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Invitrogen
Claudin 7 Monoclonal Antibody (5D10F3)
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FIGURE: 1 / 14
Claudin 7 Antibody (37-4800) in ICC/IF
Immunofluorescence analysis of Claudin-7 was done on 90% confluent log phase SH-SY5Y cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Claudin-7 (5D10F3) Mouse Monoclonal Antibody (Product # 37-4800) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at r... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
37-4800
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5D10F3
Immunogen
Synthetic peptide derived from the C-terminal region of the human claudin-7 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: clostridium perfringens enterotoxin receptor-like 2; epididymis secretory sperm binding protein; unnamed protein product
Gene Aliases: CEPTRL2; claudin-1; CLDN-7; CPETRL2; Hs.84359
UniProt ID: (Human) O95471, (Mouse) Q9Z261
Entrez Gene ID: (Human) 1366, (Mouse) 53624
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
cell-cell junction organization
negative regulation of cell adhesion
positive regulation of cell proliferation
negative regulation of protein complex assembly
negative regulation of apoptotic process
positive regulation of cell motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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