2022
Sodium Butyrate Attenuated Diabetes-Induced Intestinal Inflammation by Modulating Gut Microbiota.
Evidence-based complementary and alternative medicine : eCAM
Liu L,Chen Y,Wu Q,Shu A,Sun J
Wed Sep 07 00:00:00 EDT 2022
Rosa centifolia petal extract induces endothelium-dependent and endothelium-independent vasorelaxation in rat aorta and prevents accumulation of inflammatory factors in human umbilical vein endothelial cells.
Journal of food biochemistry
Kaneda H,Hori M,Shinomiya H,Nakajima A,Yamazaki S,Sasaki N,Sato T,Kaneda T
Fri Jul 01 00:00:00 EDT 2022
Menadione Potentiates Auranofin-Induced Glioblastoma Cell Death.
International journal of molecular sciences
Szeliga M,Rola R
Sun Dec 11 00:00:00 EST 2022
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
Aging
Lin C,Chen Z,Guo D,Zhou L,Lin S,Li C,Li S,Wang X,Lin B,Ding Y
Tue Jan 04 00:00:00 EST 2022
Dual-fluorescent reporter for live-cell imaging of the ER during DENV infection.
Frontiers in cellular and infection microbiology
Corliss L,Holliday M,Lennemann NJ
Mon Nov 21 00:00:00 EST 2022
Down-Regulation of Double C2 Domain Alpha Promotes the Formation of Hyperplastic Nerve Fibers in Aganglionic Segments of Hirschsprung's Disease.
International journal of molecular sciences
Xiao J,Meng X,Chen K,Wang J,Wu L,Chen Y,Yu X,Feng J,Li Z
Tue Sep 06 00:00:00 EDT 2022
Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin against 3-MCPD induced kidney injury.
Chemico-biological interactions
Zhong Y,Sun D,Yao Y,Liu Q,Guo T,Wang X,Peng X
Tue Mar 01 00:00:00 EST 2022
DNA Methyltransferase Inhibitor 5-AZA-DC Regulates TGFβ1-Mediated Alteration of Neuroglial Cell Functions after Oxidative Stress.
Oxidative medicine and cellular longevity
Zhao XY,Zhang XL
Tue Oct 11 00:00:00 EDT 2022
Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung Adenocarcinoma.
Frontiers in oncology
Yin J,Che G,Jiang K,Zhou Z,Wu L,Xu M,Liu J,Yan S
Mon May 02 00:00:00 EDT 2022
Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3.
Frontiers in immunology
Ma X,Di Q,Li X,Zhao X,Zhang R,Xiao Y,Li X,Wu H,Tang H,Quan J,Wu Z,Xiao W,Chen W
Mon Jul 25 00:00:00 EDT 2022
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Frontiers in pharmacology
Li MT,Liu LL,Zhou Q,Huang LX,Shi YX,Hou JB,Lu HT,Yu B,Chen W,Guo ZY
Mon Jun 26 00:00:00 EDT 2023
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Journal of agricultural and food chemistry
Liu B,Zhang N,Yang J,Sun W,Zhang R,Zheng X,Wang Z,Siebert HC,Han J
Wed Feb 16 00:00:00 EST 2022
Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells.
In vitro cellular & developmental biology. Animal
Miao Y,Wan W,Zhu K,Pan M,Zhao X,Ma B,Wei Q
Tue Mar 01 00:00:00 EST 2022
Reduction of H3K27cr Modification During DNA Damage in Colon Cancer.
Frontiers in oncology
Liao M,Chu W,Sun X,Zheng W,Gao S,Li D,Pei D
Tue Aug 09 00:00:00 EDT 2022
Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway.
Molecular medicine (Cambridge, Mass.)
Li X,Zhou X,Liu X,Li X,Jiang X,Shi B,Wang S
Sun Sep 04 00:00:00 EDT 2022
SREBP2/Rab11s/GLUT1/6 network regulates proliferation and migration of glioblastoma.
Pathology, research and practice
Cheng C,Tu J,Hu Z,Chen Y,Wang Y,Zhang T,Zhang C,Li C,Wang Y,Niu C
Thu Dec 01 00:00:00 EST 2022
miR-153-3p inhibits osteogenic differentiation of BMSCs by down-regulating the expression of RUNX2 in a high glucose environment.
American journal of translational research
Wang Q,Xia Q,Meng M,Li Y,Tang Z,Zeng X,Chen H,Shu J,Xv X,Chen J,Lu J,Wang H,Ye Z,Song B,Dong Q
Sat Nov 19 00:00:00 EST 2022
Cellular PSMB4 Protein Suppresses Influenza A Virus Replication through Targeting NS1 Protein.
Viruses
Yang CH,Hsu CF,Lai XQ,Chan YR,Li HC,Lo SY
Mon Oct 17 00:00:00 EDT 2022
Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.
Cancer letters
Yan R,Dai W,Wu R,Huang H,Shu M
Sat May 28 00:00:00 EDT 2022
The involvement of TRPM2 on the MPP+-induced oxidative neurotoxicity and apoptosis in hippocampal neurons from neonatal mice: protective role of resveratrol.
Neurological research
Yildizhan K,Çinar R,Naziroğlu M
Fri Jul 01 00:00:00 EDT 2022
Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.
Evidence-based complementary and alternative medicine : eCAM
Chen F,Qu F,Jia Y,Wang C,Yu Y,Liao J,Lin M,Chen F,Sun Z
Sat Jul 23 00:00:00 EDT 2022
Interferon-Stimulated Gene 15 Knockout in Mice Impairs IFNα-Mediated Antiviral Activity.
Viruses
Li C,He WF,Li LX,Chen J,Yang GQ,Chang HT,Liu HM
Wed Aug 24 00:00:00 EDT 2022
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Frontiers in oncology
Parisi L,Mockenhaupt C,Rihs S,Mansour F,Katsaros C,Degen M
Sat Dec 03 00:00:00 EST 2022
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Nutrients
Qin S,Geng H,Wang G,Chen L,Xia C,Yao J,Bai Z,Deng L
Thu Nov 24 00:00:00 EST 2022
Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse.
Frontiers in physiology
Guo H,Liu R,He J,Yao W,Zheng W
Sat Jul 16 00:00:00 EDT 2022
Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.
Frontiers in endocrinology
Xing L,Wu S,Shi Y,Yue F,Wei L,Russell R,Zhang D
Tue Aug 16 00:00:00 EDT 2022
Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Cell death & disease
Chen YH,Xu NZ,Hong C,Li WQ,Zhang YQ,Yu XY,Huang YL,Zhou JY
Tue Nov 08 00:00:00 EST 2022
Renoprotective effects of oleanolic acid and its possible mechanisms in rats with diabetic kidney disease.
Biochemical and biophysical research communications
Liu Y,Hu Z,Xing H,Kang L,Chen X,Liu B,Niu K
Sun Dec 25 00:00:00 EST 2022
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H2 S pathway in diabetic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wen X,Xi Y,Zhang Y,Jiao L,Shi S,Bai S,Sun F,Chang G,Wu R,Hao J,Li H
Sat Jan 01 00:00:00 EST 2022
Porcine Enteric Coronavirus PEDV Induces the ROS-ATM and Caspase7-CAD-γH2AX Signaling Pathways to Foster Its Replication.
Viruses
Ming X,Chen H,Yang Y,Zhao P,Sun L,Zhang C,Shin HJ,Lee JS,Jung YS,Qian Y
Mon Aug 15 00:00:00 EDT 2022
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Frontiers in pharmacology
Yuan Y,Hu Q,Liu L,Xie F,Yang L,Li Y,Zhang C,Chen H,Tang J,Shen X
Fri Mar 25 00:00:00 EDT 2022
Pirh2 restricts influenza A virus replication by modulating short-chain ubiquitination of its nucleoprotein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Chen H,Gao X,Zhao S,Bao C,Ming X,Qian Y,Zhou Y,Jung YS
Sat Oct 01 00:00:00 EDT 2022
A critical ETV4/Twist1/Vimentin axis in Ha-RAS-induced aggressive breast cancer.
Cancer gene therapy
Liu W,Gajendran B,Sample KM,Wang C,Hu A,Chen B,Li Y,Zacksenhaus E,Ben-David Y
Tue Nov 01 00:00:00 EDT 2022
Substitution of the SERCA2 Cys674 reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
British journal of pharmacology
Su H,Mei Y,Luo S,Wu H,He Y,Shiraishi Y,Hu P,Cohen RA,Tong X
Sat Oct 01 00:00:00 EDT 2022
Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility by suppressing HIF-1α/BNIP3-mediated autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhu F,Gao J,Zeng F,Lai Y,Ruan X,Deng G
Thu Dec 01 00:00:00 EST 2022
Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice.
PeerJ
Zhu D,Zou W,Cao X,Xu W,Lu Z,Zhu Y,Hu X,Hu J,Zhu Q
Thu Jan 12 00:00:00 EST 2023
MCTS1 promotes laryngeal squamous cell carcinoma cell growth via enhancing LARP7 stability.
Clinical and experimental pharmacology & physiology
Yang M,Ma B,Liu X
Wed Jun 01 00:00:00 EDT 2022
Facilitating Mitophagy via Pink1/Parkin2 Signaling Is Essential for the Neuroprotective Effect of β-Caryophyllene against CIR-Induced Neuronal Injury.
Brain sciences
Rao J,Wu Y,Fan X,Yang S,Jiang L,Dong Z,Chen S
Thu Jun 30 00:00:00 EDT 2022
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Ecotoxicology and environmental safety
Zhou X,Zhang X,Zhou X,Abulimiti G,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Yang J,Song N
Thu Dec 01 00:00:00 EST 2022
LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.
Cell death & disease
Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J
Thu Aug 18 00:00:00 EDT 2022
Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS.
Journal of inflammation research
Yuan Y,Wang W,Zhang Y,Hong Q,Huang W,Li L,Xie Z,Chen Y,Li X,Meng Y
Fri Apr 08 00:00:00 EDT 2022
SorCS3 promotes the internalization of p75NTR to inhibit GBM progression.
Cell death & disease
Zhang Y,Li Y,Fan Y,Zhang X,Tang Z,Qi J,Zhao B,Li F,Chen X,Liang H,Xu H,Li D
Thu Apr 07 00:00:00 EDT 2022
Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2.
Signal transduction and targeted therapy
Xiong X,Chen S,Shen J,You H,Yang H,Yan C,Fang Z,Zhang J,Cai X,Dong X,Kang T,Li W,Zhou P
Wed Apr 06 00:00:00 EDT 2022
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
International journal of molecular medicine
Ding D,Yan J,Feng G,Zhou Y,Ma L,Jin Q
Sat Jan 01 00:00:00 EST 2022
miR-141-3p affects β-catenin signaling and apoptosis by targeting Ubtd2 in rats with anorectal malformations.
Annals of the New York Academy of Sciences
Wang CY,Li SY,Xiao YX,Zhen L,Wei XG,Tang XB,Yuan ZW,Bai YZ
Thu Dec 01 00:00:00 EST 2022
Liensinine Inhibits Cell Growth and Blocks Autophagic Flux in Nonsmall-Cell Lung Cancer.
Journal of oncology
Chang M,Ding S,Dong X,Shang X,Li Y,Xie L,Song X,Song X
Sat Jul 16 00:00:00 EDT 2022
Tooth Loss Induces Memory Impairment and Glial Activation in Young Wild-Type Mice.
Journal of Alzheimer's disease reports
Taslima F,Abdelhamid M,Zhou C,Chen Y,Jung CG,Michikawa M
Wed Dec 21 00:00:00 EST 2022
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Phytotherapy research : PTR
Zhu C,Tian M,Liu N,Ma L,Lan X,Yang J,Du J,Ma H,Li Y,Zheng P,Yu J,Peng X
Thu Sep 01 00:00:00 EDT 2022
Effects of butein on human osteosarcoma cell proliferation, apoptosis, and autophagy through oxidative stress.
Human & experimental toxicology
Zhang P,Zhang J,Quan H,Chen P,Wang J,Liang Y
Wed Mar 02 00:00:00 EST 2022
Nrf2 improves hippocampal synaptic plasticity, learning and memory through the circ-Vps41/miR-26a-5p/CaMKIV regulatory network.
Experimental neurology
Zhang R,Gao Y,Li Y,Geng D,Liang Y,He Q,Wang L,Cui H
Sun May 01 00:00:00 EDT 2022
Genetic Deletion of HLJ1 Does Not Affect Blood Coagulation in Mice.
International journal of molecular sciences
Hsu MC,Luo WJ,Guo BC,Chen CH,Hu PA,Tsai YH,Su KY,Lee TS
Sun Feb 13 00:00:00 EST 2022
Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models.
Viruses
Wu Y,Chen X,Wang L,Zhou X,Liu Y,Ji D,Ren P,Zhou GG,Zhao J
Thu Dec 15 00:00:00 EST 2022
Hypoxia-Induced miR-210 Promotes Endothelial Cell Permeability and Angiogenesis via Exosomes in Pancreatic Ductal Adenocarcinoma.
Biochemistry research international
Wu G,Ding X,Quan G,Xiong J,Li Q,Li Z,Wang Y
Tue Dec 06 00:00:00 EST 2022
CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.
Frontiers in oncology
Dong S,Li S,Wang X,Liang S,Zhang W,Li L,Xu Q,Shi B,Cheng Z,Zhang X,Zhong M,Zhang G,Hu S
Fri Jul 29 00:00:00 EDT 2022
Evaluation of decompressive craniectomy in mice after severe traumatic brain injury.
Frontiers in neurology
Liu Y,Liu X,Chen Z,Wang Y,Li J,Gong J,He A,Zhao M,Yang C,Yang W,Wang Z
Sat Aug 13 00:00:00 EDT 2022
Involvement of hedgehog signaling in all-trans retinoic acid-mediated suppression of colon cancer.
American journal of translational research
Xu Y,Sun H
Wed Oct 19 00:00:00 EDT 2022
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
BMC musculoskeletal disorders
Xu P,Chang J,Ma G,Liao F,Xu T,Wu Y,Yin Z
Sat Nov 26 00:00:00 EST 2022
Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity.
Cell death & disease
Hu G,Chen Y,Yang X,Wang Y,He J,Wang T,Fan Q,Deng L,Tu J,Tan H,Cheng J
Fri Jul 22 00:00:00 EDT 2022
Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model.
Laboratory animal research
Joelsson JP,Asbjarnarson A,Sigurdsson S,Kricker J,Valdimarsdottir B,Thorarinsdottir H,Starradottir E,Gudjonsson T,Ingthorsson S,Karason S
Fri Jul 22 00:00:00 EDT 2022
Reticulon 2 promotes gastric cancer metastasis via activating endoplasmic reticulum Ca2+ efflux-mediated ERK signalling.
Cell death & disease
Song S,Liu B,Zeng X,Wu Y,Chen H,Wu H,Gu J,Gao X,Ruan Y,Wang H
Fri Apr 15 00:00:00 EDT 2022
Silencing CAMK2D Promotes the Proliferation of Spermatogonia in the Testis of Experimental Varicocele Rats.
Evidence-based complementary and alternative medicine : eCAM
Tang S,Yang P,Ding Y,Chen Q,Huang H,Chen X,Zhou H
Fri Aug 18 00:00:00 EDT 2023
Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells.
Mediators of inflammation
Shi J,Hu Z,Zhou Y,Zuo M,Wu H,Jin W,Xie Z
Thu Mar 31 00:00:00 EDT 2022
Osteoclast-Driven Osteogenesis, Bone Remodeling and Biomaterial Resorption: A New Profile of BMP2-CPC-Induced Alveolar Bone Regeneration.
International journal of molecular sciences
Shen H,Zhuang Y,Zhang C,Zhang C,Yuan Y,Yu H,Si J,Shen G
Thu Oct 13 00:00:00 EDT 2022
Nintedanib Inhibits Endothelial Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis via Focal Adhesion Kinase Activity Reduction.
International journal of molecular sciences
Yu WK,Chen WC,Su VY,Shen HC,Wu HH,Chen H,Yang KY
Mon Jul 25 00:00:00 EDT 2022
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Frontiers in microbiology
Wang X,Yan K,Fu M,Liang S,Zhao H,Fu C,Yang L,Song Z,Sun D,Wan C
Tue Jul 19 00:00:00 EDT 2022
Long noncoding RNA H19 mediates neural stem/progenitor cells proliferation, differentiation and apoptosis through the p53 signaling pathway after ischemic stroke.
Biochemical and biophysical research communications
Gan L,Liao S,Tong Y,Li W,Peng W,Deng S
Tue Mar 15 00:00:00 EDT 2022
OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis.
The Journal of investigative dermatology
Huang YZ,Zheng YX,Zhou Y,Xu F,Cui YZ,Chen XY,Wang ZY,Yan BX,Zheng M,Man XY
Sat Oct 01 00:00:00 EDT 2022
Identification of HMGCR as the anticancer target of physapubenolide against melanoma cells by in silico target prediction.
Acta pharmacologica Sinica
Wang HY,Yu P,Chen XS,Wei H,Cao SJ,Zhang M,Zhang Y,Tao YG,Cao DS,Qiu F,Cheng Y
Wed Jun 01 00:00:00 EDT 2022
Neutrophils Promote Tumor Progression in Oral Squamous Cell Carcinoma by Regulating EMT and JAK2/STAT3 Signaling Through Chemerin.
Frontiers in oncology
Hu X,Xiang F,Feng Y,Gao F,Ge S,Wang C,Zhang X,Wang N
Wed Feb 16 00:00:00 EST 2022
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
International journal of oral science
Tian B,Li X,Zhang J,Zhang M,Gan D,Deng D,Sun L,He X,Wu C,Chen F
Mon Sep 05 00:00:00 EDT 2022
Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
Gastroenterology
Zhou Z,Ren Y,Yang J,Liu M,Shi X,Luo W,Fung KM,Xu C,Bronze MS,Zhang Y,Houchen CW,Li M
Tue Nov 01 00:00:00 EDT 2022
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Song C,Nie C,Sun Y,Wang Y,Xue L,Fan M,Qian H,Wang L,Li Y
Sat Jan 01 00:00:00 EST 2022
Irisin attenuates P. gingivalis-suppressed osteogenic/cementogenic differentiation of periodontal ligament cells via p38 signaling pathway.
Biochemical and biophysical research communications
Huang X,Xiao J,Wang X,Cao Z
Sat Aug 27 00:00:00 EDT 2022
The Effects and Mechanisms of the Rapamycin-eluting Stent in Urethral Stricture Prevention in Rabbits.
Balkan medical journal
Zhang T,Zhao W,Ren T,Chen J,Chen Z,Wang Y,Cheng X,Wu J,Yuan C,He T
Mon Mar 14 00:00:00 EDT 2022
Psychosocial stress and cannabinoid drugs affect acetylation of α-tubulin (K40) and gene expression in the prefrontal cortex of adult mice.
PloS one
Tomas-Roig J,Ramasamy S,Zbarsky D,Havemann-Reinecke U,Hoyer-Fender S
Fri Sep 23 00:00:00 EDT 2022
The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats.
International immunopharmacology
Liu X,Yang B,Tan YF,Feng JG,Jia J,Yang CJ,Chen Y,Wang MH,Zhou J
Sat Oct 01 00:00:00 EDT 2022
Retracted Article: LncRNA KCNQ1OT1 Promotes Apoptosis and Oxidative Stress of Human Lens Epithelial Cells through Epigenetic Regulation of WRN.
Current eye research
Jiang S,Jia Y,Gao Z
Wed Jun 01 00:00:00 EDT 2022
Single Treatment of Vitamin D3 Ameliorates LPS-Induced Acute Lung Injury through Changing Lung Rodentibacter abundance.
