PA5-29229 targets pro-EGF in IHC (P) application and shows reactivity with Human samples.
The PA5-29229 immunogen is recombinant fragment corresponding to a region within amino acids 495 and 774 of Human pro-EGF.
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Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.
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Protein Aliases: beta-urogastrone; EGF; Epidermal growth factor; HOMG4; Pro-epidermal growth factor; URG; Urogastrone
Gene Aliases: EGF; HOMG4; URG
UniProt ID: (Human) P01133
Entrez Gene ID: (Human) 1950