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NeoBiotechnologies
Glutamine Synthetase/GLUL Recombinant Rabbit Monoclonal Antibody (GLUL/8996R)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
2752-RBM25-P0
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
GLUL/8996R
Immunogen
Recombinant fragment (around aa 200-373) of human GLUL protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Protein A/G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: Human brain stomach or thyroid.
Cellular Location: Cytoplasm. Mitochondrion.
Target Information
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell proliferation-inducing protein 59; GLNA; Glutamate ammonia ligase; glutamate decarboxylase; glutamine synthase; glutamine synthetase I; palmitoyltransferase GLUL; Proliferation inducing protein 43; proliferation-inducing protein 43; unnamed protein product
Gene Aliases: DEE116; GLNS; GS; PIG43; PIG59
UniProt ID: (Human) P15104
Entrez Gene ID: (Human) 2752
glutamate catabolic process
cell proliferation
regulation of endothelial cell migration
protein palmitoylation
ribosome biogenesis
positive regulation of erythrocyte differentiation
cellular ammonia homeostasis
L-glutamine biosynthetic process
regulation of sprouting angiogenesis
regulation of protein localization to nucleolus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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