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The Human Osteoprotegerin Rapid ELISA Kit quantitates TNFRSF11B in serum and plasma
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : OCIF, OPG, PDB5, TNFRSF11B, TR1
Gene ID : (Human) 4982
Gene symbol : TNFRSF11B
Protein Aliases : MGC29565, soluble OPG, soluble Osteoprotegerin, sOPG, OPG, Osteoclastogenesis inhibitory factor, Osteoprotegerin, Tumor necrosis factor receptor superfamily member 11B, tumor necrosis factor receptor superfamily, member 11b, unnamed protein product
UniProt ID (Human) O00300
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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