LinkSēq™ Blood Genotyping
Real-Time PCR for ABO and HPA Genotyping
Fast, Easy, Comprehensive Molecular Antigen Typing using real-time PCR
LinkSēq real-time PCR molecular antigen typing overcomes the major challenges of molecular typing by increasing laboratory productivity, reducing turnaround time, and predicting phenotypes for many antigens given the common variants for those antigens.
LinkSēq™ Portfolio for Blood Genotyping
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Why Choose LinkSēq for Blood Genotyping?
More Antigens, No Chips, No Gels, No Wait
Simplicity
Fast workflow with little hands-on effort
- 10 minutes hands-on time—simply add your DNA to the pre-aliquoted buffer/enzyme mix, add to the tray, seal, and you are done
Easy data analysis via SureTyper™ Blood
- Automatically calls genotype and predicts phenotypes based on ISBT allele database and proprietary algorithm—in seconds
- Simple data drill-down tools
- Easy to use, intuitive interface
Confidence
Accurate real-time PCR
- Allele-specific amplification combined with SYBR® Green to detect PCR products without chips or gels
Robust contamination protection
- Samples are handled only once and then sealed in reaction trays
- Increased sample protection as amplified PCR products remain sealed
Easy integration with data management systems via XML export
Flexibility
- Broad instrument compatibility
- High throughput to a single sample
Fast Turnaround
- DNA sample to results in 90 minutes
- Just 10 minutes of hands-on time
LinkSēq – Fast Workflow with Minimal Hands-on Time
90 minutes to results
Add
Hands On: 10 min
Amplify
Hands off: 70 min
Analyze
Automated: 10 min
LinkSēq™ ABO Genotyping and Subgrouping
ABO alleles encode the enzyme Glycosyltransferase. Many A subgroups involve a weakly expressed A antigen, which can cause discordant serological reactions in forward and reverse typing. Our ABO products offers a better solution to research these alleles by separating A1 from non-A1, B from B3, Bweak and Bel, and much more.
Example of results provided in our SureTyper Blood Software
Generate clear results in seconds
View raw data
Coverage Includes:
- A, B, AB, cisAB, O
- A subgroups: A1 or non-A1, ie, A2, A3, Aweak, Ael or Am
- B subgroups: B, B3, Bweak or Bel
- O subgroups: O1, O2
- Possible Bombay phenotype
LinkSeq™ HPA Genotyping
Human Platelet Antigens (HPA) are glycoproteins expressed on platelet membranes. Our HPA assays are designed to target both the a and b alleles for HPA-1 through HPA-11, and HPA-15.
Example of HPA Results providing in the SureTyper Blood Software
Generate clear results in seconds
View raw data
Coverage Includes:
- HPA-1 through HPA-11
- HPA-15
For Research Use Only. Not for use in diagnostic procedures.
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