Molecular nutrition & food research
Jin A,Zhao Y,Yuan Y,Ma S,Chen J,Yang X,Lu S,Sun Q
Tue Feb 01 00:00:00 EST 2022
Bioelectric fields coordinate wound contraction and re-epithelialization process to accelerate wound healing via promoting myofibroblast transformation.
Bioelectrochemistry (Amsterdam, Netherlands)
Yang J,Liu X,Wang W,Chen Y,Liu J,Zhang Z,Wu C,Jiang X,Liang Y,Zhang J
Thu Dec 01 00:00:00 EST 2022
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Gan X,Huang H,Wen J,Liu K,Yang Y,Li X,Fang G,Liu Y,Wang X
Mon Aug 01 00:00:00 EDT 2022
The comprehensive expression and functional analysis of m6A modification "readers" in hepatocellular carcinoma.
Aging
Qin S,Liu G,Jin H,Chen X,He J,Xiao J,Qin Y,Mao Y,Zhao L
Fri Aug 12 00:00:00 EDT 2022
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis.
Cell death & disease
Lv F,He Y,Xu H,Li Y,Han L,Yan L,Lang H,Zhao Y,Zhao Z,Qi Y
Tue Aug 23 00:00:00 EDT 2022
Transient and Prolonged Activation of Wnt Signaling Contribute Oppositely to the Pathogenesis of Asherman's Syndrome.
International journal of molecular sciences
Xue X,Li X,Yao J,Zhang X,Ren X,Xu S
Mon Aug 08 00:00:00 EDT 2022
Identifying potential prognosis markers in hepatocellular carcinoma via integrated bioinformatics analysis and biological experiments.
Frontiers in genetics
Hu X,Zhou J,Zhang Y,Zeng Y,Jie G,Wang S,Yang A,Zhang M
Sat Aug 06 00:00:00 EDT 2022
Exosomal circGSE1 promotes immune escape of hepatocellular carcinoma by inducing the expansion of regulatory T cells.
Cancer science
Huang M,Huang X,Huang N
Wed Jun 01 00:00:00 EDT 2022
Pectin supplementation ameliorates intestinal epithelial barrier function damage by modulating intestinal microbiota in lipopolysaccharide-challenged piglets.
The Journal of nutritional biochemistry
Wen X,Zhong R,Dang G,Xia B,Wu W,Tang S,Tang L,Liu L,Liu Z,Chen L,Zhang H
Tue Nov 01 00:00:00 EDT 2022
Resveratrol pretreatment protects neurons from oxygen-glucose deprivation/reoxygenation and ischemic injury through inhibiting ferroptosis.
Bioscience, biotechnology, and biochemistry
Zhu H,Huang J,Chen Y,Li X,Wen J,Tian M,Ren J,Zhou L,Yang Q
Tue May 24 00:00:00 EDT 2022
Mild hypothermia ameliorates hepatic ischemia reperfusion injury by inducing RBM3 expression.
Apoptosis : an international journal on programmed cell death
Xiao Q,Liu Y,Zhang X,Liu Z,Xiao J,Ye Q,Fu B
Thu Dec 01 00:00:00 EST 2022
Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity.
Experimental gerontology
Li XL,Tao X,Li TC,Zhu ZM,Huang PL,Gong WJ
Tue Nov 01 00:00:00 EDT 2022
Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus.
PloS one
Wen C,Yu Y,Gao C,Qi X,Cardona CJ,Xing Z
Mon Apr 25 00:00:00 EDT 2022
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
Cell death & disease
Peng W,Zhou X,Xu T,Mao Y,Zhang X,Liu H,Liang L,Liu L,Liu L,Xiao Y,Zhang F,Li S,Shi M,Zhou Y,Tang L,Wang Y,Guo B
Mon Mar 21 00:00:00 EDT 2022
Fucoidan ameliorates glucose metabolism by the improvement of intestinal barrier and inflammatory damage in type 2 diabetic rats.
International journal of biological macromolecules
Liu Y,Xu Z,Huang H,Xue Y,Zhang D,Zhang Y,Li W,Li X
Tue Mar 15 00:00:00 EDT 2022
Differential expression pattern, bioinformatics analysis, and validation of circRNA and mRNA in patients with arteriosclerosis.
Frontiers in cardiovascular medicine
Liu Y,Wang K,Li G,Chen Z
Sat Oct 01 00:00:00 EDT 2022
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Food & function
Liu Y,Huang H,Xu Z,Xue Y,Zhang D,Zhang Y,Li W,Li X
Mon Mar 07 00:00:00 EST 2022
TiO2 nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Journal of hazardous materials
Li S,Yan D,Huang C,Yang F,Cao Y
Tue Feb 15 00:00:00 EST 2022
The neural stem cell properties of Pkd2l1+ cerebrospinal fluid-contacting neurons in vivo.
Frontiers in cellular neuroscience
Cao L,Huang MZ,Zhang Q,Luo ZR,Zhang Y,An PJ,Yang LL,Tan W,Wang CQ,Dou XW,Li Q
Wed Sep 28 00:00:00 EDT 2022
Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function.
Bioengineering (Basel, Switzerland)
Li Q,Liu X,Liu W,Zhang Y,Liu W,Wu M,Chen Z,Zhao Y,Zou L
Fri Nov 04 00:00:00 EDT 2022
Integrated multi-omics analysis reveals miR-20a as a regulator for metabolic colorectal cancer.
Heliyon
Song K,Liu C,Zhang J,Yao Y,Xiao H,Yuan R,Li K,Yang J,Zhao W,Zhang Y
Tue Mar 01 00:00:00 EST 2022
O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.
Journal of advanced research
Zhang H,Qi J,Pei J,Zhang M,Shang Y,Li Z,Wang Y,Guo J,Sun K,Fan J,Sui L,Xu Y,Kong L,Kong Y
Tue Mar 01 00:00:00 EST 2022
Effect of Astragalus polysaccharides on the cryopreservation of goat semen.
Theriogenology
Zhang X,Hu ZT,Li Y,Li YX,Xian M,Guo SM,Hu JH
Tue Nov 01 00:00:00 EDT 2022
Dihydroartemisinin represses oral squamous cell carcinoma progression through downregulating mitochondrial calcium uniporter.
Bioengineered
Zheng S,Wu R,Deng Y,Zhang Q
Sat Jan 01 00:00:00 EST 2022
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Journal of oncology
Wu W,Gou H,Xiang B,Geng R,Dong J,Yang X,Chen D,Dai R,Chen L,Liu J
Sat Sep 24 00:00:00 EDT 2022
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Evidence-based complementary and alternative medicine : eCAM
Xu G,Ma T,Zhou C,Zhao F,Peng K,Li B
Sat Jul 16 00:00:00 EDT 2022
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
Redox biology
Ma S,Zhou X,Wang Y,Li Z,Wang Y,Shi J,Guan F
Fri Jul 01 00:00:00 EDT 2022
High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.
International journal of medical sciences
Sun Y,Zhu X,Zhu K,Yu J,Cheng L,Hei M
Thu Dec 15 00:00:00 EST 2022
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
Biology
Yang X,Jiang W,Kong X,Zhou X,Zhu D,Kong L
Thu Sep 22 00:00:00 EDT 2022
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Frontiers in pharmacology
Zhou Z,Liang S,Zhou Z,Liu J,Meng X,Zou F,Yu C,Cai S
Tue Mar 01 00:00:00 EST 2022
Construction, bioinformatics analysis, and validation of competitive endogenous RNA networks in ulcerative colitis.
Frontiers in genetics
Dong L,Zhang R,Huang Q,Shen Y,Li H,Yu S,Wu Q
Wed Sep 07 00:00:00 EDT 2022
Shuangyu Tiaozhi decoction alleviates non-alcoholic fatty liver disease by improving lipid deposition, insulin resistance, and inflammation in vitro and in vivo.
Frontiers in pharmacology
Yin G,Liang H,Sun W,Zhang S,Feng Y,Liang P,Chen S,Liu X,Pan W,Zhang F
Wed Dec 21 00:00:00 EST 2022
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Food & function
Zhang S,Li J,Shi X,Tan X,Si Q
Mon Oct 03 00:00:00 EDT 2022
1H-NMR-based metabolomics reveals the biomarker panel and molecular mechanism of hepatocellular carcinoma progression.
Analytical and bioanalytical chemistry
Wang KX,Du GH,Qin XM,Gao L
Tue Feb 01 00:00:00 EST 2022
The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose.
Chemico-biological interactions
Gao M,Yang Y,Gao Y,Liu T,Guan Q,Zhou T,Shi Y,Hao M,Li Z,Zuo D,Zhang W,Wu Y
Fri Feb 25 00:00:00 EST 2022
Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.
Bioengineered
Zhao J,Pan B,Zhou X,Wu C,Hao F,Zhang J,Liu L
Tue Feb 01 00:00:00 EST 2022
CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a.
Frontiers in pharmacology
Liu H,Lu WL,Hong HQ,Li MJ,Ye MP,Rao QF,Kong JL,Luan SH,Huang Y,Hu QH,Wu FR
Tue Jan 03 00:00:00 EST 2023
Cytomegalovirus-specific neutralizing antibodies effectively prevent uncontrolled infection after allogeneic hematopoietic stem cell transplantation.
iScience
Wang H,Liu H,Zhou L,Wang D,Wang S,Liu Q,Wu Y,Tu M,Sun Z,Zheng X,Fu B,Wang B,Wei H
Fri Oct 21 00:00:00 EDT 2022
Mechanical Stimulation Protects Against Chondrocyte Pyroptosis Through Irisin-Induced Suppression of PI3K/Akt/NF-κB Signal Pathway in Osteoarthritis.
Frontiers in cell and developmental biology
Jia S,Yang Y,Bai Y,Wei Y,Zhang H,Tian Y,Liu J,Bai L
Fri Apr 01 00:00:00 EDT 2022
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
BioMed research international
Liu G,Guan Y,Liu Y,Wang Y,Zhang J,Liu Y,Liu X
Tue Dec 06 00:00:00 EST 2022
Artesunate Suppresses the Growth of Lung Cancer Cells by Downregulating the AKT/Survivin Signaling Pathway.
BioMed research international
Zhang W,Ning N,Huang J
Fri Apr 08 00:00:00 EDT 2022
Activation of RKIP Binding ASC Attenuates Neuronal Pyroptosis and Brain Injury via Caspase-1/GSDMD Signaling Pathway After Intracerebral Hemorrhage in Mice.
Translational stroke research
Gu L,Sun M,Li R,Tao Y,Luo X,Xu J,Wu X,Xie Z
Thu Dec 01 00:00:00 EST 2022
N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.
Cancer letters
Sun Y,Guan Z,Sheng Q,Duan W,Zhao H,Zhou J,Deng Q,Pei X
Thu Mar 31 00:00:00 EDT 2022
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease.
Frontiers in medicine
Wang D,Yin L,Chen R,Tan W,Liang L,Xiang J,Zhang H,Zhou X,Deng H,Guo B,Wang Y
Sat Feb 11 00:00:00 EST 2023
miR-let-7c-3p targeting on Egr-1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages.
Oncology letters
Qi F,Wang X,Zhao S,Wang C,Sun R,Wang H,Du P,Wang J,Wang X,Jiang G
Mon Aug 01 00:00:00 EDT 2022
Beta-naphthoflavone and doxorubicin synergistically enhance apoptosis in human lung cancer cells by inducing doxorubicin accumulation, mitochondrial ROS generation, and JNK pathway signaling.
Biochemical and biophysical research communications
Hoang DH,Song M,Kovale LM,Tran QH,Choe W,Kang I,Kim SS,Ha J
Tue Dec 20 00:00:00 EST 2022
Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation.
Cell reports
Li Y,Li YC,Liu XT,Zhang L,Chen YH,Zhao Q,Gao W,Liu B,Yang H,Li P
Tue Feb 15 00:00:00 EST 2022
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Food & function
Zhong Y,Liu J,Sun D,Guo T,Yao Y,Xia X,Shi C,Peng X
Mon Mar 21 00:00:00 EDT 2022
Verteporfin inhibits the dedifferentiation of tubular epithelial cells via TGF-β1/Smad pathway but induces podocyte loss in diabetic nephropathy.
Life sciences
Qi C,Hu Y,Zeng M,Chen H,Shi J,Jue H,Zhao Z,Liu J,Zhang Z,Xu Y,Wu H
Thu Dec 15 00:00:00 EST 2022
Iron oxide nanoparticles oxidize transformed RAW 264.7 macrophages into foam cells: Impact of pulmonary surfactant component dipalmitoylphosphatidylcholine.
Chemosphere
Li H,Tao X,Song E,Song Y
Mon Aug 01 00:00:00 EDT 2022
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
ChemMedChem
Ye H,Ma Z,Liu L,Zhang T,Han Q,Xiang Z,Xia Y,Ke Y,Guan X,Shi Q,Ataullakhanov FI,Panteleev M
Fri Dec 16 00:00:00 EST 2022
Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
Chemical research in toxicology
Sadahiro Y,Hitora Y,Kimura I,Hitora-Imamura N,Onodera R,Motoyama K,Tsukamoto S
Mon Sep 19 00:00:00 EDT 2022
Serine 727 phosphorylation is necessary to induce the STAT3-mediated transcription of LINC00184 in oesophageal squamous cell carcinoma.
Molecular and cellular biochemistry
Jin C,Qi H,Xu Y,Li S
Wed Jun 01 00:00:00 EDT 2022
Titania-Nanotube-Coated Titanium Substrates Promote Osteogenesis and Suppress Osteoclastogenesis via Integrin ανβ3.
ACS applied bio materials
Kang H,Dong Y,Liu H,Luo C,Song H,Zhu M,Guo Q,Peng R,Li F,Li Y
Mon Dec 19 00:00:00 EST 2022
Cordycepin exhibits anti-fatigue effect via activating TIGAR/SIRT1/PGC-1α signaling pathway.
Biochemical and biophysical research communications
Chai X,Pan M,Wang J,Feng M,Wang Y,Zhang Q,Sun Y
Sat Dec 31 00:00:00 EST 2022
Sodium tanshinone IIA sulfonate enhances the BMP9-BMPR2-Smad1/5/9 signaling pathway in rat pulmonary microvascular endothelial cells and human embryonic stem cell-derived endothelial cells.
Biochemical pharmacology
Wang J,Liu W,Lu W,Luo X,Lin Y,Liu S,Qian J,Zhang C,Chen H,Li Y,Li X,Chen J,Chen Y,Jiang Q,Liu C,Hong C,Wang T,Tang H,Zhong N,Yang J,Yang K,Sun D
Sun May 01 00:00:00 EDT 2022
Molecular imaging and treatment of PSMA-positive prostate cancer with 99mTc radiolabeled aptamer-siRNA chimeras.
Nuclear medicine and biology
Jiao Y,Xu P,Luan S,Wang X,Gao Y,Zhao C,Fu P
Wed Mar 30 00:00:00 EDT 2022
High‑glucose microenvironment promotes perineural invasion of pancreatic cancer via activation of hypoxia inducible factor 1α.
Oncology reports
Zhang L,Zhang W,Zhang X,Min Y,Zhao Y,Wang B,Li W,Mao S,Min W
Fri Apr 01 00:00:00 EDT 2022
Polystyrene micro- and nano-particle coexposure injures fetal thalamus by inducing ROS-mediated cell apoptosis.
Environment international
Yang D,Zhu J,Zhou X,Pan D,Nan S,Yin R,Lei Q,Ma N,Zhu H,Chen J,Han L,Ding M,Ding Y
Mon Aug 01 00:00:00 EDT 2022
Ssc-MiR-21-5p and Ssc-MiR-615 Regulates the Proliferation and Apoptosis of Leydig Cells by Targeting SOX5.
Cells
Tang Q,Zhang Y,Yue L,Ren H,Pan C
Thu Jul 21 00:00:00 EDT 2022
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Frontiers in pharmacology
Li B,Wang HY,Huang JH,Xu WF,Feng XJ,Xiong ZP,Dong YJ,Li LZ,He X,Wu HS,Zhang K,Su J,Yu QX,Jiang NH,Lv GY,Chen SH
Fri Jul 29 00:00:00 EDT 2022
A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2.
Journal of the American Society of Nephrology : JASN
Hada I,Shimizu A,Takematsu H,Nishibori Y,Kimura T,Fukutomi T,Kudo A,Ito-Nitta N,Kiuchi Z,Patrakka J,Mikami N,Leclerc S,Akimoto Y,Hirayama Y,Mori S,Takano T,Yan K
Tue Nov 01 00:00:00 EDT 2022
A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2.
Journal of the American Society of Nephrology : JASN
Hada I,Shimizu A,Takematsu H,Nishibori Y,Kimura T,Fukutomi T,Kudo A,Ito-Nitta N,Kiuchi Z,Patrakka J,Mikami N,Leclerc S,Akimoto Y,Hirayama Y,Mori S,Takano T,Yan K
Tue Nov 01 00:00:00 EDT 2022
GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer.
Cancer letters
Shen Z,Li Z,Liu Y,Li Y,Feng X,Zhan Y,Lin M,Fang C,Fang Y,Deng H
Sat May 28 00:00:00 EDT 2022
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
Journal of food biochemistry
Lu S,Yuan Y,Chen F,Zheng Y,Li C,Cao J,Xia G,Liu Z,Shen X,He Y,Zhou D,Zhu K
Thu Dec 01 00:00:00 EST 2022
Acupuncture Effect Assessment in APP/PS1 Transgenic Mice: On Regulating Learning-Memory Abilities, Gut Microbiota, and Microbial Metabolites.
Computational and mathematical methods in medicine
Yang B,He M,Chen X,Sun M,Pan T,Xu X,Zhang X,Gong Q,Zhao Y,Jin Z,Cheng Z
Tue Apr 19 00:00:00 EDT 2022
Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro.
BMC cancer
Khan MA,Zheng M,Fu J,Tania M,Li J,Fu J
Mon Jun 27 00:00:00 EDT 2022
Wnt3a knockdown promotes collagen type II expression in rat chondrocytes.
Experimental and therapeutic medicine
Shi S,Man Z,Sun S
Mon Aug 01 00:00:00 EDT 2022
Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.
PloS one
Liu L,Fu Q,Li T,Shao K,Zhu X,Cong Y,Zhao X
Tue Mar 01 00:00:00 EST 2022
Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways.
Journal of food biochemistry
Ma Y,Xiang S,Jiang W,Kong L,Tan Z,Liang Z,Yuan Z,Yi J,Zhu L
Fri Jul 01 00:00:00 EDT 2022
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
Frontiers in molecular neuroscience
Guo J,Zhang L,Bu Y,Li W,Hu J,Li J
Fri Nov 18 00:00:00 EST 2022
S100A8 regulates autophagy-dependent ferroptosis in microglia after experimental subarachnoid hemorrhage.
Experimental neurology
Tao Q,Qiu X,Li C,Zhou J,Gu L,Zhang L,Pang J,Zhang L,Yin S,Jiang Y,Peng J
Tue Nov 01 00:00:00 EDT 2022
Delivery of nVEGFi using AAV8 for the treatment of neovascular age-related macular degeneration.
Molecular therapy. Methods & clinical development
She K,Su J,Wang Q,Liu Y,Zhong X,Jin X,Zhao Q,Xiao J,Li R,Deng H,Lu F,Yang Y,Wei Y
Thu Mar 10 00:00:00 EST 2022
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer.
Cancer cell international
Wei J,Zheng X,Li W,Li X,Fu Z
Fri Feb 11 00:00:00 EST 2022
Prenatal hypothyroidism diminished exogenous NO-mediated diastolic effects in fetal rat thoracic aorta smooth muscle via increased oxidative stress.
