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Invitrogen
p8 Polyclonal Antibody
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Product Details
PA5149671
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NUPR1
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TFPPATSAPQ QPPGPEDEDS SLDESDLYSL AHSYLGGGGR KGRTKREAAA NTNRPSPGGH ERKLVTKLQN SERKK
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.
Target Information
The human p8 gene encodes a nuclear protein with strong mitogenic activity, which is expressed in the pancreas in response to acute pancreatitis. Response to TNF alpha and staurosporine-induced apoptosis is not modified by p8 expression. However, cells expressing p8 grow significantly and more rapidly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60B8AG; CAGA; Candidate of metastasis 1; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; Nuclear protein 1; nuclear protein, transcriptional regulator, 1; nuclear transcriptional regulator protein 1; P8; Protein p8; unnamed protein product
Gene Aliases: COM1; NUPR1; P8
UniProt ID: (Human) O60356
Entrez Gene ID: (Human) 26471
acute inflammatory response
negative regulation of cell proliferation
male gonad development
response to toxic substance
regulation of autophagy
negative regulation of autophagy
negative regulation of cardiac muscle cell apoptotic process
skeletal muscle cell differentiation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
fibroblast apoptotic process
negative regulation of cell cycle
positive regulation of cell cycle
negative regulation of glycolytic process
positive regulation of transcription, DNA-templated
fibroblast proliferation
negative regulation of fibroblast proliferation
negative regulation of epithelial cell proliferation
negative regulation of programmed necrotic cell death
protein-containing complex assembly
positive regulation of neuroinflammatory response
positive regulation of proteasomal protein catabolic process
negative regulation of autophagosome assembly
positive regulation of oxidative phosphorylation
negative regulation of epithelial cell apoptotic process
negative regulation of type B pancreatic cell proliferation
regulation of response to endoplasmic reticulum stress
regulation of female gonad development
positive regulation of fibroblast apoptotic process
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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