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Proteintech
p115/USO1 Polyclonal Antibody
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Product Details
13509-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
p115, USO1 Fusion Protein Ag4431 (660-961 aa encoded by BC032654)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EQDLQLEEL RQQVSTLKCQ NEQLQTAVTQ QVSQIQQHKD QYNLLKIQLG KDNQHQGSYS EGAQMNGIQP EEIGRLREEI EELKRNQELL QSQLTEKDSM IENMKSSQTS GTNEQSSAIV SARDSEQVAE LKQELATLKS QLNSQSVEIT KLQTEKQELL QKTEAFAKSV EVQGETETII ATKTTDVEGR LSALLQETKE LKNEIKALSE ERTAIKEQLD SSNSTIAILQ TEKDKLELEI TDSKKEQDDL LVLLADQDQK ILSLKNKLKD LGHPVEEEDE LESGDQEDED DESEDPGKDL DHI (660-961 aa encoded by BC032654)
Target Information
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: General vesicular transport factor p115; Protein USO1 homolog; TAP; transcytosis associated protein; transcytosis associated protein p115; Transcytosis-associated protein; unnamed protein product; USO1 homolog, vesicle docking protein; USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein p115; vesicle docking protein, 115 kDa; Vesicle-docking protein
Gene Aliases: 115kDa; P115; TAP; USO1; VDP
UniProt ID: (Human) O60763, (Mouse) Q9Z1Z0, (Rat) P41542
Entrez Gene ID: (Human) 8615, (Mouse) 56041, (Rat) 56042
intracellular protein transport
ER to Golgi vesicle-mediated transport
Golgi organization
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
secretory granule localization
transcytosis
Golgi vesicle transport
Golgi vesicle docking
vesicle fusion with Golgi apparatus
membrane fusion
regulation of cellular response to insulin stimulus
transport
intra-Golgi vesicle-mediated transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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