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Fabgennix
xCT Polyclonal Antibody
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Product Details
SLC7A11-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids within region 275-325 on human SLC7A11 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
proprietary buffer with 30% glycerol
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; cysteine/glutamate transporter; Cystine/glutamate transporter; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; Solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; Subtle gray protein; xCT
Gene Aliases: 9930009M05Rik; AI451155; CCBR1; SLC7A11; sut; xCT
UniProt ID: (Human) Q9UPY5, (Mouse) Q9WTR6
Entrez Gene ID: (Human) 23657, (Mouse) 26570, (Rat) 310392
amino acid transmembrane transport
amino acid transport
response to oxidative stress
brain development
response to toxic substance
response to nicotine
leukocyte migration
lens fiber cell differentiation
platelet aggregation
L-glutamate transmembrane transport
transport
neutral amino acid transport
modified amino acid transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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