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NeoBiotechnologies
Collagen II (COL2A1) Recombinant Rabbit Monoclonal Antibody (COL2A1/8810R)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
1280-RBM4-P0
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
COL2A1/8810R
Immunogen
bovine collagen type II (CII).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Protein A/G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: Human cartilage lung or eye.
Cellular Location: Secreted. Extracellular matrix.
Target Information
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-1 type II collagen; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; CGA; chondrocalcin; COL2A1; Collagen 2; collagen II, alpha-1 polypeptide; collagen, type II, alpha 1; MGC131516; unnamed protein product
Gene Aliases: ACG2; ANFH; ANFH1; AOM; COL11A3; EDMMD; LCPD; OSCDP; PLSDT; SEDC; SEDSTN; SEMDSTWK; SMDALG; STL1; VPED
UniProt ID: (Human) P02458
Entrez Gene ID: (Human) 1280
skeletal system development
ossification
chondrocyte differentiation
central nervous system development
visual perception
sensory perception of sound
collagen fibril organization
notochord development
animal organ development
skeletal system morphogenesis
system development
cartilage development
limb bud formation
embryonic skeletal joint morphogenesis
otic vesicle development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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