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Invitrogen
HSP90 beta Monoclonal Antibody (H9010)
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FIGURE: 1 / 30
HSP90 beta Antibody (37-9400) in ICC/IF
Immunofluorescence analysis of Hsp90 beta was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Hsp90 beta (H9010) Mouse Monoclonal Antibody (Product # 37-9400) at 1:250 dilution in 0.1% BSA and incubated for 3 hours... View More
Product Details
37-9400
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rabbit
Published species
Human,
Mouse,
Rat,
Xenopus
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
H9010
Immunogen
Recombinant human HSP90-beta
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and some kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 90kDa heat shock protein; Heat shock 84 kDa; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein family C member 3; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; hsp90 beta; HSP90-beta; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; unnamed protein product
Gene Aliases: 90kDa; AL022974; C81438; D6S182; HSP84; Hsp84-1; Hsp90; HSP90AB1; HSP90B; HSPC2; HSPC3; HSPCB
UniProt ID: (Human) P08238, (Rabbit) P30947, (Mouse) P11499
Entrez Gene ID: (Chicken) 396188, (Human) 3326, (Rabbit) 100358690, (Mouse) 15516
ATP binding
protein dimerization activity
unfolded protein binding
nucleotide binding
RNA binding
double-stranded RNA binding
protein binding
ATPase activity
protein kinase regulator activity
kinase binding
protein kinase binding
MHC class II protein complex binding
nitric-oxide synthase regulator activity
TPR domain binding
heat shock protein binding
ubiquitin protein ligase binding
peptide binding
identical protein binding
protein homodimerization activity
histone deacetylase binding
ATP-dependent protein binding
protein binding involved in protein folding
cadherin binding
tau protein binding
DNA polymerase binding
protein phosphatase activator activity
disordered domain specific binding
ATP-dependent protein folding chaperone
receptor ligand inhibitor activity
histone methyltransferase binding
UTP binding
CTP binding
GTP binding
sulfonylurea receptor binding
dATP binding
ion channel binding
poly(A) RNA binding
Hsp90 family chaperone
protein folding
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of cell cycle arrest
negative regulation of transforming growth factor beta activation
placenta development
response to unfolded protein
telomere maintenance via telomerase
virion attachment to host cell
regulation of protein ubiquitination
regulation of protein localization
cellular response to heat
negative regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
protein stabilization
chaperone-mediated protein complex assembly
regulation of cell cycle
cellular response to interleukin-4
fibril organization
negative regulation of proteasomal protein catabolic process
telomerase holoenzyme complex assembly
positive regulation of protein localization to cell surface
response to stress
positive regulation of protein binding
positive regulation of protein import into nucleus, translocation
negative regulation of neuron apoptotic process
positive regulation of cell size
positive regulation of protein serine/threonine kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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