Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 9 publications 9 publications |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Published species |
Human, Mouse, Zebrafish |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
cIAP1 Fusion Protein Ag15203 (1-350 aa encoded by BC016174) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.22 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
This BIRC2 antibody (10022-1-AP) can bind both full length (70 kDa) and cleaved form (60 kDa) of the protein.
Immunogen sequence: MHKTASQRL FPGPSYQNIK SIMEDSTILS DWTNSNKQKM KYDFSCELYR MSTYSTFPAG VPVSERSLAR AGFYYTGVND KVKCFCCGLM LDNWKLGDSP IQKHKQLYPS CSFIQNLVSA SLGSTSKNTS PMRNSFAHSL SPTLEHSSLF SGSYSSLSPN PLNSRAVEDI SSSRTNPYSY AMSTEEARFL TYHMWPLTFL SPSELARAGF YYIGPGDRVA CFACGGKLSN WEPKDDAMSE HRRHFPNCPF LENSLETLRF SISNLSMQTH AARMRTFMYW PSSVPVQPEQ LASAGFYYVG RNDDVKCFCC DGGLRCWESG DDPWVEHAKW FPRCEFLIRM KGQEFVDEIQ G (1-350 aa encoded by BC016174)
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis inhibitor 1; apoptosis inhibitor 2; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; Baculoviral IAP repeat-containing protein 2; C-IAP1; Cellular inhibitor of apoptosis 1; hIAP-2; IAP homolog B; IAP-2; Inhibitor of apoptosis protein 2; mIAP-2; mIAP2; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2
Gene Aliases: API1; Api2; AW146227; BIRC2; Birc3; c-IAP1; cIAP1; cIAP2; Hiap-2; HIAP1; HIAP2; IAP1; IAP2; mcIAP1; MIAP1; MIAP2; MIHB; MIHC; RNF48
UniProt ID: (Human) Q13490, (Mouse) Q62210
Entrez Gene ID: (Human) 329, (Mouse) 11797
Molecular Function:
protease inhibitor
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