Reproductive toxicology (Elmsford, N.Y.)
Guo J,Yu X,Liu Y,Lu L,Zhu D,Zhang Y,Li L,Zhang P,Gao Q,Lu X,Sun M
Sat Oct 01 00:00:00 EDT 2022
Adaptation to partial urethral obstruction in healthy aging LOU rats and the role of nerve growth factor signaling pathway in the bladder.
Experimental gerontology
Mossa A,Cammisotto PG,Velasquez-Flores M,Campeau L
Sat Jan 01 00:00:00 EST 2022
A DNA damage nanoamplifier for the chemotherapy of triple-negative breast cancer via DNA damage induction and repair blocking.
International journal of pharmaceutics
Huang Y,Dai X,Guan Z,Liu D,Ren L,Chen M,Zeng Z,Jiang J,Luo Y,He Y,Huang M,Zhao C
Sat Jun 25 00:00:00 EDT 2022
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
The Journal of toxicological sciences
Lyu Y,Ren XK,Guo CC,Li ZF,Zheng JP
Fri Dec 02 00:00:00 EST 2022
Acute hypoxia induced dysregulation of clock-controlled ovary functions.
Frontiers in physiology
Ding M,Lu Y,Huang X,Xing C,Hou S,Wang D,Zhang Y,Wang W,Zhang C,Zhang M,Meng F,Liu K,Liu G,Zhao J,Song L
Wed Jan 11 00:00:00 EST 2023
High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma.
Molecular and cellular probes
Zhang LL,Chang W,He SB,Zhang B,Ma G,Shang PF,Yue ZJ
Sat Oct 01 00:00:00 EDT 2022
Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Fang Y,Zhong T,Yang L,Luo F,Li Q,Wang D,Li Q,Fan Y,Yang X
Wed Jul 20 00:00:00 EDT 2022
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
Cancers
Ke S,Liu Z,Wang Q,Zhai G,Shao H,Yu X,Guo J
Sat Aug 13 00:00:00 EDT 2022
FNDC5 Promotes Adipogenic Differentiation of Primary Preadipocytes in Mashen Pigs.
Genes
Hei W,You Z,An J,Zhao T,Li J,Zhang W,Li M,Yang Y,Gao P,Cao G,Guo X,Cai C,Li B
Wed Dec 28 00:00:00 EST 2022
Long non-coding RNA BBOX1-AS1 exacerbates esophageal squamous cell carcinoma development by regulating HOXB7/β-catenin axis.
Experimental cell research
Sheng J,Zhou M,Wang C,Jia J,Chu J,Ju C,Wan J,He J,He F
Wed Jun 01 00:00:00 EDT 2022
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
Frontiers in pharmacology
Zhong WJ,Ma L,Yang F,Cao J,Tan J,Li B
Tue Nov 08 00:00:00 EST 2022
Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.
Life sciences
Chen Y,Liu H,Zheng Q,Li H,You H,Feng Y,Feng W
Sat Oct 01 00:00:00 EDT 2022
Wheat oligopeptides enhance the intestinal mucosal barrier and alleviate inflammation via the TLR4/Myd88/MAPK signaling pathway in aged mice.
Food & nutrition research
Xian Y,Da P,Chao Y,Hui X,Ligang Y,Shaokang W,Guiju S
Thu Mar 10 00:00:00 EST 2022
Zika virus alters centrosome organization to suppress the innate immune response.
EMBO reports
Kodani A,Knopp KA,Di Lullo E,Retallack H,Kriegstein AR,DeRisi JL,Reiter JF
Mon Sep 05 00:00:00 EDT 2022
Astrocytic p75NTR expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption.
Glia
Qin X,Wang J,Chen S,Liu G,Wu C,Lv Q,He X,Bai X,Huang W,Liao H
Sun May 01 00:00:00 EDT 2022
Effects of Xiao Chengqi Formula on Slow Transit Constipation by Assessing Gut Microbiota and Metabolomics Analysis in vitro and in vivo.
Frontiers in pharmacology
Zhou Q,Zhang D,Zhang H,Wan X,Hu B,Zou Q,Su D,Peng H,Huang D,Ren D
Wed Nov 29 00:00:00 EST 2023
Circular RNA CircSHKBP1 accelerates the proliferation, invasion, angiogenesis, and stem cell-like properties via modulation of microR-766-5p/high mobility group AT-hook 2 axis in laryngeal squamous cell carcinoma.
Bioengineered
Chen F,Zhang H,Wang J
Sun May 01 00:00:00 EDT 2022
Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway.
Food & function
Li H,Zhang M,Wang Y,Gong K,Yan T,Wang D,Meng X,Yang X,Chen Y,Han J,Duan Y,Zhang S
Thu Sep 22 00:00:00 EDT 2022
The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice via mediating the FXR/LXRα pathway.
Food & function
Ma S,Pang X,Tian S,Sun J,Hu Q,Li X,Lu Y
Tue Dec 13 00:00:00 EST 2022
TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma.
BMC cancer
Yu J,Gao G,Wei X,Wang Y
Mon Jul 18 00:00:00 EDT 2022
Silencing LINC00491 Inhibits Pancreatic Cancer Progression through MiR-188-5p-induced Inhibition of ZFP91.
Journal of Cancer
Fang Z,Ruan B,Zhong M,Xiong J,Jiang Y,Song Z
Wed Apr 13 00:00:00 EDT 2022
Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
Cell death & disease
Zhao J,Wang G,Han K,Wang Y,Wang L,Gao J,Zhao S,Wang G,Chen S,Luo A,Wu J,Wang G
Mon Jul 11 00:00:00 EDT 2022
Analysis of the expression and distribution of protein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 in the normal adult mouse brain.
Frontiers in neuroanatomy
Jiang H,Feng Y,He G,Liu Y,Li X
Wed Feb 01 00:00:00 EST 2023
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
Cells
Ju L,Yao M,Lu R,Cao Y,Wang H,Yuan L,Xiao F,Shao J,Cai W,Chen L,Bian Z
Fri Nov 11 00:00:00 EST 2022
GALNT3 protects against phosphate-induced calcification in vascular smooth muscle cells by enhancing active FGF23 and inhibiting the wnt/β-catenin signaling pathway.
Cellular signalling
Guo L,Wang Y,Li S,Zhou L,Li D
Thu Dec 01 00:00:00 EST 2022
mascRNA promotes macrophage apoptosis, inhibits osteoclast differentiation and attenuates disease progression in a murine model of arthritis.
Biochemical and biophysical research communications
Wang X,Sun T,Mao X
Thu Jun 30 00:00:00 EDT 2022
Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet.
Foods (Basel, Switzerland)
Ruan Z,Yu Y,Han P,Zhang L,Hu Z
Thu Aug 18 00:00:00 EDT 2022
RNF2 mediates pulmonary fibroblasts activation and proliferation by regulating mTOR and p16-CDK4-Rb1 signaling pathway.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Pan L,Hu Y,Qian C,Yao Y,Wang S,Shi W,Xu T
Tue Nov 01 00:00:00 EDT 2022
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca2+ Signaling Pathway.
Pharmaceuticals (Basel, Switzerland)
Liu J,Zhang C,Wang J,Huang Y,Shen D,Hu Y,Chu H,Yu X,Zhang L,Ma H
Mon Nov 28 00:00:00 EST 2022
Sphingomyelin-Sequestered Cholesterol Domain Recruits Formin-Binding Protein 17 for Constricting Clathrin-Coated Pits in Influenza Virus Entry.
Journal of virology
Tang B,Sun EZ,Zhang ZL,Liu SL,Liu J,Kusumi A,Hu ZH,Zeng T,Kang YF,Tang HW,Pang DW
Wed Mar 09 00:00:00 EST 2022
Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia.
Brain sciences
Xue T,Wang X,Hu Y,Cheng Y,Li H,Shi Y,Wang L,Yin D,Cui D
Sat Oct 15 00:00:00 EDT 2022
A homozygous PIWIL2 frameshift variant affects the formation and maintenance of human-induced pluripotent stem cell-derived spermatogonial stem cells and causes Sertoli cell-only syndrome.
Stem cell research & therapy
Wang X,Li Z,Qu M,Xiong C,Li H
Sat Sep 24 00:00:00 EDT 2022
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
Cell death discovery
Li C,Zhao M,Zhao M,Chen N,Guo Y,Du Y,Zhang Y,Cao B,Zhan B,Guo C,Li Y,Li Y,Shi Y,Zhu F,Zhang L,Wang Q
Tue Apr 05 00:00:00 EDT 2022
ANKRD37 inhibits trophoblast migration and invasion by regulating the NF-κB pathway in preeclampsia.
The journal of gene medicine
Tan W,Fu H,Zhou X,Duan Y,Yin N,Huang J,Liu X
Sun May 01 00:00:00 EDT 2022
Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways.
Frontiers in immunology
Bai S,Wu Q,Zhu S,Zhang Y,Chen X,Su M,Pan J,Li S,Yue T,Xu L,Xie D,Tian C,Zhao D,Li X,Hou J,Wang L,Fu S,Xue Y,Jiang A,Li D,Xu T,Tian Z,Zhou R,Zhang H,Bai L
Thu Feb 09 00:00:00 EST 2023
Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells.
Cell death discovery
Lv J,Yi Y,Qi Y,Yan C,Jin W,Meng L,Zhang D,Jiang W
Thu Feb 17 00:00:00 EST 2022
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Nature communications
Liu Y,Azizian NG,Sullivan DK,Li Y
Thu Nov 17 00:00:00 EST 2022
Ginsenoside Rg1 Inhibits STAT3 Expression by miR-15b-5p to Attenuate Lung Injury in Mice with Type 2 Diabetes Mellitus-Associated Pulmonary Tuberculosis.
Evidence-based complementary and alternative medicine : eCAM
Ma T,Mao X,Meng X,Wang Q
Wed Oct 19 00:00:00 EDT 2022
Identification of an autophagy-related 12-lncRNA signature and evaluation of NFYC-AS1 as a pro-cancer factor in lung adenocarcinoma.
Frontiers in genetics
Tong F,Xu L,Xu S,Zhang M
Thu Dec 22 00:00:00 EST 2022
1α,25-Dihydroxyvitamin D3 Promotes Angiogenesis After Cerebral Ischemia Injury in Rats by Upregulating the TGF-β/Smad2/3 Signaling Pathway.
Frontiers in cardiovascular medicine
Zhang Y,Mu Y,Ding H,Du B,Zhou M,Li Q,Gong S,Zhang F,Geng D,Wang Y
Tue Apr 05 00:00:00 EDT 2022
Pseudorabies virus kinase UL13 phosphorylates H2AX to foster viral replication.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ming X,Bo Z,Miao Y,Chen H,Bao C,Sun L,Xi R,Zhong Q,Zhao P,Jung YS,Qian Y
Tue Mar 01 00:00:00 EST 2022
1,25(OH)2D3 alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathway.
Placenta
Ma Y,Yang Y,Lv M,Zhang Y,He Q,Zhang Y,Su H,Deng X,Qian Y
Thu Dec 01 00:00:00 EST 2022
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
International journal of molecular sciences
Kong Q,Yan X,Cheng M,Jiang X,Xu L,Shen L,Yu H,Sun L
Fri Mar 18 00:00:00 EDT 2022
Correlation between CDK1 protein and CDK1 mRNA during oocyte maturation in mouse.
The International journal of developmental biology
Sun YT,Zhu AZ
Tue Oct 04 00:00:00 EDT 2022
IMP075 targeting ClpP for colon cancer therapy in vivo and in vitro.
Biochemical pharmacology
Zhang J,Luo B,Sui J,Qiu Z,Huang J,Yang T,Luo Y
Sat Oct 01 00:00:00 EDT 2022
Deoxythymidylate Kinase as a Promising Marker for Predicting Prognosis and Immune Cell Infiltration of Pan-cancer.
Frontiers in molecular biosciences
Lan T,Wang Y,Miao J,Guo H,Wang Z,Wang J,Zhang C,Yang P,Zhang Z,Dunmall LC,Wang Y
Sun Jul 31 00:00:00 EDT 2022
Zoledronic acid generates a spatiotemporal effect to attenuate osteoarthritis by inhibiting potential Wnt5a-associated abnormal subchondral bone resorption.
PloS one
Ding D,Wang L,Yan J,Zhou Y,Feng G,Ma L,Yang Y,Pei X,Jin Q
Mon Aug 01 00:00:00 EDT 2022
Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways.
Frontiers in pharmacology
Lin XL,Shi YN,Cao YL,Tan X,Zeng YL,Luo ST,Li YM,Qin L,Xia BH,Fu RG,Lin LM,Li K,Cao D,Zeng JG,Liao DF
Sat Oct 29 00:00:00 EDT 2022
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Drug design, development and therapy
Xiao S,Zhou Y,Wang Q,Yang D
Thu Jan 05 00:00:00 EST 2023
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Journal of chemical neuroanatomy
Nie BX,Zhao G,Yuan XF,Yu LX,Zhang J,Yuan Y,Liu Y,Hu J,Song E,Zhou YC,Shu J
Sat Jan 01 00:00:00 EST 2022
Dihydrotanshinone I Inhibits the Lung Metastasis of Breast Cancer by Suppressing Neutrophil Extracellular Traps Formation.
International journal of molecular sciences
Zhao H,Liang Y,Sun C,Zhai Y,Li X,Jiang M,Yang R,Li X,Shu Q,Kai G,Han B
Fri Dec 02 00:00:00 EST 2022
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Cells
Qin M,Xin Y,Bian Y,Yang X,Xi T,Xiong J
Thu Jan 13 00:00:00 EST 2022
The effects of angiotensin I-converting enzyme inhibitory peptide VGINYW and the hydrolysate of α-lactalbumin on blood pressure, oxidative stress and gut microbiota of spontaneously hypertensive rats.
Food & function
Xie D,Shen Y,Su E,Du L,Xie J,Wei D
Mon Mar 07 00:00:00 EST 2022
Paclitaxel Induces the Apoptosis of Prostate Cancer Cells via ROS-Mediated HIF-1α Expression.
Molecules (Basel, Switzerland)
Zhang Y,Tang Y,Tang X,Wang Y,Zhang Z,Yang H
Mon Oct 24 00:00:00 EDT 2022
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
BMC medicine
Zhan Y,Zhang Z,Liu Y,Fang Y,Xie Y,Zheng Y,Li G,Liang L,Ding Y
Wed Oct 19 00:00:00 EDT 2022
LncRNA-CCAT1/miR-152-3p is involved in CSE-induced inflammation in HBE cells via regulating ERK signaling pathway.
International immunopharmacology
Zong D,Liu X,Li J,Long Y,Ouyang R,Chen Y
Mon Aug 01 00:00:00 EDT 2022
Identification and Validation of a Prognostic Signature Based on Methylation Profiles and Methylation-Driven Gene DAB2 as a Prognostic Biomarker in Differentiated Thyroid Carcinoma.
Disease markers
Ju G,Zhang L,Guo W,Wang H,Zhang X,Mu Z,Sun Y,Sun D,Diao H,Miao S,Chen Y,Xing T,Liang J,Lin Y
Fri May 26 00:00:00 EDT 2023
Protocatechuic aldehyde prevents ischemic injury by attenuating brain microvascular endothelial cell pyroptosis via lncRNA Xist.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Guo Y,Yang JH,He Y,Zhou HF,Wang Y,Ding ZS,Jin B,Wan HT
Sat Jan 01 00:00:00 EST 2022
Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis.
Journal of nanobiotechnology
Wang M,Zeng F,Ning F,Wang Y,Zhou S,He J,Li C,Wang C,Sun X,Zhang D,Xiao J,Hu P,Reilly S,Xin H,Xu X,Zhang X
Tue Jan 04 00:00:00 EST 2022
Activation of PPARγ Protects Obese Mice from Acute Lung Injury by Inhibiting Endoplasmic Reticulum Stress and Promoting Mitochondrial Biogenesis.
PPAR research
Tang Y,Wei K,Liu L,Ma J,Wu S,Tang W
Tue Oct 11 00:00:00 EDT 2022
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Materials today. Bio
Zhang D,Ren Y,He Y,Chang R,Guo S,Ma S,Guan F,Yao M
Wed Jun 01 00:00:00 EDT 2022
Long noncoding RNA lnc-H2AFV-1 promotes cell growth by regulating aberrant m6A RNA modification in head and neck squamous cell carcinoma.
Cancer science
Chen X,Liu Y,Sun D,Sun R,Wang X,Li M,Song N,Ying J,Guo T,Jiang Y
Wed Jun 01 00:00:00 EDT 2022
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction.
Frontiers in pharmacology
Zhao J,Xu X,Yang X
Fri Nov 18 00:00:00 EST 2022
Resveratrol attenuates methylmercury-induced neurotoxicity by modulating synaptic homeostasis.
Toxicology and applied pharmacology
Wang W,Deng C,Chen F,Zhang L,Hu Y,Lu Q,Zhang A
Fri Apr 01 00:00:00 EDT 2022
Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer.
Bioengineered
Wu W,Zhou S,Liu T,Liang D
Sun May 01 00:00:00 EDT 2022
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Frontiers in immunology
Chen Y,He J,Chen R,Wang Z,Dai Z,Liang X,Wu W,Luo P,Zhang J,Peng Y,Zhang N,Liu Z,Zhang L,Zhang H,Cheng Q
Fri Aug 26 00:00:00 EDT 2022
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
Microbial pathogenesis
Zhang ZW,Ansari AR,Dong L,Niu XY,Yang WJ,Li HZ,Xu FL,Yang KL,Song H
Tue Mar 01 00:00:00 EST 2022
The NDUFV2 gene silencing inhibits the proliferation of two drug-resistant cancer cell lines.
Journal, genetic engineering & biotechnology
Liu L,Wang X,Li Y,Ma C,Shi Y,Li X,Chen J
Tue Apr 26 00:00:00 EDT 2022
The Translational Landscape Revealed the Sequential Treatment Containing ATRA plus PI3K/AKT Inhibitors as an Efficient Strategy for AML Therapy.
Pharmaceutics
Wang K,Ou Z,Deng G,Li S,Su J,Xu Y,Zhou R,Hu W,Chen F
Fri Oct 28 00:00:00 EDT 2022
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Biomaterials
Shi M,Zhang J,Wang Y,Peng C,Hu H,Qiao M,Zhao X,Chen D
Fri Apr 01 00:00:00 EDT 2022
Low Sulfur Amino Acid, High Polyunsaturated Fatty Acid Diet Inhibits Breast Cancer Growth.
International journal of molecular sciences
Turchi R,Tortolici F,Benvenuto M,Punziano C,De Luca A,Rufini S,Faraonio R,Bei R,Lettieri-Barbato D,Aquilano K
Fri Dec 23 00:00:00 EST 2022
Anti-inflammatory effect of Bifidobacterium animalis subsp. lactis A6 on DSS-induced colitis in mice.
Journal of applied microbiology
Wang H,Fan C,Zhao Z,Zhai Z,Hao Y
Thu Sep 01 00:00:00 EDT 2022
The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles.
Journal of virology
Du S,Xu W,Wang Y,Li L,Hao P,Tian M,Wang M,Li T,Wu S,Liu Q,Bai J,Qu X,Jin N,Zhou B,Liao M,Li C
Wed Mar 23 00:00:00 EDT 2022
High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia.
Frontiers in genetics
Ren Z,Huang X,Lv Q,Lei Y,Shi H,Wang F,Wang M
Tue Jan 03 00:00:00 EST 2023
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Cell death and differentiation
Guo Z,Geng M,Huang Y,Han G,Jing R,Lin C,Zhang X,Zhang M,Fan G,Wang F,Yin H
Sat Oct 01 00:00:00 EDT 2022
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.
