In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset (100%) Rat, Dog, Panda, Rabbit (83%).
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
Protein Aliases: glutamate receptor; glutamate receptor, metabotropic 6; Metabotropic glutamate receptor 6; mGluR6
Gene Aliases: CSNB1B; GPRC1F; GRM6; mGlu6; MGLUR6
UniProt ID: (Human) O15303
Entrez Gene ID: (Human) 2916
Molecular Function: G-protein coupled receptor