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Invitrogen
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Human OX40L quantitates human OX40L in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human OX40L.
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CD134L, CD252, GP34, OX-40L, OX4OL, TNFSF4, TNLG2B, TXGP1
Gene ID : (Human) 7292
Gene symbol : TNFSF4
Protein Aliases : CD134 ligand, CD252, Glycoprotein Gp34, OX40 antigen ligand, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, tax-transcriptionally activated glycoprotein 1 (34kD), tumor necrosis factor (ligand) superfamily member 4, tumor necrosis factor ligand 2B, Tumor necrosis factor ligand superfamily member 4
UniProt ID (Human) P23510
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