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Invitrogen
Tyrosinase Monoclonal Antibody (T311)
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FIGURE: 1 / 9
Tyrosinase Antibody (35-6000) in WB
Western blot was performed using Anti-Tyrosinase Monoclonal Antibody (T311) (Product # 35-6000) and an 80 kDa band corresponding to Tyrosinase was observed across all the cell lines and tissues tested. Whole cell extracts (30 µg lysate) of A-375 (Lane 1), A-431 (Lane 2), SK-MEL-31 (Lane 3), SK-MEL-5 (Lane 4), B16-F10 (Lane 5), HaCaT (Lane 6), Mouse Retina (Lane 7), Mouse Lung (Lane 8) or Mouse Spleen (Lane 9) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0301BOX). Resolved proteins were then transferred onto a Ni... View More
Product Details
35-6000
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
T311
Immunogen
Recombinant tyrosinase protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Albino locus protein; LB24-AB; Monophenol monooxygenase; oculocutaneous albinism IA; SK29-AB; Tumor rejection antigen AB; Tyrosinase; tyrosinase precursor (EC 1.14.18.1)
Gene Aliases: albino; ATN; c; CMM8; OCA1; OCA1A; OCAIA; SHEP3; skc35; TYR
UniProt ID: (Human) P14679, (Mouse) P11344
Entrez Gene ID: (Human) 7299, (Mouse) 22173
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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