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Human IGFBP-rp1/IGFBP-7 quantitates human IGFBP-rp1/IGFBP-7 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IGFBP-rp1/IGFBP-7.
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBP7, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF
Gene ID : (Human) 3490
Gene symbol : IGFBP7
Protein Aliases : angiomodulin, IBP-7, IGF-binding protein 7, IGFBP-rP1, insulin-like growth factor binding protein 7, Insulin-like growth factor-binding protein 7, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, TAF, Tumor-derived adhesion factor
UniProt ID (Human) Q16270
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