Molecules (Basel, Switzerland)
Wang YC,Zhang RH,Hu SC,Zhang H,Yang D,Zhang WL,Zhao YL,Cui DB,Li YJ,Pan WD,Liao SG,Zhou M
Thu Jun 23 00:00:00 EDT 2022
Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML.
Cell death & disease
Zhang F,Sun J,Tang X,Liang Y,Jiao Q,Yu B,Dai Z,Yuan X,Li J,Yan J,Zhang Z,Fan S,Wang M,Hu H,Zhang C,Lv XB
Fri Jul 08 00:00:00 EDT 2022
Transcriptome Profiling Analysis Identifies LCP1 as a Contributor for Chidamide Resistance in Gastric Cancer.
Pharmaceutical research
Bao W,Zhu Z,Gao Y,Chen J
Sun May 01 00:00:00 EDT 2022
Tetrahydroxy Stilbene Glucoside Alleviates Ischemic Stroke by Regulating Conformation-Dependent Intracellular Distribution of PKM2 for M2 Macrophage Polarization.
Journal of agricultural and food chemistry
Li M,Lu W,Meng Y,Zhang W,Wang F,Sun L,Xu Y
Wed Dec 14 00:00:00 EST 2022
Phellinus linteus polysaccharides mediates acetaminophen-induced hepatotoxicity via activating AMPK/Nrf2 signaling pathways.
Aging
Zhao L,Zheng L,Li Z,Jin M,Wang Q,Cheng J,Li J,Feng H
Thu Sep 01 00:00:00 EDT 2022
Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low glucose-induced astrocytes based on boolean network.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Gao L,Yang WY,Qi H,Sun CJ,Qin XM,Du GH
Sun May 01 00:00:00 EDT 2022
A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
Nutrients
Zou YY,Chen ZL,Sun CC,Yang D,Zhou ZQ,Xiao Q,Peng XY,Tang CF
Mon May 09 00:00:00 EDT 2022
LncRNA SENCR overexpression attenuated the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection via the miR-206/myocardin axis.
Nutrition, metabolism, and cardiovascular diseases : NMCD
Song Y,Wang T,Mu C,Gui W,Deng Y,Ma R
Wed Jun 01 00:00:00 EDT 2022
Isolation of five different primary cell types from a single sample of human skin.
STAR protocols
Kabacik S,Lowe D,Cohen H,Felton S,Spitzer J,Raj K
Fri Jun 17 00:00:00 EDT 2022
Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy.
Journal of nanobiotechnology
Huang X,Qiu M,Wang T,Li B,Zhang S,Zhang T,Liu P,Wang Q,Qian ZR,Zhu C,Wu M,Zhao J
Tue Feb 22 00:00:00 EST 2022
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
Cell death & disease
Yang Q,Lu Y,Shangguan J,Shu X
Wed Nov 23 00:00:00 EST 2022
Deletion of MTAP Highly Sensitizes Osteosarcoma Cells to Methionine Restriction With Recombinant Methioninase.
Cancer genomics & proteomics
Aoki Y,Tome Y,Han Q,Yamamoto J,Hamada K,Masaki N,Kubota Y,Bouvet M,Nishida K,Hoffman RM
Tue Apr 19 00:00:00 EDT 2022
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Journal of bone oncology
Wang Y,Tang Z,Guo W
Mon Aug 01 00:00:00 EDT 2022
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Microbiology spectrum
Wang W,Jiang S,Xu C,Tang L,Liang Y,Zhao Y,Zhu G
Wed Dec 21 00:00:00 EST 2022
Platycodon grandiflorum root fermentation broth reduces inflammation in a mouse IBD model through the AMPK/NF-κB/NLRP3 pathway.
Food & function
Wang Z,Li C,He X,Xu K,Xue Z,Wang T,Xu Z,Liu X
Mon Apr 04 00:00:00 EDT 2022
Pseudorabies Virus Inhibits Expression of Liver X Receptors to Assist Viral Infection.
Viruses
Wang Y,Li GL,Qi YL,Li LY,Wang LF,Wang CR,Niu XR,Liu TX,Wang J,Yang GY,Zeng L,Chu BB
Thu Mar 03 00:00:00 EST 2022
Analysis of the absorbed constituents and mechanism of liquidambaris fructus extract on hepatocellular carcinoma.
Frontiers in pharmacology
Wang S,Yang XX,Li TJ,Zhao L,Bao YR,Meng XS
Sat Sep 17 00:00:00 EDT 2022
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Frontiers in aging neuroscience
Sun W,Wen M,Liu M,Wang Q,Liu Q,Li L,Siebert HC,Loers G,Zhang R,Zhang N
Thu Dec 22 00:00:00 EST 2022
Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway.
Histochemistry and cell biology
Zhang W,Wang Y
Tue Feb 01 00:00:00 EST 2022
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1.
EMBO reports
Liu X,Chen J,Zhang S,Liu X,Long X,Lan J,Zhou M,Zheng L,Zhou J
Mon Sep 05 00:00:00 EDT 2022
SiRNA-circFARSA-loaded porous silicon nanomaterials for pancreatic cancer treatment via inhibition of CircFARSA expression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yuan H,Huang X,Li Q,Luo C,Lin C,Zhang S,Zhang Y,Yan Z,Du N,Liu Z,Jiang H,Chen B
Tue Mar 01 00:00:00 EST 2022
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
In vitro cellular & developmental biology. Animal
Yang M,Feng J,Lan X,Tang Y,Zhang Y,Zhang H,Wang S
Tue Mar 01 00:00:00 EST 2022
Angiotensin-(1-7) improves diabetes mellitus-induced erectile dysfunction in rats by regulating nitric oxide synthase levels.
Peptides
Xu Y,Zhang F,Li C,Hao H,Hao Y
Sun May 01 00:00:00 EDT 2022
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
Theranostics
Zong X,Gu J,Zhou S,Ding D,Hu Y,Tucker L,Huang Z,Geng D,Gao D
Tue Aug 16 00:00:00 EDT 2022
Channel HCN4 mutation R666Q associated with sporadic arrhythmia decreases channel electrophysiological function and increases protein degradation.
The Journal of biological chemistry
Wang H,Wu T,Huang Z,Huang J,Geng Z,Cui B,Yan Y,Zhang Y,Wang Y
Tue Nov 01 00:00:00 EDT 2022
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.
Autophagy
Feng L,Liang L,Zhang S,Yang J,Yue Y,Zhang X
Tue Feb 01 00:00:00 EST 2022
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway.
Autophagy
Feng L,Liang L,Zhang S,Yang J,Yue Y,Zhang X
Tue Feb 01 00:00:00 EST 2022
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.
Frontiers in pharmacology
Yang L,Zhang Y,Wang Y,Jiang P,Liu F,Feng N
Tue Oct 11 00:00:00 EDT 2022
TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia.
Oxidative medicine and cellular longevity
Zhong Y,Zhang Y,Liu W,Zhao Y,Zou L,Liu X
Tue Jun 28 00:00:00 EDT 2022
LHPP suppresses gastric cancer progression via the PI3K/AKT/mTOR signaling pathway.
Journal of Cancer
Wang D,Li J,Li W
Sat Dec 10 00:00:00 EST 2022
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
Journal of Cancer
Wang J,Zeng Z,Lei S,Han J,Liao S,Zhang J,Wang L,Dong Y,Li H,Chen T
Tue Mar 15 00:00:00 EDT 2022
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Frontiers in oncology
Xie W,Yu J,Yin Y,Zhang X,Zheng X,Wang X
Tue Aug 30 00:00:00 EDT 2022
Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis.
Frontiers in molecular biosciences
Li M,Liu Z,Song J,Wang T,Wang H,Wang Y,Guo J
Sat Mar 19 00:00:00 EDT 2022
Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration.
Journal of orthopaedic translation
Jia H,Lin X,Wang D,Wang J,Shang Q,He X,Wu K,Zhao B,Peng P,Wang H,Wang D,Li P,Yang L,Luo Z,Yang L
Tue Mar 01 00:00:00 EST 2022
Hsa_circ_0008234 facilitates proliferation of cutaneous squamous cell carcinoma through targeting miR-127-5p to regulate ADCY7.
Archives of dermatological research
Cai L,Wang Y,Wu J,Wu G
Mon Aug 01 00:00:00 EDT 2022
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy.
Acta histochemica
Wu H,Li G,Chen W,Luo W,Yang Z,You Z,Zou Y
Sat Jan 01 00:00:00 EST 2022
Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy.
ACS nano
Jin J,Yuan P,Yu W,Lin J,Xu A,Xu X,Lou J,Yu T,Qian C,Liu B,Song J,Li L,Piao Y,Xie T,Shen Y,Tao H,Tang J
Tue Jul 26 00:00:00 EDT 2022
Exosomal circRELL1 serves as a miR-637 sponge to modulate gastric cancer progression via regulating autophagy activation.
Cell death & disease
Sang H,Zhang W,Peng L,Wei S,Zhu X,Huang K,Yang J,Chen M,Dang Y,Zhang G
Thu Jan 13 00:00:00 EST 2022
Heat stress-induced mucosal barrier dysfunction is potentially associated with gut microbiota dysbiosis in pigs.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
Xia B,Wu W,Fang W,Wen X,Xie J,Zhang H
Tue Mar 01 00:00:00 EST 2022
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.
Nature communications
Lei X,Lin H,Wang J,Ou Z,Ruan Y,Sadagopan A,Chen W,Xie S,Chen B,Li Q,Wang J,Lin H,Zhu X,Yuan X,Tian T,Lv X,Fu S,Zhu X,Zhou J,Pan G,Xia X,Tannous BA,Ferrone S,Fan S,Li J
Wed Jul 06 00:00:00 EDT 2022
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Oxidative medicine and cellular longevity
Luo M,Hu Y,Lv D,Xie L,Yang S,Zuo D,Xue Y,He A
Wed Aug 03 00:00:00 EDT 2022
Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress.
PeerJ
Zhou X,Huang N,Hou X,Zhu L,Xie Y,Ba Z,Luo Y
Fri Jan 13 00:00:00 EST 2023
KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration.
Cancer management and research
Chen X,Wang P,Ou T,Li J
Sun May 01 00:00:00 EDT 2022
The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway.
Cells
Wan Z,Yang H,Chen P,Wang Z,Cai Y,Yao X,Wang F,Zhang Y
Mon Mar 14 00:00:00 EDT 2022
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Food & function
Liu Z,Liu R,Wang R,Dai J,Chen H,Wang J,Li X
Mon Oct 03 00:00:00 EDT 2022
Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK.
Neurochemical research
Sun X,Li X,Zhou Y,Wang Y,Liu X
Sat Oct 01 00:00:00 EDT 2022
Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry.
BMC pulmonary medicine
Shi F,Wu J,Jia Q,Li K,Li W,Shi Y,Wang Y,Wu S
Fri Oct 07 00:00:00 EDT 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 EDT 2022
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model.
International immunopharmacology
Xiao S,Zhong N,Yang Q,Li A,Tong W,Zhang Y,Yao G,Wang S,Liu J,Liu Z
Sat Oct 01 00:00:00 EDT 2022
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Journal of nanobiotechnology
Jin Y,Zhang Q,Qin X,Liu Z,Li Z,Zhong X,Xia L,He J,Fang B
Thu Nov 03 00:00:00 EDT 2022
Klotho alleviates NLRP3 inflammasome-mediated neuroinflammation in a temporal lobe epilepsy rat model by activating the Nrf2 signaling pathway.
Epilepsy & behavior : E&B
Xiang T,Luo X,Ye L,Huang H,Wu Y
Tue Mar 01 00:00:00 EST 2022
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
Frontiers in aging neuroscience
Cao X,Chen Y,Sang X,Xu S,Xie Z,Zhu Z,Wang P,Bi J,Xu L
Tue Nov 22 00:00:00 EST 2022
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Materials today. Bio
Cui L,Li J,Guan S,Zhang K,Zhang K,Li J
Tue Mar 01 00:00:00 EST 2022
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
Frontiers in oncology
Hu S,Ge M,Zhang S,Jiang M,Hu K,Gao L
Sat May 07 00:00:00 EDT 2022
FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation.
Scientific reports
Czerny CC,Borschel A,Cai M,Otto M,Hoyer-Fender S
Mon Dec 12 00:00:00 EST 2022
Melatonin prevents cyclophosphamide-induced primordial follicle loss by inhibiting ovarian granulosa cell apoptosis and maintaining AMH expression.
Frontiers in endocrinology
Feng J,Ma WW,Li HX,Pei XY,Deng SL,Jia H,Ma WZ
Tue Aug 23 00:00:00 EDT 2022
Zinc Alleviates Arsenic-Induced Inflammation and Apoptosis in the Head Kidney of Common Carp by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress.
Biological trace element research
Xing P,Zhang Y,Chi Q,Li S
Sun May 01 00:00:00 EDT 2022
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Translational psychiatry
Wang L,Chen J,Hu Y,Liao A,Zheng W,Wang X,Lan J,Shen J,Wang S,Yang F,Wang Y,Li Y,Chen D
Tue Mar 22 00:00:00 EDT 2022
Enhancement of the functionality of attenuating acute lung injury by a microemulsion formulation with volatile oil of Angelicae Sinensis Radix and Ligusticum Chuanxiong Rhizoma encapsulated.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang L,Yan Q,Zhang W,Li X,Zhang X,Du S,Hua X,Lin J,Shu G,Peng G,Tan Z,Fu H
Thu Dec 01 00:00:00 EST 2022
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca2+/Endoplasmic Reticulum Stress Signaling Pathway.
Toxins
Wu D,Yang C,Yang M,Wu Y,Mao Y,Zhou X,Wang J,Yuan Z,Wu J
Wed Apr 06 00:00:00 EDT 2022
β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells.
Frontiers in pharmacology
Jalal S,Zhang T,Deng J,Wang J,Xu T,Zhang T,Zhai C,Yuan R,Teng H,Huang L
Tue Aug 30 00:00:00 EDT 2022
Old targets, new strategy: Apigenin-7-O-β-d-(-6″-p-coumaroyl)-glucopyranoside prevents endothelial ferroptosis and alleviates intestinal ischemia-reperfusion injury through HO-1 and MAO-B inhibition.
Free radical biology & medicine
Feng YD,Ye W,Tian W,Meng JR,Zhang M,Sun Y,Zhang HN,Wang SJ,Wu KH,Liu CX,Liu SY,Cao W,Li XQ
Sun May 01 00:00:00 EDT 2022
Global Phosphoproteomics Unveils Kinase-Regulated Networks in Systemic Lupus Erythematosus.
Molecular & cellular proteomics : MCP
Meng S,Li T,Wang T,Li D,Chen J,Li H,Cai W,Zeng Z,Liu D,Tang D,Hong X,Dai Y
Thu Dec 01 00:00:00 EST 2022
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles.
Heliyon
Wu MY,Shi XC,Shan J,Wang R,Wang Y,Li J,Tian DN,Xu HM
Tue Nov 01 00:00:00 EDT 2022
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Inflammation
Wan Q,Zhang L,Zhou Q,Han Y,Li Z,Li B
Wed Jun 01 00:00:00 EDT 2022
Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R-/-) Mice.
BioMed research international
Li W,Zhang H,Zhang L,Zhang T,Ding H
Tue Jul 19 00:00:00 EDT 2022
Geniposide attenuates spermatogenic dysfunction via inhibiting endoplasmic reticulum stress in male mice.
Chemico-biological interactions
Chi YN,Ye RJ,Yang JM,Hai DM,Liu N,Ren JW,Du J,Lan XB,Yu JQ,Ma L
Sat Oct 01 00:00:00 EDT 2022
Intracameral Injection of AAV-DJ.COMP-ANG1 Reduces the IOP of Mice by Reshaping the Trabecular Outflow Pathway.
Investigative ophthalmology & visual science
Qiao Y,Sun Z,Tan C,Lai J,Sun X,Chen J
Thu Dec 01 00:00:00 EST 2022
Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis.
Frontiers in pharmacology
Zhu J,Chen H,Le Y,Guo J,Liu Z,Dou X,Lu D
Sat Nov 26 00:00:00 EST 2022
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Molecular therapy oncolytics
Jiang Q,Wang Z,Qi Q,Li J,Xin Y,Qiu J
Thu Mar 17 00:00:00 EDT 2022
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
Drug design, development and therapy
Zuo Q,Zhang G,He L,Ma S,Ma H,Zhai J,Wang Z,Zhang T,Wang Y,Guo Y
Wed Dec 14 00:00:00 EST 2022
Conditional knockout of ASK1 in microglia/macrophages attenuates epileptic seizures and long-term neurobehavioural comorbidities by modulating the inflammatory responses of microglia/macrophages.
Journal of neuroinflammation
Zhang Y,Wang Z,Wang R,Xia L,Cai Y,Tong F,Gao Y,Ding J,Wang X
Mon Aug 08 00:00:00 EDT 2022
Self-construction of actin networks through phase separation-induced abLIM1 condensates.
Proceedings of the National Academy of Sciences of the United States of America
Yang S,Liu C,Guo Y,Li G,Li D,Yan X,Zhu X
Tue Jul 19 00:00:00 EDT 2022
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
Frontiers in pharmacology
Li F,Wang Y,Tian J,Zhou Z,Yin W,Qin X,Wang H,Zeng T,Li A,Jiang J
Wed Dec 21 00:00:00 EST 2022
Probiotic-fermented Pueraria lobata (Willd.) Ohwi alleviates alcoholic liver injury by enhancing antioxidant defense and modulating gut microbiota.
Journal of the science of food and agriculture
Zhao W,Peng D,Li W,Chen S,Liu B,Huang P,Wu J,Du B,Li P
Thu Dec 01 00:00:00 EST 2022
Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model.
Oxidative medicine and cellular longevity
Ma L,Hao W,Feng WB,Cao LC,Qin LN,Wang Y,Liu MH,Wang NZ,Gao F,Guo JM,Du H,Yan HL
Fri Oct 07 00:00:00 EDT 2022
FTO-dependent N(6)-Methyladenosine regulates the progression of endometriosis via the ATG5/PKM2 Axis.
Cellular signalling
Wang H,Liang Z,Gou Y,Li Z,Cao Y,Jiao N,Tan J,Yu Y,Zhang Z
Sat Oct 01 00:00:00 EDT 2022
Altered gene expression in human brain microvascular endothelial cells in response to the infection of influenza H1N1 virus.
Animal diseases
Higazy D,Lin X,Xie T,Wang K,Gao X,Cui M
Wed Nov 09 00:00:00 EST 2022
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Journal of ethnopharmacology
Jiang Y,Li H,Huang P,Li S,Li B,Huo L,Zhong J,Pan Z,Li Y,Xia X
Tue Mar 01 00:00:00 EST 2022
RNA-seq transcriptome profiling of liver regeneration in mice identifies the miR-34b-5p/phosphoinositide-dependent protein kinase 1 axis as a potential target for hepatocyte proliferation.
Biochemical and biophysical research communications
Lei X,Dai X,Wang Q,Long R,Xiang Z,Li H,Long Z,Zhang C,Zhu Z
Sun Oct 30 00:00:00 EDT 2022
Exposure to melamine cyanuric acid in adult mice caused motor activity and skeletal muscle energy metabolism disorder.
Physiology & behavior
Wang S,Zuo X,Xu B,Yu Q,An Z,Feng D,Feng X
Thu Dec 01 00:00:00 EST 2022
Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation.
