PA5-16539 targets p57Kip2 in IHC (P) applications and shows reactivity with mouse, Bovine, and Human samples.
The PA5-16539 immunogen is a synthetic peptide from human p57Kip2 protein.
This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
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Protein Aliases: Cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); Cyclin-dependent kinase inhibitor p57; IMAGE; p57 Kip2; p57Kip2
Gene Aliases: AL024410; BWCR; BWS; CDKI; CDKN1C; KIP2; p57; p57(kip2); p57Kip2; WBS