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Invitrogen
eIF2b beta Polyclonal Antibody
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Product Details
PA5-52217
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human eIF2b beta. Recombinant protein control fragment (Product #RP-88928).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PFCQGHEMAV NLSKAGIETT VMTDAAIFAV MSRVNKVIIG TKTILANGAL RAVTGTHTLA LAAKHHSTPL IVCAPMFKLS PQFPNEEDSF HKFVAPEEVL PFTEGDILEK VSVHCPVFDY VPPELITLFI SNIGGNAPSY IYRLMSELYH
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Target Information
eIF2b beta is the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2B GDP-GTP exchange factor subunit beta; eIF2B GDP-GTP exchange factor subunit beta; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; ORF; putative; S20I15; S20III15; similar to translation initiation factor eIF-2B beta subunit; translation initiation factor eIF-2B subunit beta; Translation initiation factor eIF2B subunit beta; unnamed protein product
Gene Aliases: AA409345; C85417; EIF-2Bbeta; EIF2B; EIF2B2; EIF2BB; EIF2Bbeta; VWM2
UniProt ID: (Human) P49770, (Mouse) Q99LD9
Entrez Gene ID: (Human) 8892, (Mouse) 217715, (Rat) 84005
ovarian follicle development
cytoplasmic translational initiation
translation
translational initiation
regulation of translational initiation
central nervous system development
response to heat
response to glucose
oligodendrocyte development
myelination
response to peptide hormone
animal organ development
T cell receptor signaling pathway
positive regulation of GTPase activity
cellular metabolic process
cellular response to stimulus
L-methionine biosynthetic process from methylthioadenosine
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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