Journal of extracellular vesicles
You B,Pan S,Gu M,Zhang K,Xia T,Zhang S,Chen W,Xie H,Fan Y,Yao H,Cheng T,Zhang P,Liu D,You Y
Sun May 01 00:00:00 EDT 2022
A positive feedback loop of the TAZ/β-catenin axis promotes Helicobacter pylori-associated gastric carcinogenesis.
Frontiers in microbiology
Xu X,Shu C,Wu X,Ouyang Y,Cheng H,Zhou Y,Wang H,He C,Xie C,He X,Hong J,Lu N,Ge Z,Zhu Y,Li N
Wed Jan 11 00:00:00 EST 2023
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H2O2-induced BV-2 microglial cells injury.
Bioorganic chemistry
Wang Y,Zhu M,Liang J,Zhang N,Sun D,Li H,Chen L
Tue Nov 01 00:00:00 EDT 2022
Transmissible Gastroenteritis Virus Nucleocapsid Protein Interacts with Na+/H+ Exchanger 3 To Reduce Na+/H+ Exchanger Activity and Promote Piglet Diarrhea.
Journal of virology
Niu Z,Xu S,Zhang Y,Kan Z,Zhang J,Liu X,Zhang S,Zou H,Song Z
Wed Nov 23 00:00:00 EST 2022
Qingfei oral liquid alleviates RSV-induced lung inflammation by promoting fatty-acid-dependent M1/M2 macrophage polarization via the Akt signaling pathway.
Journal of ethnopharmacology
An L,Lu M,Xu W,Chen H,Feng L,Xie T,Shan J,Wang S,Lin L
Tue Nov 15 00:00:00 EST 2022
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang J,Zhang L,Cao H,Shi X,Zhang X,Gao Z,Ikeda K,Yan T,Jia Y,Xu F
Sun May 01 00:00:00 EDT 2022
Phosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice.
Journal of cellular and molecular medicine
Bai Y,Li L,Dong B,Ma W,Chen H,Yu Y
Tue Nov 01 00:00:00 EDT 2022
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
International journal of biological sciences
Dou Z,Qiu C,Zhang X,Yao S,Zhao C,Wang Z,Chu R,Chen J,Chen Z,Li R,Wang K,Liu P,Liu C,Song K,Kong B
Fri Apr 15 00:00:00 EDT 2022
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Frontiers in nutrition
Rehman AU,Siddiqui NZ,Farooqui NA,Alam G,Gul A,Ahmad B,Asim M,Khan AI,Xin Y,Zexu W,Song Ju H,Xin W,Lei S,Wang L
Tue Oct 25 00:00:00 EDT 2022
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Biomedicines
Xu L,Wang J,Liu B,Fu J,Zhao Y,Yu S,Shen L,Yan X,Su J
Thu Feb 03 00:00:00 EST 2022
Inhibition of Metastatic Hepatocarcinoma by Combined Chemotherapy with Silencing VEGF/VEGFR2 Genes through a GalNAc-Modified Integrated Therapeutic System.
Molecules (Basel, Switzerland)
Li X,Wang X,Liu N,Wang Q,Hu J
Thu Mar 24 00:00:00 EDT 2022
Effects of bamboo leaf extract intervention on the growth performance, antioxidant capacity, and hepatic apoptosis in suckling piglets.
Journal of animal science
Yu G,Ji S,Yun Y,Cheng K,Zhang H,Jia P,Wang T,Zhang L
Fri Jul 01 00:00:00 EDT 2022
SIRT3-AMPK signaling pathway as a protective target in endothelial dysfunction of early sepsis.
International immunopharmacology
Yu H,Liu Q,Chen G,Huang L,Luo M,Lv D,Luo S
Sun May 01 00:00:00 EDT 2022
Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
ACS applied materials & interfaces
Guo W,Gao H,Li H,Ge S,Zhang F,Wang L,Shi H,Han A
Wed Jul 20 00:00:00 EDT 2022
An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.
Odontology
Giri S,Takada A,Paudel D,Yoshida K,Furukawa M,Kuramitsu Y,Matsushita K,Abiko Y,Furuichi Y
Sat Jan 01 00:00:00 EST 2022
Gliko BMSC: A potential strategy of treatment for renal fibrosis.
Regenerative therapy
Shi L,Gao X,Bi Y,Li M,Sun H,Tian X,Bi W
Wed Jun 01 00:00:00 EDT 2022
A specific EMC subunit supports Dengue virus infection by promoting virus membrane fusion essential for cytosolic genome delivery.
PLoS pathogens
Bagchi P,Speckhart K,Kennedy A,Tai AW,Tsai B
Fri Jul 01 00:00:00 EDT 2022
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Investigative ophthalmology & visual science
Zhao C,Liu Y,Meng J,Wang X,Liu X,Li W,Zhou Q,Xiang J,Li N,Hou S
Fri Jul 08 00:00:00 EDT 2022
Pyroptosis participates in PM2.5-induced air-blood barrier dysfunction.
Environmental science and pollution research international
Jia R,Wei M,Zhang X,Du R,Sun W,Wang L,Song L
Mon Aug 01 00:00:00 EDT 2022
FLI1 accelerates leukemogenesis through transcriptional regulation of pyruvate kinase-L/R and other glycolytic genes.
Medical oncology (Northwood, London, England)
Sheng D,Chen B,Wang C,Xiao X,Hu A,Liu W,Kuang Y,Sample KM,Zacksenhaus E,Gajendran B,Pan W,Ben-David Y
Sat Dec 31 00:00:00 EST 2022
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
The Journal of surgical research
Yang G,Cao Y,Wang P,Mei L,Chen J,Lu W
Sun May 01 00:00:00 EDT 2022
PM2.5 induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
Immunobiology
Ren F,Xu J,Zhang J,Xu X,Huang L,Sun W,Li R,Li F
Sun May 01 00:00:00 EDT 2022
DL-3-n-butylphthalide imparts neuroprotection via Nrf2/SIRT3 pathway in a mouse model of vascular dementia.
Brain research
Gao L,Guo X,Liu S,Sun Q,Qin X,Lv P,Hu M,Xu J,Dong Y
Tue Mar 15 00:00:00 EDT 2022
D-tagatose protects against oleic acid-induced acute respiratory distress syndrome in rats by activating PTEN/PI3K/AKT pathway.
Frontiers in immunology
Huang J,Wang B,Tao S,Hu Y,Wang N,Zhang Q,Wang C,Chen C,Gao B,Cheng X,Li Y
Tue Oct 04 00:00:00 EDT 2022
IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING.
Journal of immunology research
Zeng X,Li X,Zhang Y,Cao C,Zhou Q
Tue Jun 14 00:00:00 EDT 2022
The BDNF-TrkB-CREB Signalling Pathway Is Involved in Bisphenol S-Induced Neurotoxicity in Male Mice by Regulating Methylation.
Toxics
Li YZ,Wu ZY,Zhu BQ,Wang YX,Kan YQ,Zeng HC
Sat Jul 23 00:00:00 EDT 2022
HIF-1α inhibition attenuates severity of Achilles tendinopathy by blocking NF-κB and MAPK pathways.
International immunopharmacology
Jiao X,Zhang Y,Li W,Zhou X,Chu W,Li Y,Wang Z,Sun X,Xu C,Gan Y
Sun May 01 00:00:00 EDT 2022
Hypoxia-Inducible Factor 1α Stability Modified by Glutaredoxin-1 in Necrotizing Enterocolitis.
The Journal of surgical research
Zhang Y,Zhang X,Tian B,Deng Q,Guo C
Thu Dec 01 00:00:00 EST 2022
The Role of Apoptosis and Autophagy in the Hypothalamic-Pituitary-Adrenal (HPA) Axis after Traumatic Brain Injury (TBI).
International journal of molecular sciences
Taheri S,Karaca Z,Mehmetbeyoglu E,Hamurcu Z,Yilmaz Z,Dal F,Çınar V,Ulutabanca H,Tanriverdi F,Unluhizarci K,Rassoulzadegan M,Kelestimur F
Sat Dec 10 00:00:00 EST 2022
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
PeerJ
Peng X,Yang R,Peng W,Zhao Z,Tu G,He B,Cai Q,Shi S,Yin W,Yu F,Tao Y,Wang X
Tue Dec 27 00:00:00 EST 2022
The underlying rationality of Chinese medicine herb pair Coptis chinensis and Dolomiaea souliei: From the perspective of metabolomics and intestinal function.
Journal of ethnopharmacology
Wang T,Zhang C,Li H,Zhou R,Ye X,Yang Y,He K
Tue May 10 00:00:00 EDT 2022
Arachidonic Acid in Follicular Fluid of PCOS Induces Oxidative Stress in a Human Ovarian Granulosa Tumor Cell Line (KGN) and Upregulates GDF15 Expression as a Response.
Frontiers in endocrinology
Ma Y,Zheng L,Wang Y,Gao Y,Xu Y
Thu Jun 02 00:00:00 EDT 2022
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Frontiers in oncology
Aoki Y,Han Q,Tome Y,Yamamoto J,Kubota Y,Masaki N,Obara K,Hamada K,Wang JD,Inubushi S,Bouvet M,Clarke SG,Nishida K,Hoffman RM
Tue Nov 22 00:00:00 EST 2022
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
Journal of molecular histology
He W,Zhou X,Wu Q,Zhou L,Zhang Z,Zhang R,Deng C,Zhang X
Fri Apr 01 00:00:00 EDT 2022
Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats.
Neurochemical research
Yin C,Zhang Q,Zhao J,Li Y,Yu J,Li W,Wang Q
Fri Apr 01 00:00:00 EDT 2022
Immobilization of peroxisome proliferator-activated receptor gamma and the application in screening modulators of the receptor from herbal medicine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Hou Z,Jin Y,Li Y,Fan H,Xiao C,Li Q,Zhang Y
Tue Feb 01 00:00:00 EST 2022
α1 -Adrenoceptors activate the NLRP3 inflammasome through downregulation of Kir2.1 in cardiac inflammation.
Experimental physiology
Chen L,Wang W,Peng X,Liu L,Zhang A,Li X,Ma K,Wang L
Wed Jun 01 00:00:00 EDT 2022
POLD2 is activated by E2F1 to promote triple-negative breast cancer proliferation.
Frontiers in oncology
Zhang Z
Tue Sep 20 00:00:00 EDT 2022
The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.
Frontiers in molecular neuroscience
Zhong F,Gan Y,Song J,Zhang W,Yuan S,Qin Z,Wu J,Lü Y,Yu W
Wed Jan 11 00:00:00 EST 2023
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A.
The Analyst
Zhang F,Shao C,Wu Y,Zhao W,Jing X,Fang C,Huang Q
Mon Nov 07 00:00:00 EST 2022
Improvement of tube formation model of cell: Application for acute hypoxia in in vitro study of angiogenesis.
Microvascular research
Li F,Gou X,Xu D,Han D,Hou K,Fang W,Li Y
Tue Mar 01 00:00:00 EST 2022
Improvement of tube formation model of cell: Application for acute hypoxia in in vitro study of angiogenesis.
Microvascular research
Li F,Gou X,Xu D,Han D,Hou K,Fang W,Li Y
Tue Mar 01 00:00:00 EST 2022
Improvement of tube formation model of cell: Application for acute hypoxia in in vitro study of angiogenesis.
Microvascular research
Li F,Gou X,Xu D,Han D,Hou K,Fang W,Li Y
Tue Mar 01 00:00:00 EST 2022
Improvement of tube formation model of cell: Application for acute hypoxia in in vitro study of angiogenesis.
Microvascular research
Li F,Gou X,Xu D,Han D,Hou K,Fang W,Li Y
Tue Mar 01 00:00:00 EST 2022
Effect and mechanism of TFEB on pyroptosis in HK-2 cells induced by high glucose.
Biochemical and biophysical research communications
Han N,Wang Z,Luo H,Chi Y,Zhang T,Wang B,Li Y
Sat Jun 25 00:00:00 EDT 2022
Dexamethasone Alleviates Myocardial Injury in a Rat Model of Acute Myocardial Infarction Supported by Venoarterial Extracorporeal Membrane Oxygenation.
Frontiers in public health
Cheng X,Zhang R,Wei S,Huang J,Zhai K,Li Y,Gao B
Mon Aug 08 00:00:00 EDT 2022
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
International journal of molecular sciences
Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J,Zou Y
Thu Apr 28 00:00:00 EDT 2022
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Xiong Y,Li B,Li J,Jin E,He S
Mon Aug 01 00:00:00 EDT 2022
Decreased tubulin-binding cofactor B was involved in the formation disorder of nascent astrocyte processes by regulating microtubule plus-end growth through binding with end-binding proteins 1 and 3 after chronic alcohol exposure.
Frontiers in cellular neuroscience
Zheng Y,Yang M,Chen X,Zhang G,Wan S,Zhang B,Huo J,Liu H
Fri Nov 18 00:00:00 EST 2022
1,25-D3 attenuates cerebral ischemia injury by regulating mitochondrial metabolism via the AMPK/AKT/GSK3β pathway.
Frontiers in aging neuroscience
Li Y,Li X,Xu S,Zhao Y,Pang M,Zhang X,Wang X,Wang Y
Fri Nov 04 00:00:00 EDT 2022
LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p.
Molecular neurobiology
Li S,Zhang L,Lin J,Su A,Liu X,Zhang J,Xian X,Hu Y,Li W,Sun S,Zhang M
Fri Jul 01 00:00:00 EDT 2022
Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.
Diabetes & vascular disease research
Liu Y,Xiang H,Xiong W,Ouyang J,Liu H,Zhao S,Xiao J,Li J,Shu Z,Wang X,Liu H,Zhang J,Fan J,Li Y,Chen S,Lu H
Tue May 17 00:00:00 EDT 2022
Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's disease.
Clinical and experimental pharmacology & physiology
Jiang W,Zou W,Hu M,Tian Q,Xiao F,Li M,Zhang P,Chen YJ,Jiang JM
Sat Jan 01 00:00:00 EST 2022
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Journal of cancer research and therapeutics
Zhang Y,Chen G,Yan Z,Wang L,Wang D
Thu Sep 01 00:00:00 EDT 2022
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Journal of cancer research and therapeutics
Zhang Y,Chen G,Yan Z,Wang L,Wang D
Thu Sep 01 00:00:00 EDT 2022
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Journal of cancer research and therapeutics
Zhang Y,Chen G,Yan Z,Wang L,Wang D
Thu Sep 01 00:00:00 EDT 2022
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Journal of cancer research and therapeutics
Zhang Y,Chen G,Yan Z,Wang L,Wang D
Thu Sep 01 00:00:00 EDT 2022
Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker.
Disease markers
Liu D,Wang X,Liu Y,Li C,Zhang Z,Lv P
Tue Jan 03 00:00:00 EST 2023
Cyclosporin A up-regulated thromboxane A2 receptor through activation of MAPK and NF-κB pathways in rat mesenteric artery.
European journal of pharmacology
Wang C,Han L,Wang T,Wang Y,Liu J,Wang B,Xu CB
Tue Jul 05 00:00:00 EDT 2022
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
Microbiome
Xia B,Zhong R,Wu W,Luo C,Meng Q,Gao Q,Zhao Y,Chen L,Zhang S,Zhao X,Zhang H
Wed Aug 31 00:00:00 EDT 2022
The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism.
Cancers
Zhan X,Qiu R,He Y,Zhao Z,Huang M,Liu Q,Zhi F,Long W
Fri Nov 25 00:00:00 EST 2022
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
International journal of molecular sciences
Lei L,Chen M,Wang C,Jiang X,Li Y,Wang W,Li S,Zhao L,Sheng R,Han J,Zhang Y,Chen Y,Yan B,Wu Y,Yu L,Si S,Xu Y
Thu Nov 03 00:00:00 EDT 2022
Influenza virus NS1 interacts with 14-3-3ε to antagonize the production of RIG-I-mediated type I interferons.
Virology
Wang T,Wei F,Jiang Z,Song J,Li C,Liu J
Thu Sep 01 00:00:00 EDT 2022
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Molecules (Basel, Switzerland)
Zhang W,Yang X,Liu J,Pan Y,Zhang M,Chen L
Mon Sep 12 00:00:00 EDT 2022
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Antioxidants (Basel, Switzerland)
Zhang J,Li Q,Zhang X,Chen Y,Lu Y,Wang X,Zhang L,Wang T
Fri Oct 07 00:00:00 EDT 2022
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Oncogene
Zheng X,Liu Z,Zhong J,Zhou L,Chen J,Zheng L,Li Z,Zhang R,Pan J,Wu Y,Liu Z,Kang T
Fri Jul 01 00:00:00 EDT 2022
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
Bioengineered
He X,Cheng X,Ding J,Xiong M,Chen B,Cao G
Tue Feb 01 00:00:00 EST 2022
Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.
Stem cell research & therapy
Parisi L,Rihs S,La Scala GC,Schnyder I,Katsaros C,Degen M
Thu Sep 08 00:00:00 EDT 2022
ERK1/2 Signalling Pathway Regulates Tubulin-Binding Cofactor B Expression and Affects Astrocyte Process Formation after Acute Foetal Alcohol Exposure.
Brain sciences
Zheng Y,Huo J,Yang M,Zhang G,Wan S,Chen X,Zhang B,Liu H
Wed Jun 22 00:00:00 EDT 2022
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Journal of pharmaceutical and biomedical analysis
Zhang M,Geng T,Jing SH,Li L,Wang K,Zhang Q,Zhang Y,Zhou SK,Gao P,Ding AW,Zhang L
Fri Aug 05 00:00:00 EDT 2022
Orientin downregulating oxidative stress-mediated endoplasmic reticulum stress and mitochondrial dysfunction through AMPK/SIRT1 pathway in rat nucleus pulposus cells in vitro and attenuated intervertebral disc degeneration in vivo.
Apoptosis : an international journal on programmed cell death
Zhang Z,Wu J,Teng C,Wang J,Yu J,Jin C,Wang L,Wu L,Lin Z,Yu Z,Lin Z
Thu Dec 01 00:00:00 EST 2022
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Chemico-biological interactions
Wu L,Li S,Li C,He B,Lv L,Wang J,Wang J,Wang W,Zhang Y
Wed Jan 05 00:00:00 EST 2022
A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection.
International journal of molecular sciences
Li C,Chen X,Hu J,Jiang D,Cai D,Li Y
Thu Dec 08 00:00:00 EST 2022
Developing a Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer.
International journal of molecular sciences
Chang Y,Funk M,Roy S,Stephenson E,Choi S,Kojouharov HV,Chen B,Pan Z
Thu Feb 03 00:00:00 EST 2022
HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation.
International journal of oncology
He Z,Gao Y,Li T,Yu C,Ou L,Luo C
Fri Apr 01 00:00:00 EDT 2022
Antitumor and Antibacterial Efficacy of Gallium Nanoparticles Coated by Ellagic Acid.
Dose-response : a publication of International Hormesis Society
El-Sonbaty SM,Moawed FS,Kandil EI,M Tamamm A
Sat Feb 19 00:00:00 EST 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Journal of cellular and molecular medicine
Yu H,Wu S,Liu S,Li X,Gai Y,Lin H,Wang Y,Edwards H,Ge Y,Wang G
Sun May 01 00:00:00 EDT 2022
Cystine Induced-mTORC2 Activation through Promoting Sin1 Phosphorylation to Suppress Cancer Cell Ferroptosis.
Molecular nutrition & food research
Wang G,Chen L,Qin S,Zheng Y,Xia C,Yao J,Wang P,Deng L
Thu Dec 01 00:00:00 EST 2022
Functional analyses of two interferon-stimulated gene 15 (ISG15) copies in large yellow croaker, Larimichthys crocea.
