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Bethyl Laboratories
eIF4G1/eIF4GI Polyclonal Antibody
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Product Details
A301-776A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 525 and 575 of human eukaryotic translation initiation factor 4 gamma, 1.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686A1451; eIF-4-gamma 1; EIF4-gamma; eIF4G isoform 1; eIF4G isoform 2; eIF4GI; eucaryotic translation initiation factor 4G; Eukaryotic translation initiation factor 4 gamma 1; OTTHUMP00000210577; OTTHUMP00000210586; OTTHUMP00000210587; OTTHUMP00000210588; OTTHUMP00000210595; OTTHUMP00000210602; OTTHUMP00000210603; p220; unnamed protein product
Gene Aliases: EIF-4G1; EIF4F; EIF4G; EIF4G1; EIF4GI; P220; PARK18
UniProt ID: (Human) Q04637
Entrez Gene ID: (Human) 1981
behavioral fear response
cap-dependent translational initiation
translation
translational initiation
regulation of translation
regulation of translational initiation
negative regulation of autophagy
neuron differentiation
positive regulation of cell growth
cellular response to nutrient levels
miRNA mediated inhibition of translation
positive regulation of translation in response to endoplasmic reticulum stress
positive regulation of neuron differentiation
positive regulation of protein metabolic process
regulation of cellular response to stress
energy homeostasis
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of protein localization to cell periphery
positive regulation of eukaryotic translation initiation factor 4F complex assembly
regulation of presynapse assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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