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Invitrogen
Human Neuropilin 1 Rapid ELISA Kit
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Product Specifications
Analytical sensitivity
0.47 ng/mL
Assay range
0.78-50
Sample type/volume
Plasma
50 µL
Serum
50 µL
Hands-on time
15 min
Time-to-result
1 hr 30 min
Homogenous (no wash)
No
Interassay CV
<10%
Intraassay CV
<10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated 96 well plate, Standard, HRP Conjugate, Standard & Sample Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
Shipping conditions
Wet ice
Storage
Refer to product documentation for component specific storage temperature.
Protein name
Neuropilin 1 (CD304)
Species (tested)
Human
Assay kit format
Rapid ELISA Kit
Detector antibody conjugate
HRP
Label or dye
Unconjugated
About This Kit
The Human Neuropilin 1 Rapid ELISA Kit quantitates Neuropilin 1 (CD304) in serum and plasma
Target information
Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain. Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors. Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system. This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis. Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : BDCA4, CD304, NP1, NRP, NRP1, VEGF165R
Gene ID : (Human) 8829
Gene symbol : NRP1
Protein Aliases : alternatively spliced, lacks exon 16, CD304, Neuropilin, Neuropilin1, NRP 1, sNRP 1, sNRP1, soluble NRP 1, soluble NRP1, Neuropilin-1, receptor for VEGF165 and semaphorins class 3, transmembrane receptor, unnamed protein product, Vascular endothelial cell growth factor 165 receptor, VEGF 165 receptor
UniProt ID (Human) O14786
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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