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Proteintech
HSD17B3 Polyclonal Antibody
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Product Details
13415-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HSD17B3 Fusion Protein Ag4081 (25-177 aa encoded by BC034281)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VRFSRCVLL NYWKVLPKSF LRSMGQWAVI TGAGDGIGKA YSFELAKRGL NVVLISRTLE KLEAIATEIE RTTGRSVKII QADFTKDDIY EHIKEKLAGL EIGILVNNVG MLPNLLPSHF LNAPDEIQSL IHCNITSVVK MTQLILKHME SRQK (25-177 aa encoded by BC034281)
Target Information
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 17(beta)HSD type 3; 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; 17beta-HSD; estradiol 17 beta-dehydrogenase 3; Estradiol 17-beta-dehydrogenase 2; HSD17B3; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_1; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_2; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_3; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_4; hydroxysteroid (17-beta) dehydrogenase 3 isoform HSD17B3_5; hydroxysteroid dehydrogenase 3; Short chain dehydrogenase/reductase family 12C member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
Gene Aliases: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058, (Mouse) P70385, (Rat) O54939
Entrez Gene ID: (Human) 3293, (Mouse) 15487, (Rat) 117182
lipid metabolic process
steroid biosynthetic process
metabolic process
oxidation-reduction process
androgen biosynthetic process
male genitalia development
testosterone biosynthetic process
organic acid metabolic process
response to herbicide
response to metal ion
response to lead ion
response to organic cyclic compound
response to activity
response to insecticide
insecticide metabolic process
biphenyl metabolic process
phenol-containing compound metabolic process
hippocampus development
response to nutrient levels
cellular response to hormone stimulus
response to vitamin E
Leydig cell differentiation
response to L-ascorbic acid
response to estrogen
response to ethanol
response to arsenic-containing substance
response to cadmium ion
response to steroid hormone
response to corticosterone
response to fungicide
response to fatty acid
cellular response to antibiotic
cellular response to gonadotropin stimulus
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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