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Invitrogen
Mouse 4-1BB Ligand ELISA Kit
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Product Specifications
Analytical sensitivity
0.75 ng/mL
Assay range
0.75-200 ng/mL
Sample type/volume
Serum
100 µL
Plasma
100 µL
Supernatant
100 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
12%
Intraassay CV
10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated microwell plate
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Shipping conditions
Wet ice
Storage
-20°C
Protein name
4-1BBL (CD137L)
Species (tested)
Mouse
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
Mouse 4-1BB Ligand ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of mouse 4-1BB Ligand (TNFSF9) in serum, plasma, and cell culture supernatants.
Target information
CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation. Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes. Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity. CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma). CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : 4-1BB-L, 4-1BBL, AI848817, Cd137l, Cd157l, Ly63l, Tnfsf9
Gene ID : (Mouse) 21950
Gene symbol : Tnfsf9
Protein Aliases : 4 1 BB Ligand, 4 1 BBL, 41BB Ligand, 41BBL, CD 137 Ligand, CD 137L, CD137 Ligand, CDw137L, TNFRSF9, 4-1BB ligand, 4-1BBL, Tumor necrosis factor ligand superfamily member 9
UniProt ID (Mouse) P41274
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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