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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal portion of the human protein (within residues 100-200).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:800-1:3200|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: Hela whole cell lysate; Jurkat whole cell lysate.
cIAP2 is an apoptotic suppressor. Apoptosis is activated by an array of stimuli including members of the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. These proteins contain a baculovirus IAP repeat (BIR) domain which interact with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form a heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). This complex may play a role in the inhibition of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AIP 2; API2; apoptosis inhibitor 2; baculoviral IAP repeat-containing 3; BIRC3 baculoviral IAP repeat containing 3; c-IAP2; cellular inhibitor of apoptosis 2; HAIP1; IAP homolog C; IAP-1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RING finger protein 49; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
AIP1; API2; BIRC3; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49