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Invitrogen
p8 Polyclonal Antibody
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Product Details
PA5149671
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NUPR1
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TFPPATSAPQ QPPGPEDEDS SLDESDLYSL AHSYLGGGGR KGRTKREAAA NTNRPSPGGH ERKLVTKLQN SERKK
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.
Target Information
The human p8 gene encodes a nuclear protein with strong mitogenic activity, which is expressed in the pancreas in response to acute pancreatitis. Response to TNF alpha and staurosporine-induced apoptosis is not modified by p8 expression. However, cells expressing p8 grow significantly and more rapidly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60B8AG; CAGA; Candidate of metastasis 1; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; Nuclear protein 1; nuclear protein, transcriptional regulator, 1; nuclear transcriptional regulator protein 1; Protein p8
Gene Aliases: COM1; NUPR1; P8
UniProt ID: (Human) O60356
Entrez Gene ID: (Human) 26471
acute inflammatory response
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein complex assembly
protein acetylation
male gonad development
response to toxic substance
cell growth
positive regulation of protein modification process
skeletal muscle cell differentiation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
negative regulation of cell cycle
negative regulation of fibroblast proliferation
regulation of female gonad development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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