Fish & shellfish immunology
Shen B,Zhang S,Li F,Xu J,Zhang Y,Zhang J
Tue Nov 01 00:00:00 EDT 2022
Effect of condylar chondrocyte exosomes on condylar cartilage osteogenesis in rats under tensile stress.
Frontiers in bioengineering and biotechnology
Shi Y,Shao J,Zhang Z,Zhang J,Lu H
Sat Dec 24 00:00:00 EST 2022
KDM4C Contributes to Trophoblast-like Stem Cell Conversion from Porcine-Induced Pluripotent Stem Cells (piPSCs) via Regulating CDX2.
International journal of molecular sciences
Yu S,Shen Q,Zhang R,Wu X,Zhang J,Zhao W,Wu X,Li N,Peng S,Zhang S,Yang F,Hua J
Fri Jul 08 00:00:00 EDT 2022
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Metabolic brain disease
Ren X,Yu J,Guo L,Zhang Z
Sat Oct 01 00:00:00 EDT 2022
Downregulation of FXYD2 Is Associated with Poor Prognosis and Increased Regulatory T Cell Infiltration in Clear Cell Renal Cell Carcinoma.
Journal of immunology research
Zhang Z,Tang Y,Li L,Yang W,Xu Y,Zhou J,Ma K,Zhang K,Zhuang H,Gong Y,Gong K
Tue Nov 01 00:00:00 EDT 2022
Berberine prevents lethal EV71 neurological infection in newborn mice.
Frontiers in pharmacology
Cui G,Wang H,Yang C,Zhou X,Wang J,Wang T,Ma T
Fri Nov 18 00:00:00 EST 2022
Evacetrapib Elicits Antitumor Effects on Colorectal Cancer by Inhibiting the Wnt/β-Catenin Signaling Pathway and Activating the JNK Signaling Pathway.
Biological & pharmaceutical bulletin
Hu L,Dong H,He L,Shi M,Xiang N,Su Y,Wang C,Tian Y,Hu Y,Wang H,Liu H,Wen C,Yang X
Thu Sep 08 00:00:00 EDT 2022
Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis.
Cell death discovery
Zhuang L,Luo X,Wu S,Lin Z,Zhang Y,Zhai Z,Yang F,Li Y,Zhuang J,Luo G,Xu W,He Y,Sun E
Sat Sep 03 00:00:00 EDT 2022
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
Cancer cell international
Yu B,Liu L,Cai F,Peng Y,Tang X,Zeng D,Li T,Zhang F,Liang Y,Yuan X,Li J,Dai Z,Liao Q,Lv XB
Tue Feb 08 00:00:00 EST 2022
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
Journal of cardiovascular translational research
Xu Y,Chen R,Yan J,Zang G,Shao C,Wang Z
Sat Oct 01 00:00:00 EDT 2022
BMP6 Promotes the Secretion of 17 Beta-Estradiol and Progesterone in Goat Ovarian Granulosa Cells.
Animals : an open access journal from MDPI
Song S,Ding W,Yao H,Wang L,Li B,Wang Y,Tang X,Zhang Y,Huang D,Xu D,Zhao Z
Fri Aug 19 00:00:00 EDT 2022
Basolateral Amygdala Reactive Microglia May Contribute to Synaptic Impairment and Depressive-Like Behavior in Mice with Bone Cancer Pain.
Neurochemical research
Jiang L,Hao J,Yang XL,Zhu JX,Wang Y,Huang YL,Sun YE,Mao YT,Ni K,Gu XP,Ma ZL
Tue Nov 01 00:00:00 EDT 2022
Tnfaip2 promotes atherogenesis by enhancing oxidative stress induced inflammation.
Molecular immunology
Jin G,Liu Y,Xu W,Li Y,Zhang H,Qiu S,Gao C,Liu S
Tue Nov 01 00:00:00 EDT 2022
Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition.
Molecular neurobiology
Wang S,Jiang Y,Liu Y,Liu Q,Sun H,Mei M,Liao X
Tue Mar 01 00:00:00 EST 2022
The combination of decitabine and aspirin inhibits tumor growth and metastasis in non-small cell lung cancer.
The Journal of international medical research
Xu M,Song B,Yang X,Li N
Fri Jul 01 00:00:00 EDT 2022
Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity.
Oxidative medicine and cellular longevity
Fang J,Li L,Cao X,Yue H,Fu W,Chen Y,Xu Z,Zhao Q,Zhao J,Wang Y,Liang W
Tue Aug 30 00:00:00 EDT 2022
Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3.
Free radical biology & medicine
Zhang Q,Ren J,Wang F,Pan M,Cui L,Li M,Qu F
Fri Jul 01 00:00:00 EDT 2022
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression.
Molecular brain
Xue WJ,He CF,Zhou RY,Xu XD,Xiang LX,Wang JT,Wang XR,Zhou HG,Guo JC
Mon Jul 18 00:00:00 EDT 2022
MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis.
Cell death discovery
Ma H,Xie C,Chen Z,He G,Dai Z,Cai H,Zhang H,Lu H,Wu H,Hu X,Zhou K,Zheng G,Xu H,Xu C
Tue Apr 19 00:00:00 EDT 2022
Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
Scientific reports
Otani N,Tomita K,Kobayashi Y,Kuroda K,Koyama Y,Kobayashi H,Kubo T
Wed Apr 13 00:00:00 EDT 2022
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang L,Kong L,Xu S,Wang X,Huang K,Wang S,Wu J,Wang C,Sun H,Liu K,Meng Q
Tue Feb 01 00:00:00 EST 2022
miR-186-5p Dysregulation in Serum Exosomes from Patients with AMI Aggravates Atherosclerosis via Targeting LOX-1.
International journal of nanomedicine
Ding J,Li H,Liu W,Wang X,Feng Y,Guan H,Chen Z
Thu Dec 29 00:00:00 EST 2022
Comprehensive Analysis of the Potential Immune-Related Biomarker ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After Photodynamic Therapy.
Frontiers in pharmacology
Zhang ZJ,Wang KP,Huang YP,Jin C,Jiang H,Xiong L,Chen ZY,Wen Y,Liu ZT,Mo JG
Sat Jul 16 00:00:00 EDT 2022
Ginkgo biloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways.
Chinese medicine
Wei C,Zhang Y,Zhong X,Lu S,Zou X,Yang Y,Huang S,Huang Z
Mon Feb 21 00:00:00 EST 2022
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Frontiers in pharmacology
Hu Z,Wang Y,Gao X,Zhang Y,Liu C,Zhai Y,Chang X,Li H,Li Y,Lou J,Li C
Sat Sep 17 00:00:00 EDT 2022
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Frontiers in pharmacology
Wang J,Wang K,Ding L,Zhao P,Zhang C,Wang H,Yang Z,Liu Z
Tue Aug 30 00:00:00 EDT 2022
Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-κB Activation through Phosphorylated STAT3-TET3 Signaling.
The Journal of investigative dermatology
Ling S,Xu B,Luo Y,Fang X,Liu X,Wang A,Zhou Y,Zhang S,Zong W,Li W,Yao X
Tue Nov 01 00:00:00 EDT 2022
Systematic characterization of the metabolites of defatted walnut powder extract in vivo and screening of the mechanisms against NAFLD by UPLC-Q-Exactive Orbitrap MS combined with network pharmacology.
Journal of ethnopharmacology
Ren SM,Zhang QZ,Jiang M,Chen ML,Xu XJ,Wang DM,Pan YN,Liu XQ
Tue Mar 01 00:00:00 EST 2022
Preliminary evaluation of a small interfering RNA molecular probe targeting murine double minute 2 in breast cancer.
Nuclear medicine communications
Wang X,Xu P,Jiao Y,Luan S,Gao Y,Zhao C,Fu P
Mon Aug 01 00:00:00 EDT 2022
GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca2+-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy.
Biomolecules
Li Y,Li HY,Shao J,Zhu L,Xie TH,Cai J,Wang W,Cai MX,Wang ZL,Yao Y,Wei TT
Tue Nov 29 00:00:00 EST 2022
SPATA33 affects the formation of cell adhesion complex by interacting with CTNNA3 in TM4 cells.
Cell and tissue research
Zhang Y
Fri Jul 01 00:00:00 EDT 2022
Loureirin C ameliorates ischemia and reperfusion injury in rats by inhibiting the activation of the TLR4/NF-κB pathway and promoting TLR4 degradation.
Phytotherapy research : PTR
Xu J,Liu J,Li Q,Mi Y,Zhou D,Wang J,Chen G,Liang D,Li N,Hou Y
Thu Dec 01 00:00:00 EST 2022
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
Biochemical pharmacology
Zhang B,Fu R,Duan Z,Shen S,Zhu C,Fan D
Mon Aug 01 00:00:00 EDT 2022
Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification.
Journal of nanobiotechnology
Guo B,Shan SK,Xu F,Lin X,Li FX,Wang Y,Xu QS,Zheng MH,Lei LM,Li CC,Zhou ZA,Ullah MHE,Wu F,Liao XB,Yuan LQ
Sat Jul 16 00:00:00 EDT 2022
Epigenetic silencing of JAM3 promotes esophageal cancer development by activating Wnt signaling.
Clinical epigenetics
Yang W,Guo C,Herman JG,Zhu C,Lv H,Su X,Zhang L,Zhang M,Guo M
Fri Dec 02 00:00:00 EST 2022
Novel bioactive hybrid Celecoxib-HDAC Inhibitor, induces apoptosis in human acute lymphoblastic leukemia cells.
Bioorganic & medicinal chemistry
Liu J,Zhang L,Guo L,Zeng Y,Guo Q,Yang C,Shu J,Liu W,Yang L
Thu Dec 01 00:00:00 EST 2022
Isolation, characterization, and functional study of extracellular vesicles derived from Leishmania tarentolae.
Frontiers in cellular and infection microbiology
Shokouhy M,Sarvnaz H,Taslimi Y,Lajevardi MS,Habibzadeh S,Mizbani A,Shekari F,Behbahani M,Torrecilhas AC,Rafati S
Tue Aug 23 00:00:00 EDT 2022
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Life sciences
Liu J,Li D,Dun Y,Li H,Ripley-Gonzalez JW,Zhang J,Qiu L,You B,Liu S
Tue Nov 01 00:00:00 EDT 2022
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis.
Chinese medicine
Li X,Zhao T,Gu J,Wang Z,Lin J,Wang R,Duan T,Li Z,Dong R,Wang W,Hong KF,Liu Z,Huang W,Gui D,Zhou H,Xu Y
Sat Feb 12 00:00:00 EST 2022
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
European journal of pharmacology
Zhu X,Peng J,Yang L,Guo Y,Wang P,Liu K,Zhu J,Deng S,Liang M
Sat Oct 15 00:00:00 EDT 2022
Neonatal gene therapy achieves sustained disease rescue of maple syrup urine disease in mice.
Nature communications
Pontoizeau C,Simon-Sola M,Gaborit C,Nguyen V,Rotaru I,Tual N,Colella P,Girard M,Biferi MG,Arnoux JB,Rötig A,Ottolenghi C,de Lonlay P,Mingozzi F,Cavazzana M,Schiff M
Tue Jun 07 00:00:00 EDT 2022
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Cell metabolism
Rosina M,Ceci V,Turchi R,Chuan L,Borcherding N,Sciarretta F,Sánchez-Díaz M,Tortolici F,Karlinsey K,Chiurchiù V,Fuoco C,Giwa R,Field RL,Audano M,Arena S,Palma A,Riccio F,Shamsi F,Renzone G,Verri M,Crescenzi A,Rizza S,Faienza F,Filomeni G,Kooijman S,Rufini S,de Vries AAF,Scaloni A,Mitro N,Tseng YH,Hidalgo A,Zhou B,Brestoff JR,Aquilano K,Lettieri-Barbato D
Tue Apr 05 00:00:00 EDT 2022
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Molecular neurobiology
Yang X,Wang M,Zhou Q,Bai Y,Liu J,Yang J,Li L,Li G,Luo L
Sun May 01 00:00:00 EDT 2022
Angiotensin II type-2 receptor activation in alveolar macrophages mediates protection against cigarette smoke-induced chronic obstructive pulmonary disease.
Pharmacological research
Mei D,Liao W,Gan PXL,Tran QTN,Chan CCMY,Heng CKM,Wong WSF
Sat Oct 01 00:00:00 EDT 2022
Identification of oncogenes and tumor-suppressor genes with hepatocellular carcinoma: A comprehensive analysis based on TCGA and GEO datasets.
Frontiers in genetics
Zhu Y,Wang Y,Hu M,Lu X,Sun G
Thu Feb 02 00:00:00 EST 2023
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Journal of diabetes research
Li H,Wang Y,Su X,Wang Q,Zhang S,Sun W,Zhang T,Dong M,Zhang Z,Lv S
Mon Nov 28 00:00:00 EST 2022
Novel Antiviral Activity of Ethyl 3-Hydroxyhexanoate Against Coxsackievirus B Infection.
Frontiers in microbiology
Olasunkanmi OI,Mageto J,Avala Ntsigouaye J,Yi M,Fei Y,Chen Y,Chen S,Xu W,Lin L,Zhao W,Wang Y,Zhong ZH
Tue May 03 00:00:00 EDT 2022
Parkin-mediated mitophagy protects against TNF-α-induced stress in bone marrow mesenchymal stem cells.
Experimental gerontology
Fan P,Yu XY,Chen CH,Gao JW,Xu YZ,Xie XH,Wang YT
Fri Jul 01 00:00:00 EDT 2022
Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair.
Nature communications
Wang P,Huang Z,Peng Y,Li H,Lin T,Zhao Y,Hu Z,Zhou Z,Zhou W,Liu Y,Hou FF
Mon Oct 31 00:00:00 EDT 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 EDT 2022
Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1β-Induced Endothelium Injury.
Antioxidants (Basel, Switzerland)
Li YC,Li Y,Zhang YN,Zhao Q,Zhang PL,Sun MR,Liu BL,Yang H,Li P
Tue Jul 26 00:00:00 EDT 2022
Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.
Pharmacological research
Yin A,Feng M,Zhang L,Cheng Z,Li Y,Qian L
Sat Jan 01 00:00:00 EST 2022
Identification of cytochrome c oxidase subunit 4 isoform 1 as a positive regulator of influenza virus replication.
Frontiers in microbiology
He J,Huang H,Li B,Li H,Zhao Y,Li Y,Ye W,Qi W,Tang W,Wang L
Sat Aug 06 00:00:00 EDT 2022
TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos.
Molecular medicine (Cambridge, Mass.)
Duan Y,Fu H,Huang J,Yin N,Liu L,Liu X
Fri Dec 30 00:00:00 EST 2022
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
Frontiers in pharmacology
Peng L,Chen Y,Li Y,Feng P,Zheng Y,Dong Y,Yang Y,Wang R,Li A,Yan J,Shang F,Tang P,Chen D,Gao Y,Huang W
Tue Apr 05 00:00:00 EDT 2022
Gestational bisphenol A exposure impairs hepatic lipid metabolism by altering mTOR/CRTC2/SREBP1 in male rat offspring.
Human & experimental toxicology
Yang Q,Mao Y,Wang J,Yu H,Zhang X,Pei X,Duan Z,Xiao C,Ma M
Mon Sep 26 00:00:00 EDT 2022
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Journal of applied toxicology : JAT
Liu YP,Yuan XY,Li XY,Wang Y,Sun ZB,Deng WH,Lei YD,Huang L,Jiang TY,Zhang ZH
Tue Feb 01 00:00:00 EST 2022
Pectin supplement alleviates gut injury potentially through improving gut microbiota community in piglets.
Frontiers in microbiology
Dang G,Wang W,Zhong R,Wu W,Chen L,Zhang H
Tue Jan 03 00:00:00 EST 2023
Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis rats by inhibiting Th1/Th17 immune responses.
Journal of reproductive immunology
Zhu Q,Muyayalo KP,Xu QH,Wang J,Wang H,Liao AH
Tue Feb 01 00:00:00 EST 2022
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
Experimental neurology
Xie Y,Zou X,Han J,Zhang Z,Feng Z,Ouyang Q,Hua S,Liu Z,Li C,Cai Y,Zou Y,Tang Y,Jiang X
Fri Jul 01 00:00:00 EDT 2022
Circadian Rhythm Disorders Aggravate Periodontitis by Modulating BMAL1.
International journal of molecular sciences
Liu X,Cao N,Liu X,Deng Y,Xin Y,Fu R,Xin X,Hou Y,Yu W
Mon Dec 26 00:00:00 EST 2022
Effects of iron oxide nanoparticles as T2-MRI contrast agents on reproductive system in male mice.
Journal of nanobiotechnology
Yang H,Wang H,Wen C,Bai S,Wei P,Xu B,Xu Y,Liang C,Zhang Y,Zhang G,Wen H,Zhang L
Wed Mar 02 00:00:00 EST 2022
Moxibustion alleviates decreased ovarian reserve in rats by restoring the PI3K/AKT signaling pathway.
Journal of integrative medicine
Li HX,Shi L,Liang SJ,Fang CC,Xu QQ,Lu G,Wang Q,Cheng J,Shen J,Shen MH
Tue Mar 01 00:00:00 EST 2022
STING-mediated inflammation contributes to Gao binge ethanol feeding model.
Journal of cellular physiology
Wang L,You HM,Meng HW,Pan XY,Chen X,Bi YH,Zhang YF,Li JJ,Yin NN,Zhang ZW,Huang C,Li J
Tue Feb 01 00:00:00 EST 2022
Trans-Anethole Alleviates Subclinical Necro-Haemorrhagic Enteritis-Induced Intestinal Barrier Dysfunction and Intestinal Inflammation in Broilers.
Frontiers in microbiology
Yu C,Wang D,Tong Y,Li Q,Yang W,Wang T,Yang Z
Fri Apr 08 00:00:00 EDT 2022
Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models.
Acta pharmacologica Sinica
Chen D,Zhang HF,Yuan TY,Sun SC,Wang RR,Wang SB,Fang LH,Lyu Y,Du GH
Thu Sep 01 00:00:00 EDT 2022
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
Cancer letters
You B,Zhang P,Gu M,Yin H,Fan Y,Yao H,Pan S,Xie H,Cheng T,Liu H,You Y,Liu J
Sun Apr 10 00:00:00 EDT 2022
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Cell death and differentiation
Xie W,Guo D,Li J,Yue L,Kang Q,Chen G,Zhou T,Wang H,Zhuang K,Leng L,Li H,Chen Z,Gao W,Zhang J
Thu Dec 01 00:00:00 EST 2022
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Molecular and cellular endocrinology
Xi H,Ren F,Li Y,Xian M,Wang L,Hu J
Sat Jan 15 00:00:00 EST 2022
SRA Suppresses Antiviral Innate Immune Response in Macrophages by Limiting TBK1 K63 Ubiquitination via Deubiquitinase USP15.
Microbiology spectrum
Li L,Luo J,Zhu Z,Xu Q,Wang P,Chang B,Wang D,Yu L,Lu X,Zhou J,Zuo D,Chen Q
Wed Dec 21 00:00:00 EST 2022
Aucubin promotes bone-fracture healing via the dual effects of anti-oxidative damage and enhancing osteoblastogenesis of hBM-MSCs.
Stem cell research & therapy
Wang K,Zhou C,Li L,Dai C,Wang Z,Zhang W,Xu J,Zhu Y,Pan Z
Fri Aug 19 00:00:00 EDT 2022
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
International immunopharmacology
Chen S,Qian S,Zhang L,Pan X,Qu F,Yu Y,Gu Z,Cui X,Shen H
Sat Oct 01 00:00:00 EDT 2022
Evodiamine suppresses the progression of non-small cell lung carcinoma via endoplasmic reticulum stress-mediated apoptosis pathway in vivo and in vitro.
