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|Tested species reactivity||Human, Mouse, Rabbit, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from C-ternimal of mouse iNOS|
|Storage buffer||PBS, pH 7.6, with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1-3 µg/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
PA5-16855 targets iNOS in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-16855 immunogen is a synthetic peptide derived from C-ternimal of mouse iNOS.
NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti-tumor and anti-pathogenic activities. Inducible NOS (iNOS) or macrophage NOS (mNOS) is a calcium/calmodulin independent and is expressed in activated macrophages and stimulated glial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Alpha-melanocyte stimulating hormone ameliorates disease activity in an induced murine lupus-like model.
PA5-16855 was used in immunohistochemistry to study the beneficial effects of alpha-MSH in a murine model of lupus
|Botte DA,Noronha IL,Malheiros DM,Peixoto TV,de Mello SB||Clinical and experimental immunology (177:381)||2014|
hepatocyte NOS; inducible; inducible nitric oxide synthase; inducible NO synthase; inducible NOS; MAC-NOS; macrophage; macrophage NOS; nitric oxide synthase; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS type II; NOS, type II; peptidyl-cysteine S-nitrosylase NOS2
HEP-NOS; i-NOS; INOS; Inosl; NOS; Nos-2; NOS-II; NOS2; NOS2A