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Invitrogen
Human IFN alpha/beta R2 ELISA Kit
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Product Specifications
Analytical sensitivity
0.16 ng/mL
Assay range
0.16-40 ng/mL
Sample type/volume
Supernatant
50 µL
Plasma
50 µL
Serum
50 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
<12%
Intraassay CV
<10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Shipping conditions
Wet ice
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Protein name
IFNAR2
Species (tested)
Human
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
Human IFN alpha/beta R2 quantitates human IFN alpha/beta R2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IFN alpha/beta R2.
Target information
The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : IFN-alpha-REC, IFN-R, IFNABR, IFNAR2, IFNARB, IMD45
Gene ID : (Human) 3455
Gene symbol : IFNAR2
Protein Aliases : human interferon alpha/beta receptor, IFN alpha/betaRbeta, IFN R2, IFNalpha/beta R2, IFNalpha/betaR2, IFN-alpha/betaR2, IFN-alpha/betaRbeta, IFNalpha/beta-Rbeta, IFNR2, IFN-alpha/beta receptor 2, IFN-R-2, interferon (alpha, beta and omega) receptor 2, Interferon alpha binding protein, Interferon alpha/beta receptor 2, interferon-alpha/beta receptor beta chain, Type I interferon receptor 2
UniProt ID (Human) P48551
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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