International journal of immunopathology and pharmacology
Li Y,Wang Y,Wang X,Jin L,Yang L,Zhu J,Wang H,Zheng F,Cui H,Li X,Jia Y
Fri Apr 08 00:00:00 EDT 2022
MicroRNA-200c Affects Milk Fat Synthesis by Targeting PANK3 in Ovine Mammary Epithelial Cells.
International journal of molecular sciences
Hao Z,Wang J,Luo Y,Hu J,Liu X,Li S,Li M,Shi B,Hu L,Liu Y,Zhen H
Fri Dec 09 00:00:00 EST 2022
Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma.
Frontiers in oncology
Zhu T,Wang T,Feng Z,Gao F,Zhang J,Jin C,Tian H,Xu J,Chen H,Ou Q,Wang J,Xu G,Lu L
Fri Jul 22 00:00:00 EDT 2022
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kang H,Guo Q,Dong Y,Peng R,Song K,Wang J,Liu H,Zhu M,Zhao H,Guan H,Li F
Tue Feb 01 00:00:00 EST 2022
MiR-328-5p inhibits the adipogenic differentiation of hMSCs by targeting fatty acid synthase.
Folia histochemica et cytobiologica
Li X,He S,Wu P,Zhou Y,Long K,Wang T
Mon Jan 02 00:00:00 EST 2023
125I seeds inhibit proliferation and promote apoptosis in cholangiocarcinoma cells by regulating the AGR2-mediated p38 MAPK pathway.
Cancer letters
Zhou X,Zhang W,Dou M,Li Z,Liu Z,Li J,Tian C,Yao Y,Wang C,Li Y,Chen P,Han X,Jiao D
Sat Jan 01 00:00:00 EST 2022
BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBα in mice.
International journal of biological sciences
Li F,Lin L,He Y,Sun G,Dong D,Wu B
Thu Apr 14 00:00:00 EDT 2022
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension.
Journal of cellular and molecular medicine
Deng H,Tian X,Sun H,Liu H,Lu M,Wang H
Sun May 01 00:00:00 EDT 2022
Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.
Frontiers in immunology
Gu L,Sun M,Li R,Zhang X,Tao Y,Yuan Y,Luo X,Xie Z
Mon Mar 14 00:00:00 EDT 2022
Arsenic exposure via drinking water during pregnancy and lactation induces autism-like behaviors in male offspring mice.
Chemosphere
Zhang X,Mei D,Li Y,You M,Wang D,Yao D,Xu Y,Zhai L,Wang Y
Tue Mar 01 00:00:00 EST 2022
Nrf2 Overexpression Decreases Vincristine Chemotherapy Sensitivity Through the PI3K-AKT Pathway in Adult B-Cell Acute Lymphoblastic Leukemia.
Frontiers in oncology
Wang L,Liu X,Kang Q,Pan C,Zhang T,Feng C,Chen L,Wei S,Wang J
Sat Jul 16 00:00:00 EDT 2022
P2X7R/NLRP3 signaling pathway-mediated pyroptosis and neuroinflammation contributed to cognitive impairment in a mouse model of migraine.
The journal of headache and pain
Wang Y,Shan Z,Zhang L,Fan S,Zhou Y,Hu L,Wang Y,Li W,Xiao Z
Sat Jul 02 00:00:00 EDT 2022
Altered Liver Metabolism, Mitochondrial Function, Oxidative Status, and Inflammatory Response in Intrauterine Growth Restriction Piglets with Different Growth Patterns before Weaning.
Metabolites
Wang J,Zhu P,Zheng X,Ma Z,Cui C,Wu C,Zeng X,Guan W,Chen F
Tue Nov 01 00:00:00 EDT 2022
Integrated Bioinformatic Analysis Reveals TXNRD1 as a Novel Biomarker and Potential Therapeutic Target in Idiopathic Pulmonary Arterial Hypertension.
Frontiers in medicine
Lin W,Tang Y,Zhang M,Liang B,Wang M,Zha L,Yu Z
Mon Jan 02 00:00:00 EST 2023
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
Food & function
He H,Liu M,He R,Zhao W
Mon Oct 03 00:00:00 EDT 2022
MiR-103a-3p Promotes Zika Virus Replication by Targeting OTU Deubiquitinase 4 to Activate p38 Mitogen-Activated Protein Kinase Signaling Pathway.
Frontiers in microbiology
Ye H,Kang L,Yan X,Li S,Huang Y,Mu R,Duan X,Chen L
Thu Mar 24 00:00:00 EDT 2022
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia.
Journal of nanobiotechnology
Lin L,Song C,Wei Z,Zou H,Han S,Cao Z,Zhang X,Zhang G,Ran J,Cai Y,Han W
Fri Mar 04 00:00:00 EST 2022
DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity.
Oncogene
Chen B,Xu F,Gao Y,Hu G,Zhu K,Lu H,Xu A,Chen S,Wu L,Zhao G
Tue Mar 01 00:00:00 EST 2022
MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.
Bioengineered
Liu M,Du Q,Mao G,Dai N,Zhang F
Tue Mar 01 00:00:00 EST 2022
Human Amnion Epithelial Cells and Their Derived Exosomes Alleviate Sepsis-Associated Acute Kidney Injury via Mitigating Endothelial Dysfunction.
Frontiers in medicine
Chi D,Chen Y,Xiang C,Yao W,Wang H,Zheng X,Xu D,Li N,Xie M,Wang S,Liu G,Li S,Yang L
Wed Apr 13 00:00:00 EDT 2022
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
International journal of biological sciences
Huang G,Xiang Z,Wu H,He Q,Dou R,Lin Z,Yang C,Huang S,Song J,Di Z,Wang S,Xiong B
Fri Apr 15 00:00:00 EDT 2022
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Acta histochemica
Lian N,Jin H,Zhu W,Zhang C,Qi Y,Jiang M,Mao J,Lu X,Zhao F,Xi B,Qi X,Li Y
Thu Dec 01 00:00:00 EST 2022
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
International immunopharmacology
Han F,Shen L,Ma H,Wang L,Guo H,Wu X
Thu Dec 01 00:00:00 EST 2022
ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats.
Oxidative medicine and cellular longevity
Li Y,Wu F,Zhou M,Zhou J,Cui S,Guo J,Wu J,He L
Mon Apr 11 00:00:00 EDT 2022
Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.
Frontiers in pharmacology
Li W,Li M,Chen K,Tang Y,Yin R,Lan L,Hong G
Wed Nov 02 00:00:00 EDT 2022
Vitamin D Deficiency Impacts Exposure and Response of Pravastatin in Male Rats by Altering Hepatic OATPs.
Frontiers in pharmacology
Peng J,Yang G,Huang Z
Tue Mar 08 00:00:00 EST 2022
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Oncology letters
Gong J,Shen Y,Jiang F,Wang Y,Chu L,Sun J,Shen P,Chen M
Sun May 01 00:00:00 EDT 2022
Inhibition of Bruton's Tyrosine Kinase Alleviates Monocrotaline-Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization.
Oxidative medicine and cellular longevity
Yu M,Wu X,Peng L,Yang M,Zhou H,Xu J,Wang J,Wang H,Xie W,Kong H
Fri Sep 09 00:00:00 EDT 2022
Olanzapine-induced lipid disturbances: A potential mechanism through the gut microbiota-brain axis.
Frontiers in pharmacology
Zhu Z,Gu Y,Zeng C,Yang M,Yu H,Chen H,Zhang B,Cai H
Tue Aug 23 00:00:00 EDT 2022
Salidroside Ameliorates Radiation Damage by Reducing Mitochondrial Oxidative Stress in the Submandibular Gland.
Antioxidants (Basel, Switzerland)
Sun YM,Wang XY,Zhou XR,Zhang C,Liu KJ,Zhang FY,Xiang B
Thu Jul 21 00:00:00 EDT 2022
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
EBioMedicine
Zhang L,Shi J,Du D,Niu N,Liu S,Yang X,Lu P,Shen X,Shi N,Yao L,Zhang R,Hu G,Lu G,Zhu Q,Zeng T,Liu T,Xia Q,Huang W,Xue J
Fri Apr 01 00:00:00 EDT 2022
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ma H,Duan X,Zhang R,Li H,Guo Y,Tian Y,Huang M,Chen G,Wang Z,Li L
Thu Dec 21 00:00:00 EST 2023
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Oxidative medicine and cellular longevity
Li C,Zhu L,Dai Y,Zhang Z,Huang L,Wang TJ,Fu P,Li Y,Wang J,Jiang C
Thu Mar 24 00:00:00 EDT 2022
Development and Validation of Novel Prognostic Models for Immune-Related Genes in Osteosarcoma.
Frontiers in molecular biosciences
Li J,Su L,Xiao X,Wu F,Du G,Guo X,Kong F,Yao J,Zhu H
Sat Jul 16 00:00:00 EDT 2022
Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.
Stem cell research & therapy
Gao Z,Zhang C,Peng F,Chen Q,Zhao Y,Chen L,Wang X,Chen X
Sat May 07 00:00:00 EDT 2022
A plant-derived natural photosynthetic system for improving cell anabolism.
Nature
Chen P,Liu X,Gu C,Zhong P,Song N,Li M,Dai Z,Fang X,Liu Z,Zhang J,Tang R,Fan S,Lin X
Thu Dec 01 00:00:00 EST 2022
Niban apoptosis regulator 1 promotes gemcitabine resistance by activating the focal adhesion kinase signaling pathway in bladder cancer.
Journal of Cancer
Tong S,Yin H,Fu J,Li Y
Tue Mar 15 00:00:00 EDT 2022
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
International journal of molecular sciences
Zhang Y,Shen Y,Wei W,Wang W,Jiang D,Ren Y,Peng Z,Fan Q,Cheng J,Ma J
Wed Jul 27 00:00:00 EDT 2022
Combinatorial approaches for mitigating resistance to KRAS-targeted therapies.
The Biochemical journal
Warren HR,Ross SJ,Smith PD,Coulson JM,Prior IA
Fri Sep 30 00:00:00 EDT 2022
Effects of STAT3 Inhibitor BP-1-102 on The Proliferation, Invasiveness, Apoptosis and Neurosphere Formation of Glioma Cells in Vitro.
Cell biochemistry and biophysics
Zhang CC,Wu T,Guan L,Wang YJ,Yao RQ,Gao DS,Li F
Thu Dec 01 00:00:00 EST 2022
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
Cell death & disease
Yin X,Peng J,Gu L,Liu Y,Li X,Wu J,Xu B,Zhuge Y,Zhang F
Mon Nov 14 00:00:00 EST 2022
An electrochemical nitric oxide generator for in-home inhalation therapy in pulmonary artery hypertension.
BMC medicine
Liu Y,Zhu Y,Jiang C,Su Z,Yan Y,Feng B,Mao W,Zhang Y,Wang X,Xu Z,Zhang H
Thu Dec 15 00:00:00 EST 2022
Artesunate Inhibits the Cell Growth in Colorectal Cancer by Promoting ROS-Dependent Cell Senescence and Autophagy.
Cells
Huang Z,Gan S,Zhuang X,Chen Y,Lu L,Wang Y,Qi X,Feng Q,Huang Q,Du B,Zhang R,Liu Z
Tue Aug 09 00:00:00 EDT 2022
Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model.
International journal of molecular sciences
Rodrigues L,Wartchow KM,Buchfelder M,Souza DO,Gonçalves CA,Kleindienst A
Wed Aug 24 00:00:00 EDT 2022
Mettl3 regulates hypertrophic differentiation of chondrocytes through modulating Dmp1 mRNA via Ythdf1-mediated m6A modification.
Bone
He Y,Wang W,Luo P,Wang Y,He Z,Dong W,Jia M,Yu X,Yang B,Wang J
Tue Nov 01 00:00:00 EDT 2022
Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis.
Oxidative medicine and cellular longevity
Shi X,Zhu L,Wang S,Zhu W,Li Q,Wei J,Feng D,Liu M,Chen Y,Sun X,Lu H,Lv X
Tue May 10 00:00:00 EDT 2022
Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-κB Pathway.
Neurochemical research
Deng L,Jiang J,Chen S,Lin X,Zuo T,Hu Q,Wu Y,Fan X,Dong Z
Fri Jul 01 00:00:00 EDT 2022
The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease.
Life sciences
Junli Z,Shuhan W,Yajuan Z,Xiaoling D,Jiahuan L,Keshu X
Sat Oct 01 00:00:00 EDT 2022
Curcumin regulates anti-inflammatory responses by AXL/JAK2/STAT3 signaling pathway in experimental autoimmune encephalomyelitis.
Neuroscience letters
Sun M,Liu N,Sun J,Li X,Wang H,Zhang W,Xie Q,Wang M
Wed Sep 14 00:00:00 EDT 2022
Corrigendum to "Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway".
Evidence-based complementary and alternative medicine : eCAM
Ding B,Geng S,Hou X,Ma X,Xu H,Yang F,Liu K,Liang W,Ma G
Thu Aug 18 00:00:00 EDT 2022
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
Renal failure
He S,Zhou M,Zheng H,Wang Y,Wu S,Gao Y,Chen J
Thu Dec 01 00:00:00 EST 2022
PM2.5-Induced Programmed Myocardial Cell Death via mPTP Opening Results in Deteriorated Cardiac Function in HFpEF Mice.
Cardiovascular toxicology
Wu T,Tong M,Chu A,Wu K,Niu X,Zhang Z
Mon Aug 01 00:00:00 EDT 2022
Ellagic Acid Alleviates Mice Intestinal Ischemia-Reperfusion Injury: A Study Based on Transcriptomics Combined with Functional Experiments.
Chemistry & biodiversity
Fan S,Xu Y,Li K,Li B,Diao Y
Tue Nov 01 00:00:00 EDT 2022
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Food chemistry
Hu S,Hu C,Luo L,Zhang H,Zhao S,Liu Z,Zeng L
Tue Nov 15 00:00:00 EST 2022
Roles of C/EBP-homologous protein and histone H3 lysine 4 methylation in arsenic-induced mitochondrial apoptosis in hepatocytes.
Toxicology and industrial health
Liang C,Xie RJ,Wang JL,Zhang YW,Zhang JY,Yang Q,Han B
Tue Nov 01 00:00:00 EDT 2022
Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation.
Viruses
Liu Y,Wang X,Wang J,Zhang J,Duan C,Wang J
Tue Feb 15 00:00:00 EST 2022
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Human molecular genetics
Jin Y,Gao X,Lu M,Chen G,Yang X,Ren N,Song Y,Hou C,Li J,Liu Q,Gao J
Mon Oct 10 00:00:00 EDT 2022
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
Neurochemical research
Zhang H,Yu S,Xia L,Peng X,Wang S,Yao B
Tue Mar 01 00:00:00 EST 2022
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Frontiers in molecular neuroscience
Lu Y,Li B,Xu A,Liang X,Xu T,Jin H,Xie Y,Wang R,Liu X,Gao X,Han Y,Zeng J
Tue Aug 16 00:00:00 EDT 2022
Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Li Z,Ma D,Wang Y,Wu S,Wang L,Jiang Y,Zhang Y,Li X
Sun May 01 00:00:00 EDT 2022
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Metabolites
Liu M,Yue Z,Zhang B,Li F,Liu L,Li F
Thu Aug 25 00:00:00 EDT 2022
Structural Variability of Lipoarabinomannan Modulates Innate Immune Responses within Infected Alveolar Epithelial Cells.
Cells
Liu H,Gui X,Chen S,Fu W,Li X,Xiao T,Hou J,Jiang T
Fri Jan 21 00:00:00 EST 2022
P53 maintains gallid alpha herpesvirus 1 replication by direct regulation of nucleotide metabolism and ATP synthesis through its target genes.
Frontiers in microbiology
Xu L,Chen Z,Zhang Y,Cui L,Liu Z,Li X,Liu S,Li H
Tue Dec 20 00:00:00 EST 2022
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
Brain research
Li M,Zhong X,Zhao Z,Zeng Z,Yuan Q,Xiao X,Zu X,Liu J
Tue Feb 15 00:00:00 EST 2022
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhong Y,Luo R,Liu Q,Zhu J,Lei M,Liang X,Wang X,Peng X
Sat Jan 01 00:00:00 EST 2022
MicroRNA-122a aggravates intestinal ischemia/reperfusion injury by promoting pyroptosis via targeting EGFR-NLRP3 signaling pathway.
Life sciences
Wang F,Gu L,Wang Y,Sun D,Zhao Y,Meng Q,Yin L,Xu L,Lu X,Peng J,Lin Y,Sun P
Sat Oct 15 00:00:00 EDT 2022
Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway.
Journal of virology
Huang S,Huang J,Cui M,Wu X,Wang M,Zhu D,Chen S,Liu M,Zhao X,Wu Y,Yang Q,Zhang S,Ou X,Mao S,Gao Q,Yu Y,Tian B,Liu Y,Zhang L,Yin Z,Jing B,Chen X,Cheng A,Jia R
Wed Sep 28 00:00:00 EDT 2022
Genome-wide association studies identify miRNA-194 as a prognostic biomarker for gastrointestinal cancer by targeting ATP6V1F, PPP1R14B, BTF3L4 and SLC7A5.
Frontiers in oncology
Huang P,Xia L,Guo Q,Huang C,Wang Z,Huang Y,Qin S,Leng W,Li D
Wed Jan 11 00:00:00 EST 2023
Overexpression of NCAPG in ovarian cancer is associated with ovarian cancer proliferation and apoptosis via p38 MAPK signaling pathway.
Journal of ovarian research
Yu H,Zou D,Ni N,Zhang S,Zhang Q,Yang L
Fri Aug 19 00:00:00 EDT 2022
Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasome.
Journal of bioscience and bioengineering
Pei Y,Cheng F,Li W,Yu Q,Ma C,Zou Y,Xu T,Liu S,Zhang S,Wang Q
Tue Feb 01 00:00:00 EST 2022
Probing the Potential Mechanism of Quercetin and Kaempferol against Heat Stress-Induced Sertoli Cell Injury: Through Integrating Network Pharmacology and Experimental Validation.
International journal of molecular sciences
Liu DL,Liu SJ,Hu SQ,Chen YC,Guo J
Thu Sep 22 00:00:00 EDT 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Lgr5 + cell fate regulation by coordination of metabolic nuclear receptors during liver repair.
Theranostics
Qin D,Liu S,Lu Y,Yan Y,Zhang J,Cao S,Chen M,Chen N,Huang W,Wang L,Chen X,Zhang L
Thu Sep 29 00:00:00 EDT 2022
KIAA1199 Correlates With Tumor Microenvironment and Immune Infiltration in Lung Adenocarcinoma as a Potential Prognostic Biomarker.
Pathology oncology research : POR
Shen X,Mo X,Tan W,Mo X,Li L,Yu F,He J,Deng Z,Xing S,Chen Z,Yang J
Thu Dec 01 00:00:00 EST 2022
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Gao Y,Hu M,Niu X,Li M,Xu L,Xiao Y,Zhang J,Wang H,Li L,Chu B,Lv P
Tue Dec 13 00:00:00 EST 2022
Clostridium butyricum inhibits the progression of colorectal cancer and alleviates intestinal inflammation via the myeloid differentiation factor 88 (MyD88)-nuclear factor-kappa B (NF-κB) signaling pathway.
Annals of translational medicine
Zhou M,Yuan W,Yang B,Pei W,Ma J,Feng Q
Fri Apr 01 00:00:00 EDT 2022
Rhein Inhibits the Progression of Chemoresistant Lung Cancer Cell Lines via the Stat3/Snail/MMP2/MMP9 Pathway.
