Product References
Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression.
PloS one
Goldstein JD,Burlion A,Zaragoza B,Sendeyo K,Polansky JK,Huehn J,Piaggio E,Salomon BL,Marodon G
RM6004 was used in flow cytometry to explore the role of the JAK/STAT pathway in controlling Foxp3 in regulatory T cells
Thu Aug 25 00:00:00 EDT 2016
Glibenclamide Prevents Diabetes in NOD Mice.
PloS one
Lamprianou S,Gysemans C,Bou Saab J,Pontes H,Mathieu C,Meda P
RM6004 was used in flow cytometry to explore if the anti-diabetic sulphonylurea glibenclamide protects insulin-producing cells against conditions mimicking those expected at the onset of type 1 diabetes
Tue Jul 18 00:00:00 EDT 2017
ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection.
European journal of immunology
Redpath SA,van der Werf N,Cervera AM,MacDonald AS,Gray D,Maizels RM,Taylor MD
RM6004 was used in flow cytometry to identify factors that promote the development of Foxp3(+) T regulatory cells during helminth infections
Fri Mar 01 00:00:00 EST 2013
CD4+ Foxp3+ regulatory T cells mediate Toxoplasma gondii-induced T-cell suppression through an IL-2-related mechanism but independently of IL-10.
European journal of immunology
Tenorio EP,Fernández J,Castellanos C,Olguín JE,Saavedra R
RM6004 was used in Flow cytometry/Cell sorting to study the role of Treg cells in Toxoplasma gondii induced suppression.
Thu Dec 01 00:00:00 EST 2011
Antigen dose-dependent suppression of murine IgE responses is mediated by CD4(-)CD8(-) double-negative T cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Barwig C,Raker V,Montermann E,Grabbe S,Reske-Kunz AB,Sudowe S
RM6004 was used in flow cytometry to report that the IgE response against protein antigens is influenced by the antigen dose
Tue Jun 01 00:00:00 EDT 2010
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
RM6004 was used in flow cytometry to determine the roles of c-Myb during lymphocyte development
Sun Nov 01 00:00:00 EDT 2009
Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells.
Nature medicine
Ding Y,Shen S,Lino AC,Curotto de Lafaille MA,Lafaille JJ
RM6004 was used in Flow cytometry/Cell sorting to discover beta-catenin stabilization causes enhanced survival of existing regulatory T cells, and unresponsiveness in precursors of T effector cells.
Fri Feb 01 00:00:00 EST 2008
Role for CTLA-4 but not CD25+ T cells during Schistosoma mansoni infection of mice.
Parasite immunology
Walsh CM,Smith P,Fallon PG
RM6004 was used in flow cytometry to study the regulation of CTLA-4+ and CD25+ T cells in schistosome infection
Fri Jun 01 00:00:00 EDT 2007
Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer.
Journal of immunology (Baltimore, Md. : 1950)
Sfondrini L,Rossini A,Besusso D,Merlo A,Tagliabue E,Mènard S,Balsari A
RM6004 was used in flow cytometry to evaluate the antitumor effects of purified Salmonella typhimurium flagellin
Thu Jun 01 00:00:00 EDT 2006
Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Cassan C,Piaggio E,Zappulla JP,Mars LT,Couturier N,Bucciarelli F,Desbois S,Bauer J,Gonzalez-Dunia D,Liblau RS
RM6004 was used in flow cytometry to study a reduction of the number of splenic Foxp3+ regulatory T cells by pertussis toxin
Tue Aug 01 00:00:00 EDT 2006
Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract.
Journal of virology
Gray PM,Arimilli S,Palmer EM,Parks GD,Alexander-Miller MA
RM6004 was used in flow cytometry to use infection of the respiratory tract with paramyxovirus simian virus 5 to study lung CD8+ T cell responses
Tue Mar 01 00:00:00 EST 2005
In vitro study of immunosuppressive effect of apoptotic cells.
Journal of Zhejiang University. Science. B
Zhang WJ,Zheng SS
RM6004 was used in flow cytometry to investigate how apoptotic cells alter macrophage and T cell functions
Thu Sep 01 00:00:00 EDT 2005
Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice.
Journal of cell science
Sangaletti S,Gioiosa L,Guiducci C,Rotta G,Rescigno M,Stoppacciaro A,Chiodoni C,Colombo MP
RM6004 was used in flow cytometry to compare Langerhans cell and dendritic-cell migration and their impact on T-cell priming in SPARC-null and -sufficient mice
Mon Aug 15 00:00:00 EDT 2005
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.
Journal of immunology (Baltimore, Md. : 1950)
Mangan NE,Fallon RE,Smith P,van Rooijen N,McKenzie AN,Fallon PG
RM6004 was used in flow cytometry to test if infection with Schistosoma mansoni alters the susceptibility of mice to anaphylaxis
Mon Nov 15 00:00:00 EST 2004
Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains.
