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Proteintech
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Immunogen sequence: LNINGSPMA PASVGNCSVG NCSPEAVWPK TEPLEMEVPQ APIQPFYSSP ELWISSLPMT DLDIKFQYRG KEYGQTMTVS NPQGCRLFYG DLGPMPDQEE LFGPVSLEQV KFPGPEHITN EKQKLFTSKL LDVMDRGLIL EVSGHAIYAI RLCQCKVYWS GPCAPSLVAP NLIERQKKVK LFCLETFLSD LIAHQKGQIE KQPPFEIYLC FGEEWPDGKP LERKLILVQV IPVVARMIYE MFSGDFTRSF DSGSVRLQIS TPDIKDNIVA QLKQLYRILQ TQESWQPMQP TPSMQLPPAL PPQ (166-467 aa encoded by BC014852)
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
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