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Human SQSTM1 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human P62 in serum, plasma, and cell culture supernatants.
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : A170, FTDALS3, ORCA, OSIL, p60, p62, p62B, PDB3, SQSTM1, ZIP3
Gene ID : (Human) 8878
Gene symbol : SQSTM1
Protein Aliases : EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, oxidative stress induced like, p62, phosphotyrosine independent ligand for the Lck SH2 domain p62, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Sequestosome-1, Ubiquitin-binding protein p62
UniProt ID (Human) Q13501
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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