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Human ALK-6/BMPR-IB quantitates human ALK-6/BMPR-IB in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ALK-6/BMPR-IB.
BMPR1B (also known as ALK6, CDw293) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2. BMPR1B is mainly involved in the endochondral bone formation and embryogenesis. BMPR1B expressed in normal and cancerous prostate tissues and used in the endocrine therapy that given to the prostate cancer patients. BMPR1B receptor trafficking also play a significant role in FOP pathogenesis and used in human T-cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ALK-6, ALK6, AMDD, BDA1D, BDA2, BMPR1B, CDw293
Gene ID : (Human) 658
Gene symbol : BMPR1B
Protein Aliases : activin receptor-like kinase 6, BMP type-1B receptor, BMPR-1B, bone morphogenetic protein receptor type IB, Bone morphogenetic protein receptor type-1B, bone morphogenetic protein receptor, type IB, CDw293, serine/threonine receptor kinase
UniProt ID (Human) O00238
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