BioMed research international
Liu J,Ding D,Liu F,Chen Y
Thu Mar 31 00:00:00 EDT 2022
Detection of netrin-1 as a novel biomarker for diagnosis and chemotherapeutic monitoring of lung cancer.
The Journal of international medical research
Zhao Y,Song J,Ding X,Hao Y,Cao L
Wed Jun 01 00:00:00 EDT 2022
Effects of the probiotic, Lactobacillus rhamnosus GG, on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer.
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Isik M,Ozbayer C,Donmez DB,Colak E,Ustuner MC,Erol K,Degirmenci I
Mon Aug 01 00:00:00 EDT 2022
Systematic analyses identify the anti-fibrotic role of lncRNA TP53TG1 in IPF.
Cell death & disease
Sun J,Guo Y,Chen T,Jin T,Ma L,Ai L,Guo J,Niu Z,Yang R,Wang Q,Yu X,Gao H,Zhang Y,Su W,Song X,Ji W,Zhang Q,Huang M,Fan X,Du Z,Liang H
Sat Jun 04 00:00:00 EDT 2022
ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway.
Virology journal
Zhang K,Wang S,Chen T,Tu Z,Huang X,Zang G,Wu C,Fan X,Liu J,Tian Y,Cheng Y,Lu N,Zhang G
Thu Dec 22 00:00:00 EST 2022
A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4'-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells.
Cell stress & chaperones
Yang Y,Wu H,Zou X,Chen Y,He R,Jin Y,Zhou B,Ge C,Yang Y
Tue Nov 01 00:00:00 EDT 2022
Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure-Activity Relationships.
Molecules (Basel, Switzerland)
Zhang D,Li X,He X,Xing Y,Jiang B,Xiu Z,Bao Y,Dong Y
Sat Nov 12 00:00:00 EST 2022
HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats.
Molecular neurobiology
Chen J,Liu S,Wang X,Huang J,Phillips J,Ma D,Ouyang W,Tong J
Sat Oct 01 00:00:00 EDT 2022
LncRNA WEE2-AS1 Knockdown Inhibits the Proliferation, Migration and 3 Invasion of Glioma Cells via Regulating miR-29b-2-5p/TPM3 Axis.
Oncology research
Jia Z,Qian Z,Tang Y,Li X,Shi Y,Xin H,Fan Y,Wu H
Thu Apr 07 00:00:00 EDT 2022
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Animals : an open access journal from MDPI
Qi Y,Xue HL,Zheng YJ,Yin YF,Xu WL,Xu JH,Wu M,Chen L,Xu LX
Fri Dec 16 00:00:00 EST 2022
The Effect and Mechanism of Duodenal-Jejunal Bypass to Treat Type 2 Diabetes Mellitus in a Rat Model.
Obesity facts
Chen X,Zhang Q,Yang Q,Huang Z,Liao G,Wang Z
Thu May 19 00:00:00 EDT 2022
Adipose-derived stem cells alleviate liver injury induced by type 1 diabetes mellitus by inhibiting mitochondrial stress and attenuating inflammation.
Stem cell research & therapy
Hou Y,Ding W,Wu P,Liu C,Ding L,Liu J,Wang X
Fri Apr 01 00:00:00 EDT 2022
FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion.
Nature communications
Li S,Han S,Zhang Q,Zhu Y,Zhang H,Wang J,Zhao Y,Zhao J,Su L,Li L,Zhou D,Ye C,Feng XH,Liang T,Zhao B
Fri Jun 17 00:00:00 EDT 2022
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Microvascular research
Zhou YH,Tang YZ,Guo LY,Zheng LL,Zhang D,Yang CY,Wang W
Sat Jan 01 00:00:00 EST 2022
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Antioxidants (Basel, Switzerland)
Wu LL,Zhang Y,Li XZ,Du XL,Gao Y,Wang JX,Wang XL,Chen Q,Li YH,Zhu GQ,Tan X
Fri May 20 00:00:00 EDT 2022
Adrenomedullin is an Important Pathological Mediator in Progression of Chronic Neuropathic Pain.
Frontiers in bioscience (Landmark edition)
Wang C,Xue Y,Lu Q,Shi Y,Tang W,Wang D
Wed Jul 13 00:00:00 EDT 2022
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Journal of medicinal chemistry
Bian M,Fan R,Yang Z,Chen Y,Xu Z,Lu Y,Liu W
Thu Feb 10 00:00:00 EST 2022
Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer.
Oncology reports
Wang T,Liu J,Huang X,Zhang C,Shangguan M,Chen J,Wu S,Chen M,Yang Z,Zhao S
Tue Nov 01 00:00:00 EDT 2022
NEDD4 attenuates phosgene-induced acute lung injury through the inhibition of Notch1 activation.
Journal of cellular and molecular medicine
Shao Y,Jiang Z,He D,Shen J
Sun May 01 00:00:00 EDT 2022
A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model.
Emerging microbes & infections
Li D,Sun T,Tao L,Ji W,Zhu P,Liang R,Zhang Y,Chen S,Yang H,Jin Y,Duan G
Thu Dec 01 00:00:00 EST 2022
12/15-Lipoxygenase Regulation of Diabetic Cognitive Dysfunction Is Determined by Interfering with Inflammation and Cell Apoptosis.
International journal of molecular sciences
Chen Q,Zheng Q,Yang Y,Luo Y,Wang H,Li H,Yang L,Hu C,Zhang J,Li Y,Xia H,Chen Z,Ma J,Tian X,Yang J
Fri Aug 12 00:00:00 EDT 2022
Tetrandrine overcomes drug resistance mediated by bone marrow microenvironment by regulating the expression of P-glycoprotein in acute leukemia.
Hematology (Amsterdam, Netherlands)
Zhou X,Jin N,Chen B
Thu Dec 01 00:00:00 EST 2022
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
Phytotherapy research : PTR
Mao J,Zhan H,Meng F,Wang G,Huang D,Liao Z,Chen M
Tue Mar 01 00:00:00 EST 2022
Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang Y,Miao L,Peng Q,Fan X,Song W,Yang B,Zhang P,Liu G,Liu J
Sat Oct 01 00:00:00 EDT 2022
The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse.
EMBO reports
Wang W,Su L,Ji F,Zhang D,Wang Y,Zhao J,Jiao RD,Zhang M,Huang E,Jiang H,Zhang J,Jiao J
Thu Feb 03 00:00:00 EST 2022
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration.
ACS applied materials & interfaces
Xu Z,Liu Y,Ma R,Chen J,Qiu J,Du S,Li C,Wu Z,Yang X,Chen Z,Chen T
Wed Mar 30 00:00:00 EDT 2022
Proteomic and functional analyses of the periodic membrane skeleton in neurons.
Nature communications
Zhou R,Han B,Nowak R,Lu Y,Heller E,Xia C,Chishti AH,Fowler VM,Zhuang X
Thu Jun 09 00:00:00 EDT 2022
Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage.
Nature communications
Arakawa N,Ushiki A,Abe M,Matsuyama S,Saito Y,Kashiwada T,Horimasu Y,Gemma A,Tatsumi K,Hattori N,Tsushima K,Miyashita K,Saito K,Nakamura R,Toyoda T,Ogawa K,Sato M,Takamatsu K,Mori K,Nishiya T,Izumi T,Ohno Y,Saito Y,Hanaoka M
Tue Oct 04 00:00:00 EDT 2022
Effects of Low-Intensity Pulsed Ultrasound on the Migration and Homing of Human Amnion-Derived Mesenchymal Stem Cells to Ovaries in Rats With Premature Ovarian Insufficiency.
Cell transplantation
Ling L,Hou J,Wang Y,Shu H,Huang Y
Wed Oct 26 00:00:00 EDT 2022
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Antioxidants (Basel, Switzerland)
Tao W,Wang G,Pei X,Sun W,Wang M
Sun Jul 17 00:00:00 EDT 2022
PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis.
Journal of Cancer
Zheng X,Liu B,Liu X,Li P,Zhang P,Ye F,Zhao T,Kuang Y,Chen W,Jin X,Li Q
Tue Jan 25 00:00:00 EST 2022
The Effective Analysis for Blue Honeysuckle Extract in the Treatment of Hepatocellular Carcinoma.
Evidence-based complementary and alternative medicine : eCAM
Zhang CP,Li WH,Liu JR,Li GD,Zhang HP,Wei JF,Chen HS,Zhao JL,Wang YF,Lv Q,Liu M
Tue Oct 11 00:00:00 EDT 2022
Baicalein suppresses high glucose-induced inflammation and apoptosis in trophoblasts by targeting the miRNA-17-5p-Mfn1/2-NF-κB pathway.
Placenta
Li J,Wang Y,Wu T,Li S,Sun YN,Liu ZH
Fri Apr 01 00:00:00 EDT 2022
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
European journal of pharmacology
Huang Y,Chen S,Pang L,Feng Z,Su H,Zhu W,Wei J
Tue Feb 15 00:00:00 EST 2022
Interleukin-6-derived cancer-associated fibroblasts activate STAT3 pathway contributing to gemcitabine resistance in cholangiocarcinoma.
Frontiers in pharmacology
Kittirat Y,Suksawat M,Thongchot S,Padthaisong S,Phetcharaburanin J,Wangwiwatsin A,Klanrit P,Sangkhamanon S,Titapun A,Loilome W,Saya H,Namwat N
Tue Sep 13 00:00:00 EDT 2022
EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation.
Acta histochemica et cytochemica
Miyazaki S,Funamoto T,Sekimoto T,Kurogi S,Ohta T,Nagai T,Tajima T,Imasaka M,Yoshinobu K,Araki K,Araki M,Choijookhuu N,Hishikawa Y,Chosa E
Wed Jun 29 00:00:00 EDT 2022
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.
Cell reports
Sun Y,Zhang H,Meng J,Guo F,Ren D,Wu H,Jin X
Tue Aug 16 00:00:00 EDT 2022
Molecular and functional characterization of teleost-specific Interleukin-17N in yellow catfish (Pelteobagrus fulvidraco).
International journal of biological macromolecules
Zhou X,Jiang XX,Zhang GR,Ji W,Shi ZC,Ma XF,Wei KJ
Tue Nov 01 00:00:00 EDT 2022
Gasdermin D is involved in switching from apoptosis to pyroptosis in TLR4-mediated renal tubular epithelial cells injury in diabetic kidney disease.
Archives of biochemistry and biophysics
Yuan S,Wang Y,Li Z,Chen X,Song P,Chen A,Qu Z,Wen S,Liu H,Zhu X
Fri Sep 30 00:00:00 EDT 2022
Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy.
Theranostics
Shi Y,Liu Y,Huang J,Luo Z,Guo X,Jiang M,Li X,Lu Y,Liu X,Shan X,Luo L,You J
Tue May 17 00:00:00 EDT 2022
Candida albicans induces upregulation of programmed death ligand 1 in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Wang X,Zhao W,Zhang W,Wu S,Yan Z
Sun May 01 00:00:00 EDT 2022
Placental expression of estrogen-related receptor gamma is reduced in fetal growth restriction pregnancies and is mediated by hypoxia†.
Biology of reproduction
Zou Z,Harris LK,Forbes K,Heazell AEP
Mon Sep 12 00:00:00 EDT 2022
Mitigation Effects of Selenium Nanoparticles on Depression-Like Behavior Induced by Fluoride in Mice via the JAK2-STAT3 Pathway.
ACS applied materials & interfaces
Yang J,Li H,Hao Z,Jing X,Zhao Y,Cheng X,Ma H,Wang J,Wang J
Wed Jan 26 00:00:00 EST 2022
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
International journal of molecular sciences
Komatsu S,Tsutsui Y,Furuya T,Yamaguchi H,Hitachi K,Tsuchida K,Tani M
Thu Sep 08 00:00:00 EDT 2022
Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway.
Acta biochimica et biophysica Sinica
Guo C,Xu H,Zhou Y,Wu Z,Jiang B,Chen H,Lin D
Sun Dec 25 00:00:00 EST 2022
Downregulation of miR-30b-5p Facilitates Chondrocyte Hypertrophy and Apoptosis via Targeting Runx2 in Steroid-Induced Osteonecrosis of the Femoral Head.
International journal of molecular sciences
Lin L,Yu Y,Liu K,Jiang Y,Zhou Z
Sat Sep 24 00:00:00 EDT 2022
Protective effect of active components of Eucommia ulmoides leaves on gastric ulcers in rats: Involvement of the PI3K/Akt/NF-κB pathway.
Journal of food science
Gong M,Li Q,Guo H,Cui B,Liu Y,Wang P,Zhu H,Liu X,Dai L,Wang Z
Fri Jul 01 00:00:00 EDT 2022
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Theranostics
Yang L,Wu C,Parker E,Li Y,Dong Y,Tucker L,Brann DW,Lin HW,Zhang Q
Thu Apr 21 00:00:00 EDT 2022
ATRX-dependent SVCT2 mediates macrophage infiltration in the glioblastoma xenograft model.
Journal of neurophysiology
Shang J,Wang Y,Li Z,Jiang L,Bai Q,Zhang X,Xiao G,Zhang J
Sun May 01 00:00:00 EDT 2022
Tubuloside B, isolated from Cistanche tubulosa, a promising agent against M1 macrophage activation via synergistically targeting Mob1 and ERK1/2.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xiao L,Yao J,Miao Y,Ou B,Wang J,Huang Y,Zhou B,Ge L,Tian J,Zeng X
Thu Sep 01 00:00:00 EDT 2022
Transplantation of Human Umbilical Cord Mesenchymal Stem Cells-Derived Neural Stem Cells Pretreated with Neuregulin1β Ameliorate Cerebral Ischemic Reperfusion Injury in Rats.
Biomolecules
Zhai QY,Ren YQ,Ni QS,Song ZH,Ge KL,Guo YL
Thu Mar 10 00:00:00 EST 2022
Oxidative stress activates Ryr2-Ca2+ and apoptosis to promote PM2.5-induced heart injury of hyperlipidemia mice.
Ecotoxicology and environmental safety
Meng M,Jia R,Wei M,Meng X,Zhang X,Du R,Sun W,Wang L,Song L
Tue Mar 01 00:00:00 EST 2022
Hypoxia-inducible Factor Regulates Ten-eleven Translocated Methylcytosine Dioxygenase 1-c-Myc Binding Involved in Depression-like Behavior in Prenatal Hypoxia Offspring.
Neuroscience
Zeng H,Wei B,Liu J,Lu L,Li L,Wang B,Sun M
Sat Oct 15 00:00:00 EDT 2022
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Frontiers in bioengineering and biotechnology
Peng X,Ding C,Zhao Y,Hao M,Liu W,Yang M,Xiao F,Zheng Y
Sat Jul 23 00:00:00 EDT 2022
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Metabolic brain disease
Li F,Mao Q,Wang J,Zhang X,Lv X,Wu B,Yan T,Jia Y
Thu Dec 01 00:00:00 EST 2022
Puffball spores improve wound healing in a diabetic rat model.
Frontiers in endocrinology
He T,Sun P,Liu B,Wan S,Fang P,Chen J,Huang G,Min W
Tue Sep 20 00:00:00 EDT 2022
Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.
Pharmacology
Zhuo R,Cheng X,Luo L,Yang L,Zhao Y,Zhou Y,Peng L,Jin X,Cui L,Liu F,Yang L
Wed May 04 00:00:00 EDT 2022
Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout.
Genes & genomics
Geng YW,Zhang Z,Jin H,Da JL,Zhang K,Wang JQ,Guo YY,Zhang B,Li Y
Tue Feb 01 00:00:00 EST 2022
Systematic pan-cancer analysis identifies RALA as a tumor targeting immune therapeutic and prognostic marker.
Frontiers in immunology
Jin H,Qin S,He J,Xiao J,Li Q,Mao Y,Zhao L
Tue Dec 06 00:00:00 EST 2022
Venetoclax enhances NK cell killing sensitivity of AML cells through the NKG2D/NKG2DL activation pathway.
International immunopharmacology
Wu HY,Li KX,Pan WY,Guo MQ,Qiu DZ,He YJ,Li YH,Huang YX
Tue Mar 01 00:00:00 EST 2022
Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression.
Breast cancer research : BCR
Meng L,Chang S,Sang Y,Ding P,Wang L,Nan X,Xu R,Liu F,Gu L,Zheng Y,Li Z,Sang M
Tue Jan 04 00:00:00 EST 2022
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Frontiers in cell and developmental biology
Feng KL,Diao N,Zhou ZW,Fang CK,Wang JN,Zhang Y,Luo R,Zhong C
Sat Jul 16 00:00:00 EDT 2022
Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.
Frontiers in cardiovascular medicine
Zheng X,Zhong T,Yu F,Duan J,Tang Y,Liu Y,Li M,Sun D,Yin D
Fri Sep 30 00:00:00 EDT 2022
A positive feedback circuit comprising p21 and HIF-1α aggravates hypoxia-induced radioresistance of glioblastoma by promoting Glut1/LDHA-mediated glycolysis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jin X,Kuang Y,Li L,Li H,Zhao T,He Y,Di C,Kang J,Yuan L,Yu B,Li Q
Tue Mar 01 00:00:00 EST 2022
Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis.
Frontiers in neuroscience
Shao Y,Tian J,Yang Y,Hu Y,Zhu Y,Shu Q
Tue Aug 23 00:00:00 EDT 2022
Tumor microenvironment-related gene selenium-binding protein 1 (SELENBP1) is associated with immunotherapy efficacy and survival in colorectal cancer.
BMC gastroenterology
Zhu C,Wang S,Du Y,Dai Y,Huai Q,Li X,Du Y,Dai H,Yuan W,Yin S,Wang H
Mon Oct 17 00:00:00 EDT 2022
Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner.
Cellular signalling
Wang H,Wang J,Liu J,Wang Y,Xia G,Huang X
Sun May 01 00:00:00 EDT 2022
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
Molecular neurobiology
He Y,Chang Y,Peng Y,Zhu J,Liu K,Chen J,Wu Y,Ji Z,Lin Z,Wang S,Gupta S,Zang N,Pan S,Huang K
Sat Oct 01 00:00:00 EDT 2022
Host-induced gene silencing of PcCesA3 and PcOSBP1 confers resistance to Phytophthora capsici in Nicotiana benthamiana through NbDCL3 and NbDCL4 processed small interfering RNAs.
International journal of biological macromolecules
Wang Z,Gao X,Zhong S,Li Y,Shi M,Zhang B,Zhang S,Shen H,Liu X
Thu Dec 01 00:00:00 EST 2022
GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer via the Activation of ERK1/2 Signaling.
Frontiers in oncology
Wang L,Yang D,Zhang Y,Jiao Y
Sun Jul 31 00:00:00 EDT 2022
PIN1 protects auditory hair cells from senescence via autophagy.
PeerJ
Lv Z,Zhang Y,Cao H,Liu Q,Feng X,Yin H,Wang B
Fri Feb 10 00:00:00 EST 2023
Role of the cGAS-STING Pathway in Aging-related Endothelial Dysfunction.
Aging and disease
Yu H,Liao K,Hu Y,Lv D,Luo M,Liu Q,Huang L,Luo S
Thu Dec 01 00:00:00 EST 2022
The oral microbiome in young women at different stages of periodontitis: Prevotella dominant in stage III periodontitis.
Frontiers in cellular and infection microbiology
Zhao Y,Feng Y,Ye Q,Hu J,Feng Y,Ouyang Z,Zhao J,Chen Y,Tan L,Chen N,Dusenge MA,Su X,Guo Y
Tue Dec 20 00:00:00 EST 2022
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Molecules (Basel, Switzerland)
Ge S,Zhu X,Zhang C,Jia D,Shang W,Ding C,Yang J,Feng Y
Tue Dec 13 00:00