European journal of immunology
Kawamoto H,Ohmura K,Fujimoto S,Lu M,Ikawa T,Katsura Y
RM6004 was used in flow cytometry to assess the proliferative potential of thymic progenitors that are T cell lineage restricted.
Sat Mar 01 00:00:00 EST 2003
Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit.
Journal of immunology (Baltimore, Md. : 1950)
Cabatingan MS,Schmidt MR,Sen R,Woodland RT
RM6004 was used in flow cytometry to investigate homeostatic B cell proliferation.
Sun Dec 15 00:00:00 EST 2002
Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain.
Journal of immunology (Baltimore, Md. : 1950)
Wu TS,Lee JM,Lai YG,Hsu JC,Tsai CY,Lee YH,Liao NS
RM6004 was used in flow cytometry to study loss of CD8+ cells in IL-15Ralpha(-/-) mice.
Tue Jan 15 00:00:00 EST 2002
Immunosuppression during acute Trypanosoma cruzi infection: involvement of Ly6G (Gr1(+))CD11b(+ )immature myeloid suppressor cells.
International immunology
Goñi O,Alcaide P,Fresno M
RM6004 was used in flow cytometry to elucidate the immunosuppressive mechanism that occurs during T. cruzi infection.
Tue Oct 01 00:00:00 EDT 2002
Candida albicans infection enhances immunosuppression induced by cyclophosphamide by selective priming of suppressive myeloid progenitors for NO production.
Cellular immunology
Angulo I,Jiménez-Díaz MB,García-Bustos JF,Gargallo D,de las Heras FG,Muñoz-Fernández MA,Fresno M
RM6004 was used in flow cytometry to examine the T cell responses in cyclophosphamide-treated mice after systemic infection with Candida albicans.
Wed Feb 05 00:00:00 EST 2003
Severe inflammatory arthritis and lymphadenopathy in the absence of TNF.
The Journal of clinical investigation
Campbell IK,O'Donnell K,Lawlor KE,Wicks IP
RM6004 was used in flow cytometry to examine the impact of TNF on rheumatoid arthritis.
Fri Jun 01 00:00:00 EDT 2001
Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency.
European journal of immunology
Attinger A,MacDonald HR,Acha-Orbea H
RM6004 was used in flow cytometry to report that the lymphoid environment limits T cell proliferation in response to high superantigen levels.
Thu Mar 01 00:00:00 EST 2001
An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation.
Journal of immunology (Baltimore, Md. : 1950)
Kovalev GI,Franklin DS,Coffield VM,Xiong Y,Su L
RM6004 was used in flow cytometry to report that the inhibitor, p18(INK4c), modulates TCR-mediated T cell proliferation.
Sat Sep 15 00:00:00 EDT 2001
Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells.
International immunology
Izeradjene K,Revillard JP,Genestier L
RM6004 was used in flow cytometry to assess the effects of folate analogues on superantigen-reactive peripheral T cells in vivo.
Mon Jan 01 00:00:00 EST 2001
Loss of c-kit accompanies B-lineage commitment and acquisition of CD45R by most murine B-lymphocyte precursors.
Blood
Payne KJ,Medina KL,Kincade PW
RM6004 was used in flow cytometry to identify new markers for isolating B-lineage precursors.
Thu Jul 15 00:00:00 EDT 1999
Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes.
The Journal of experimental medicine
Kang J,Coles M,Raulet DH
RM6004 was used in flow cytometry to determine the role of IL-7R signaling in gamma/delta T cell development.
Mon Oct 04 00:00:00 EDT 1999
Oral administration of the bacterial superantigen staphylococcal enterotoxin B induces activation and cytokine production by T cells in murine gut-associated lymphoid tissue.
Journal of immunology (Baltimore, Md. : 1950)
Spiekermann GM,Nagler-Anderson C
RM6004 was used in flow cytometry to compare gut and peripheral T cell responses after staphylococcal enterotoxin treatment.
Tue Dec 01 00:00:00 EST 1998
Homeostasis limits the development of mature CD8+ but not CD4+ thymocytes.
Journal of immunology (Baltimore, Md. : 1950)
van Meerwijk JP,Marguerat S,MacDonald HR
RM6004 was used in flow cytometry to identify mechanisms that regulate the generation and maturation of thymocytes.
Sun Mar 15 00:00:00 EST 1998
Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4.
International immunology
Liu L,Rich BE,Inobe J,Chen W,Weiner HL
RM6004 was used in flow cytometry to identify the initial source of IL-4 in early immune responses.
Sat Aug 01 00:00:00 EDT 1998
Clonal proliferation and cytokine requirement of murine progenitors for natural killer cells.
Blood
Aiba Y,Hirayama F,Ogawa M
RM6004 was used in flow cytometry to elucidate the pathway and cytokine regulation of NK cell development in vitro.
Sun Jun 01 00:00:00 EDT 1997
Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes.
Nature
Lowenthal JW,Zubler RH,Nabholz M,MacDonald HR
RM6004 was used in flow cytometry to compare IL-2 receptor expression on activated B and T cells
Mon Aug 19 00:00:00 EDT 1985