Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Human Lp-PLA2/PLA2G7/PAF-AH quantitates human Lp-PLA2/PLA2G7/PAF-AH in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Lp-PLA2/PLA2G7/PAF-AH.
Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL-associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : LDL-PLA2, LP-PLA2, PAFAD, PAFAH, PLA2G7
Gene ID : (Human) 7941
Gene symbol : PLA2G7
Protein Aliases : 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA(2), lipoprotein-associated phospholipase A2, PAF 2-acylhydrolase, PAF acetylhydrolase, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), Platelet-activating factor acetylhydrolase
UniProt ID (Human) Q13093
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