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Bioss
hCG receptor Polyclonal Antibody
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Product Details
BS-0984R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse LHCGR, amino acids 501-600.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HCG receptor; LH receptor; LH/CG-R; LSH-R; Luteinizing hormone receptor; Lutropin receptor; Lutropin-choriogonadotropic hormone receptor
Gene Aliases: Gpcr19-rs1; LH-R; LH/CG-R; Lhcgr; Lhr; LSH-R; LSHR
UniProt ID: (Rat) P16235, (Mouse) P30730
Entrez Gene ID: (Rat) 25477, (Mouse) 16867
luteinizing hormone receptor activity
G-protein coupled peptide receptor activity
peptide hormone binding
choriogonadotropin hormone receptor activity
choriogonadotropin hormone binding
identical protein binding
protein homodimerization activity
ATPase binding
signal transducer activity
G-protein coupled receptor activity
protein-hormone receptor activity
G-protein coupled receptor
ovarian follicle development
protein targeting to lysosome
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
spermatogenesis
central nervous system development
male gonad development
female gonad development
hormone-mediated signaling pathway
positive regulation of calcium ion transport into cytosol
ovulation cycle process
positive regulation of inositol trisphosphate biosynthetic process
response to drug
luteinizing hormone signaling pathway
positive regulation of cAMP-mediated signaling
development of secondary male sexual characteristics
positive regulation of hormone biosynthetic process
arachidonic acid secretion
regulation of steroid biosynthetic process
positive regulation of calcium-mediated signaling
cognition
positive regulation of release of sequestered calcium ion into cytosol
uterus development
cellular response to gonadotropin stimulus
seminiferous tubule development
regulation of steroid hormone biosynthetic process
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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