Uracil DNA Glycosylase - FAQs

What is UDG?

UDG (uracil-DNA-glycosylase) refers to a superfamily of enzymes comprising six sub-families. Family I UDG enzymes are called UNG, after the uracil-N-glycosylase gene. The terms UDG and UNG are commonly used interchangeably because they perform the same function in qPCR, namely, to remove Uracil from dU-containing DNA to prevent carryover contamination from previous PCRs. See the following link: https://www.thermofisher.com/uk/en/home/life-science/pcr/real-time-pcr/real-time-pcr-learning-center/real-time-pcr-basics/what-is-ung-udg.html