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Invitrogen
Calmyrin Monoclonal Antibody (1G8C8)
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FIGURE: 1 / 1
Calmyrin Antibody (35-4500) in WB
Western blot analysis was performed on tissue extract (30 µg lysate) of Mouse Brain (Lane 1). The blots were probed with Anti-Calmyrin Mouse Monoclonal Antibody (Product # 35-4500, 1-3 µg/mL) and detected by chemiluminescence using Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A28177, 0.4 µg/mL, 1:2500 dilution). A 21 kDa band corresponding to Calmyrin was observed in the tissue tested. Known quantity of protein samples were electrophoresed using Novex® NuPAGE® 12 % Bis-Tris gel (Product # NP0342BOX), ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
35-4500
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Hamster,
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1G8C8
Immunogen
Recombinant Calmyrin protein (full length)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alphabeta, which may implicate this protein as a regulatory molecule for alphabeta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcium and integrin binding 1 (calmyrin); calcium and integrin binding, protein kinase interacting protein; calcium-binding protein family member; CIB1; calmyrin; CIB; CIB1; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; EF-hand motif; kinase-interacting protein; protein kinase, DNA activated, catalytic polypeptide interacting protein; Sip2-28; SNK-interacting protein 2-28; testicular secretory protein Li 9; unnamed protein product
Gene Aliases: CIB; Cibkip; CIBP; EV3; Kip; KIP1; PRKDCIP; SIP2-28
UniProt ID: (Human) Q99828, (Mouse) Q9Z0F4
Entrez Gene ID: (Human) 10519, (Mouse) 23991
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
positive regulation of cell-matrix adhesion
response to ischemia
double-strand break repair
apoptotic process
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
endomitotic cell cycle
cell adhesion
spermatid development
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of neuron projection development
platelet formation
positive regulation of cell growth
positive regulation of cell migration
cytoplasmic microtubule organization
positive regulation of cell adhesion mediated by integrin
thrombopoietin-mediated signaling pathway
regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of catalytic activity
negative regulation of megakaryocyte differentiation
regulation of cell division
negative regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
positive regulation of calcineurin-NFAT signaling cascade
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of protein serine/threonine kinase activity
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of protein targeting to membrane
extrinsic apoptotic signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of protein localization to plasma membrane
cellular response to nerve growth factor stimulus
positive regulation of male germ cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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