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Fabgennix
proANP Polyclonal Antibody
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Product Details
PANP-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 100-150 on human proANP protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANPRC; atrial natriuretic factor; Atrial natriuretic factor prohormone; atrial natriuretic peptide; Atrial natriuretic peptide prohormone; Atrial natriuretic peptide receptor 3; Atriopeptigen; atriopeptin; Cardiodilatin; cardiodilatin-related peptide; cardionatrin; CDD; natriuretic peptide precursor A; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor A variant NPPA-M1; natriuretic peptide precursor A variant NPPA-M2; natriuretic peptide precursor A variant NPPA-M3; natriuretic peptide precursor type A; Natriuretic peptides A; NPR3; preproANF; preproANP; preprocardiodilatin-atrial natriuretic factor; preproCDD-ANF; prepronatiodilatin (PND); prepronatriodilatin; proANF; proANP
Gene Aliases: ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; NPPA; PND; RATANF
UniProt ID: (Human) P01160, (Rat) P01161, (Mouse) P05125
Entrez Gene ID: (Human) 4878, (Rat) 24602, (Mouse) 230899
response to hypoxia
system process
negative regulation of systemic arterial blood pressure
cardiac conduction system development
aortic valve morphogenesis
cGMP biosynthetic process
protein folding
receptor guanylyl cyclase signaling pathway
neuropeptide signaling pathway
female pregnancy
regulation of blood pressure
positive regulation of heart rate
positive regulation of cGMP-mediated signaling
cardiac muscle hypertrophy in response to stress
cGMP-mediated signaling
negative regulation of cell growth
response to insulin
response to muscle stretch
sodium ion export from cell
negative regulation of epidermal growth factor receptor signaling pathway
vasodilation
regulation of vascular permeability
negative regulation of JUN kinase activity
negative regulation of blood pressure
regulation of atrial cardiac muscle cell membrane repolarization
positive regulation of cardiac muscle contraction
cell growth involved in cardiac muscle cell development
cellular response to hydrogen peroxide
cellular response to mechanical stimulus
negative regulation of canonical Wnt signaling pathway
regulation of blood vessel diameter
synaptic signaling via neuropeptide
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
positive regulation of potassium ion export across plasma membrane
negative regulation of collecting lymphatic vessel constriction
cellular response to angiotensin
response to 3-methylcholanthrene
heart development
regulation of body fluid levels
regulation of blood vessel size
multicellular organismal water homeostasis
regulation of high voltage-gated calcium channel activity
positive regulation of delayed rectifier potassium channel activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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