|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||A synthetic peptide consisting of residues 8-17 (SGYEVHHQKL) of the amyloid beta-protein/amyloid A4 which is the same as aa 660-669 of human amyloid A4 / amyloid Beta protein precursor|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA5-11617 targets Amyloid Beta in IHC (P) applications and shows reactivity with Human samples.
The MA5-11617 immunogen is a synthetic peptide consisting of residues 8-17 (SGYEVHHQKL) of the amyloid beta-protein/amyloid A4 which is the same as aa 660-669 of human amyloid A4 / amyloid Beta protein precursor.
Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer's disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down's syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Distribution of the hematopoietic growth factor G-CSF and its receptor in the adult human brain with specific reference to Alzheimer's disease.
MA5-11617 was used in immunohistochemistry to investigate the protein expression of G-CSF and its receptor in the adult human brain
|Ridwan S,Bauer H,Frauenknecht K,Hefti K,von Pein H,Sommer CJ||Journal of anatomy (224:377)||2014|